Phenolic compounds and biopotential of grape pomace extracts from Prokupac red grape variety
Samo za registrovane korisnike
2021
Autori
Milincić, Danijel D.Stanisavljević, Nemanja
Kostić, Aleksandar Z.
Soković Bajić, Svetlana
Kojić, Milan
Gašić, Uroš
Barac, Miroljub B.
Stanojević, Sladjana P.
Tesić, Zivoslav Lj.
Pesić, Mirjana B.
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Phenolic compounds and biopotential (antioxidant, cellular antioxidant and cytotoxic activity) of grape pomace (GP) skin, seed, stem and whole GP originating from indigenous red grape variety Prokupac were evaluated. The UHPLC-Orbitrap MS4 analysis showed the presence of 75 phenolic compounds (57 non-anthocyanins and 18 anthocyanins), among which considerable content of ethyl gallate was observed and malvidin-3-O-hexoside-(8,8)-methylmethyne-(epi)catechin was identified. The stem had significant content of stilbenoids. The GP seed and the whole GP showed the highest antioxidant activity estimated by ABTS(center dot)+ DPPH center dot and H2O2 scavenging assays that were strongly correlated with the presence of flavan-3-ols, phenolic acids and ethyl gallate. The GP skin exerted cellular antioxidant activity on adenocarcinoma cells (EC50 = 56.4 mg TPCs/mL) which was strongly correlated with the presence of flavonols and anthocyanins. These by-products of Prokupac red grape variety are a n...otable source of phenolic compounds with good antioxidant activity that can be extensively used in food and pharmaceutical industry.
Ključne reči:
Wine by-products / Phenolic compounds / Cytotoxic activity / Cellular antioxidant activity / Antioxidant activityIzvor:
Lwt-Food Science and Technology, 2021, 138Izdavač:
- Elsevier, Amsterdam
Finansiranje / projekti:
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200116 (Univerzitet u Beogradu, Poljoprivredni fakultet) (RS-MESTD-inst-2020-200116)
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200007 (Univerzitet u Beogradu, Institut za biološka istraživanja 'Siniša Stanković') (RS-MESTD-inst-2020-200007)
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200042 (Univerzitet u Beogradu, Institut za molekularnu genetiku i genetičko inženjerstvo) (RS-MESTD-inst-2020-200042)
DOI: 10.1016/j.lwt.2020.110739
ISSN: 0023-6438
WoS: 000608242300085
Scopus: 2-s2.0-85098179864
Institucija/grupa
Institut za molekularnu genetiku i genetičko inženjerstvoTY - JOUR AU - Milincić, Danijel D. AU - Stanisavljević, Nemanja AU - Kostić, Aleksandar Z. AU - Soković Bajić, Svetlana AU - Kojić, Milan AU - Gašić, Uroš AU - Barac, Miroljub B. AU - Stanojević, Sladjana P. AU - Tesić, Zivoslav Lj. AU - Pesić, Mirjana B. PY - 2021 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/1482 AB - Phenolic compounds and biopotential (antioxidant, cellular antioxidant and cytotoxic activity) of grape pomace (GP) skin, seed, stem and whole GP originating from indigenous red grape variety Prokupac were evaluated. The UHPLC-Orbitrap MS4 analysis showed the presence of 75 phenolic compounds (57 non-anthocyanins and 18 anthocyanins), among which considerable content of ethyl gallate was observed and malvidin-3-O-hexoside-(8,8)-methylmethyne-(epi)catechin was identified. The stem had significant content of stilbenoids. The GP seed and the whole GP showed the highest antioxidant activity estimated by ABTS(center dot)+ DPPH center dot and H2O2 scavenging assays that were strongly correlated with the presence of flavan-3-ols, phenolic acids and ethyl gallate. The GP skin exerted cellular antioxidant activity on adenocarcinoma cells (EC50 = 56.4 mg TPCs/mL) which was strongly correlated with the presence of flavonols and anthocyanins. These by-products of Prokupac red grape variety are a notable source of phenolic compounds with good antioxidant activity that can be extensively used in food and pharmaceutical industry. PB - Elsevier, Amsterdam T2 - Lwt-Food Science and Technology T1 - Phenolic compounds and biopotential of grape pomace extracts from Prokupac red grape variety VL - 138 DO - 10.1016/j.lwt.2020.110739 ER -
@article{ author = "Milincić, Danijel D. and Stanisavljević, Nemanja and Kostić, Aleksandar Z. and Soković Bajić, Svetlana and Kojić, Milan and Gašić, Uroš and Barac, Miroljub B. and Stanojević, Sladjana P. and Tesić, Zivoslav Lj. and Pesić, Mirjana B.", year = "2021", abstract = "Phenolic compounds and biopotential (antioxidant, cellular antioxidant and cytotoxic activity) of grape pomace (GP) skin, seed, stem and whole GP originating from indigenous red grape variety Prokupac were evaluated. The UHPLC-Orbitrap MS4 analysis showed the presence of 75 phenolic compounds (57 non-anthocyanins and 18 anthocyanins), among which considerable content of ethyl gallate was observed and malvidin-3-O-hexoside-(8,8)-methylmethyne-(epi)catechin was identified. The stem had significant content of stilbenoids. The GP seed and the whole GP showed the highest antioxidant activity estimated by ABTS(center dot)+ DPPH center dot and H2O2 scavenging assays that were strongly correlated with the presence of flavan-3-ols, phenolic acids and ethyl gallate. The GP skin exerted cellular antioxidant activity on adenocarcinoma cells (EC50 = 56.4 mg TPCs/mL) which was strongly correlated with the presence of flavonols and anthocyanins. These by-products of Prokupac red grape variety are a notable source of phenolic compounds with good antioxidant activity that can be extensively used in food and pharmaceutical industry.", publisher = "Elsevier, Amsterdam", journal = "Lwt-Food Science and Technology", title = "Phenolic compounds and biopotential of grape pomace extracts from Prokupac red grape variety", volume = "138", doi = "10.1016/j.lwt.2020.110739" }
Milincić, D. D., Stanisavljević, N., Kostić, A. Z., Soković Bajić, S., Kojić, M., Gašić, U., Barac, M. B., Stanojević, S. P., Tesić, Z. Lj.,& Pesić, M. B.. (2021). Phenolic compounds and biopotential of grape pomace extracts from Prokupac red grape variety. in Lwt-Food Science and Technology Elsevier, Amsterdam., 138. https://doi.org/10.1016/j.lwt.2020.110739
Milincić DD, Stanisavljević N, Kostić AZ, Soković Bajić S, Kojić M, Gašić U, Barac MB, Stanojević SP, Tesić ZL, Pesić MB. Phenolic compounds and biopotential of grape pomace extracts from Prokupac red grape variety. in Lwt-Food Science and Technology. 2021;138. doi:10.1016/j.lwt.2020.110739 .
Milincić, Danijel D., Stanisavljević, Nemanja, Kostić, Aleksandar Z., Soković Bajić, Svetlana, Kojić, Milan, Gašić, Uroš, Barac, Miroljub B., Stanojević, Sladjana P., Tesić, Zivoslav Lj., Pesić, Mirjana B., "Phenolic compounds and biopotential of grape pomace extracts from Prokupac red grape variety" in Lwt-Food Science and Technology, 138 (2021), https://doi.org/10.1016/j.lwt.2020.110739 . .