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Приказ резултата 1-10 од 2234
Mitochondrial DNA Perspective of Serbian Genetic Diversity
(Wiley, Hoboken, 2015)
Although south-Slavic populations have been studied to date from various aspects, the population of Serbia, occupying the central part of the Balkan Peninsula, is still genetically understudied at least at the level of ...
Molekularni markeri u sistemskoj sklerozi: geni kandidati i terapijski modaliteti / Molecular markers in systemic sclerosis: candidate genes and therapeutic modalities
(Beograd : Institut za molekularnu genetiku i genetičko inženjerstvo, 2021)
Sistemska skleroza je izuzetno složeno i heterogeno oboljenje u pogledu kliničke prezentacije, progresije
bolesti, zahvaćenosti organa i ishodu. Na individualnom nivou, ova složenost predstavlja izazov u predviđanju
progresije ...
Saquinavir-NO inhibits S6 kinase activity, impairs secretion of the encephalytogenic cytokines interleukin-17 and interferon-gamma and ameliorates experimental autoimmune encephalomyelitis
(Elsevier Science Bv, Amsterdam, 2013)
NO-hybridization of the HIV protease inhibitor Saquinavir generates a new chemical entity named Saq-NO, that retains the anti-viral activity and exerts lower toxicity. We show that Saq-NO inhibited the generation of various ...
Molecular characterization of Pseudomonas syringae isolates from fruit trees and raspberry in Serbia
(Springer, Dordrecht, 2012)
Infection of fruit trees by Pseudomonas syringae is a potentially serious problem that may limit the establishment and sustained productivity of pome and stone fruit orchards in Serbia. To estimate possible diversity of ...
Early growth response protein 1 acts as an activator of SOX18 promoter
(Nature Publishing Group, New York, 2010)
Sex-determining region Y box 18 (Sox18/SOX18) gene is an important regulator of vascular development playing a role in endothelial cell specification or differentiation, angiogenesis and atherogenesis. The aim of this study ...
ZBP-89 and Sp3 down-regulate while NF-Y up-regulates SOX18 promoter activity in HeLa cells
(Springer, Dordrecht, 2009)
The aim of this study has been to identify transcription factors involved in transcriptional regulation of the human SOX18 gene expression. Structural analysis revealed that the SOX18 promoter lacks a TATA box, but is ...
Učestalost S i Z mutacija u genu za alfa 1-antitripsin kod pacijenata sa bolestima pankreasa / Prevalence of S and Z alpha 1-antitrypsin mutations in patients with pancreatic diseases in Serbian population
(Društvo genetičara Srbije, Beograd, 2010)
Jedan od osnovnih izazova u proučavanju patologije bolesti pankreasa predstavlja dalje razjašnjavanje uloge proteaza i antiproteaza, zbog toga što poremećena ravnoteža između njih može dovesti do oštećenja pankreasa. Alfa ...
Extreme sensitivity to acenocoumarol therapy in patient with both VKORC.-1639 A/A and CYP2C9*1/*3 genotypes
(Springer, Dordrecht, 2011)
The initiation phase of vitamin K antagonist (VKA) is a challenging and demanding process that can result in adverse event such as bleeding. Dosing is influenced by a variety of acquired factors, while another factor that ...
In silico structural survey of newly identified late embryogenesis abundant proteins (LEAPs) from Ramonda serbica and their structure - function relationship
(Virtual symposium celebrating the 50th anniversary of the Protein Data Bank, May 4–5, 2021)
Desiccation or extreme water loss leads to protein denaturation, aggregation, and degradation and impairs membrane lipid fluidity, resulting in loss of membrane integrity at the cellular level. The induction of late ...
Cordyceps sinensis: Genotoxic Potential in Human Peripheral Blood Cells and Antigenotoxic Properties Against Hydrogen Peroxide by Comet Assay
(InnoVision Communications, 2016)
Context Cordyceps sinensis (C sinensis) is a well-known, traditional, Chinese medicinal mushroom, valued for its beneficial properties for human health. C sinensis has been reported to have immunomodulatory, anticancer, ...