Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites
Autori
Malagurski, IvanaLević, Steva
Pantić, Milena
Matijašević, Danka
Mitrić, Miodrag
Pavlović, Vladimir
Dimitrijević-Branković, Suzana
Članak u časopisu (Recenzirana verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
New bioactive and antimicrobial biomaterials were produced by alginate-mediated biomineralization with Zn-mineral phase. The synthesis procedure is simple, cost-effective and resulted in. two different Zn-mineralized alginate nanocomposites, Zn-carbonate/Zn-alginate and Zn-phosphate/Zn-alginate. The presence of Zn-mineral phase and its type, have significantly affected nanocomposite morphology, stability, total metallic loading and potential to release Zn(II) in physiological environment. Antimicrobial experiments showed that both types of Zn-mineralized nanocomposites exhibit strong antimicrobial effect against Escherichia coli, Staphylococcus aureus and Candida albicans. These results suggest that alginate biomineralization, where minerals are salts of essential metallic ions like Zn(II), represents a'good strategy for designing multifunctional biomaterials for potential biomedical applications.
Ključne reči:
Zinc / Nanocomposite / Biomineralization / Antimicrobial activity / AlginateIzvor:
Carbohydrate Polymers, 2017, 165, 313-321Izdavač:
- Elsevier Sci Ltd, Oxford
Finansiranje / projekti:
- Sinteza, razvoj tehnologija dobijanja i primena nanostrukturnih multifunkcionalnih materijala definisanih svojstava (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45019)
- Usmerena sinteza, struktura i svojstva multifunkcionalnih materijala (RS-MESTD-Basic Research (BR or ON)-172057)
Napomena:
- This is the peer reviewed version of the paper: Malagurski, I., Levic, S., Pantic, M., Matijasevic, D., Mitric, M., Pavlovic, V., & Dimitrijevic-Brankovic, S. (2017). Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites. Carbohydrate Polymers, 165, 313–321. https://doi.org/10.1016/j.carbpol.2017.02.064
Povezane informacije:
- Druga verzija
https://doi.org/10.1016/j.carbpol.2017.02.064
DOI: 10.1016/j.carbpol.2017.02.064
ISSN: 0144-8617
PubMed: 28363555
WoS: 000399261900035
Scopus: 2-s2.0-85013763459
Institucija/grupa
Institut za molekularnu genetiku i genetičko inženjerstvoTY - JOUR AU - Malagurski, Ivana AU - Lević, Steva AU - Pantić, Milena AU - Matijašević, Danka AU - Mitrić, Miodrag AU - Pavlović, Vladimir AU - Dimitrijević-Branković, Suzana PY - 2017 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/1054 AB - New bioactive and antimicrobial biomaterials were produced by alginate-mediated biomineralization with Zn-mineral phase. The synthesis procedure is simple, cost-effective and resulted in. two different Zn-mineralized alginate nanocomposites, Zn-carbonate/Zn-alginate and Zn-phosphate/Zn-alginate. The presence of Zn-mineral phase and its type, have significantly affected nanocomposite morphology, stability, total metallic loading and potential to release Zn(II) in physiological environment. Antimicrobial experiments showed that both types of Zn-mineralized nanocomposites exhibit strong antimicrobial effect against Escherichia coli, Staphylococcus aureus and Candida albicans. These results suggest that alginate biomineralization, where minerals are salts of essential metallic ions like Zn(II), represents a'good strategy for designing multifunctional biomaterials for potential biomedical applications. PB - Elsevier Sci Ltd, Oxford T2 - Carbohydrate Polymers T1 - Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites EP - 321 SP - 313 VL - 165 DO - 10.1016/j.carbpol.2017.02.064 ER -
@article{ author = "Malagurski, Ivana and Lević, Steva and Pantić, Milena and Matijašević, Danka and Mitrić, Miodrag and Pavlović, Vladimir and Dimitrijević-Branković, Suzana", year = "2017", abstract = "New bioactive and antimicrobial biomaterials were produced by alginate-mediated biomineralization with Zn-mineral phase. The synthesis procedure is simple, cost-effective and resulted in. two different Zn-mineralized alginate nanocomposites, Zn-carbonate/Zn-alginate and Zn-phosphate/Zn-alginate. The presence of Zn-mineral phase and its type, have significantly affected nanocomposite morphology, stability, total metallic loading and potential to release Zn(II) in physiological environment. Antimicrobial experiments showed that both types of Zn-mineralized nanocomposites exhibit strong antimicrobial effect against Escherichia coli, Staphylococcus aureus and Candida albicans. These results suggest that alginate biomineralization, where minerals are salts of essential metallic ions like Zn(II), represents a'good strategy for designing multifunctional biomaterials for potential biomedical applications.", publisher = "Elsevier Sci Ltd, Oxford", journal = "Carbohydrate Polymers", title = "Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites", pages = "321-313", volume = "165", doi = "10.1016/j.carbpol.2017.02.064" }
Malagurski, I., Lević, S., Pantić, M., Matijašević, D., Mitrić, M., Pavlović, V.,& Dimitrijević-Branković, S.. (2017). Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites. in Carbohydrate Polymers Elsevier Sci Ltd, Oxford., 165, 313-321. https://doi.org/10.1016/j.carbpol.2017.02.064
Malagurski I, Lević S, Pantić M, Matijašević D, Mitrić M, Pavlović V, Dimitrijević-Branković S. Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites. in Carbohydrate Polymers. 2017;165:313-321. doi:10.1016/j.carbpol.2017.02.064 .
Malagurski, Ivana, Lević, Steva, Pantić, Milena, Matijašević, Danka, Mitrić, Miodrag, Pavlović, Vladimir, Dimitrijević-Branković, Suzana, "Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites" in Carbohydrate Polymers, 165 (2017):313-321, https://doi.org/10.1016/j.carbpol.2017.02.064 . .