Antioxidant and cytotoxic activity of red wine after in vitro simulated digestion in the presence of complex food matrix
Nema prikaza
Autori
Đorđević, Neda O.Stanisavljević, Nemanja
Todorovic Vukotić, Nevena
Novović, Katarina
Zakula, Jelena J.
Stanković, Dalibor
Pajović, Snežana B.
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The beneficial effect of moderate wine consumption is attributed to its micronutrients, especially polyphenols and largely depends on the digestion process. This work aimed to examine the influence of in vitro simulated digestion in the presence of complex food matrix on antioxidant and cytotoxic activity of red wine. The obtained results showed that total phenolic content of wine sample after in vitro digestion was higher compared to undigested wine, while the antioxidant activity of these samples was similar before and after digestion. Furthermore, it has been noticed that digested wine showed cytotoxic activity on SKBR3 breast adenocarcinoma cells near 20% after 72 h of treatment. This pioneering study that examined biological potential of in vitro digested wine in the presence of complex food matrix indicate that antioxidant and cytotoxic activity of red wine is preserved after digestion.
Ključne reči:
Red wine / in vitro digestion / cytotoxic activity / cyclic voltammetry / antioxidant activityIzvor:
Natural Product Research, 2022Izdavač:
- Taylor & Francis Ltd, Abingdon
Finansiranje / projekti:
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200017 (Univerzitet u Beogradu, Institut za nuklearne nauke Vinča, Beograd-Vinča) (RS-MESTD-inst-2020-200017)
DOI: 10.1080/14786419.2022.2095380
ISSN: 1478-6419
WoS: 000825251200001
Scopus: 2-s2.0-85133519942
Institucija/grupa
Institut za molekularnu genetiku i genetičko inženjerstvoTY - JOUR AU - Đorđević, Neda O. AU - Stanisavljević, Nemanja AU - Todorovic Vukotić, Nevena AU - Novović, Katarina AU - Zakula, Jelena J. AU - Stanković, Dalibor AU - Pajović, Snežana B. PY - 2022 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/1584 AB - The beneficial effect of moderate wine consumption is attributed to its micronutrients, especially polyphenols and largely depends on the digestion process. This work aimed to examine the influence of in vitro simulated digestion in the presence of complex food matrix on antioxidant and cytotoxic activity of red wine. The obtained results showed that total phenolic content of wine sample after in vitro digestion was higher compared to undigested wine, while the antioxidant activity of these samples was similar before and after digestion. Furthermore, it has been noticed that digested wine showed cytotoxic activity on SKBR3 breast adenocarcinoma cells near 20% after 72 h of treatment. This pioneering study that examined biological potential of in vitro digested wine in the presence of complex food matrix indicate that antioxidant and cytotoxic activity of red wine is preserved after digestion. PB - Taylor & Francis Ltd, Abingdon T2 - Natural Product Research T1 - Antioxidant and cytotoxic activity of red wine after in vitro simulated digestion in the presence of complex food matrix DO - 10.1080/14786419.2022.2095380 ER -
@article{ author = "Đorđević, Neda O. and Stanisavljević, Nemanja and Todorovic Vukotić, Nevena and Novović, Katarina and Zakula, Jelena J. and Stanković, Dalibor and Pajović, Snežana B.", year = "2022", abstract = "The beneficial effect of moderate wine consumption is attributed to its micronutrients, especially polyphenols and largely depends on the digestion process. This work aimed to examine the influence of in vitro simulated digestion in the presence of complex food matrix on antioxidant and cytotoxic activity of red wine. The obtained results showed that total phenolic content of wine sample after in vitro digestion was higher compared to undigested wine, while the antioxidant activity of these samples was similar before and after digestion. Furthermore, it has been noticed that digested wine showed cytotoxic activity on SKBR3 breast adenocarcinoma cells near 20% after 72 h of treatment. This pioneering study that examined biological potential of in vitro digested wine in the presence of complex food matrix indicate that antioxidant and cytotoxic activity of red wine is preserved after digestion.", publisher = "Taylor & Francis Ltd, Abingdon", journal = "Natural Product Research", title = "Antioxidant and cytotoxic activity of red wine after in vitro simulated digestion in the presence of complex food matrix", doi = "10.1080/14786419.2022.2095380" }
Đorđević, N. O., Stanisavljević, N., Todorovic Vukotić, N., Novović, K., Zakula, J. J., Stanković, D.,& Pajović, S. B.. (2022). Antioxidant and cytotoxic activity of red wine after in vitro simulated digestion in the presence of complex food matrix. in Natural Product Research Taylor & Francis Ltd, Abingdon.. https://doi.org/10.1080/14786419.2022.2095380
Đorđević NO, Stanisavljević N, Todorovic Vukotić N, Novović K, Zakula JJ, Stanković D, Pajović SB. Antioxidant and cytotoxic activity of red wine after in vitro simulated digestion in the presence of complex food matrix. in Natural Product Research. 2022;. doi:10.1080/14786419.2022.2095380 .
Đorđević, Neda O., Stanisavljević, Nemanja, Todorovic Vukotić, Nevena, Novović, Katarina, Zakula, Jelena J., Stanković, Dalibor, Pajović, Snežana B., "Antioxidant and cytotoxic activity of red wine after in vitro simulated digestion in the presence of complex food matrix" in Natural Product Research (2022), https://doi.org/10.1080/14786419.2022.2095380 . .