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A 3D in vitro cell culture model based on perfused bone-like scaffolds for healthy and pathological bone research
dc.creator | Banićević, Ivana | |
dc.creator | Milošević, Mia | |
dc.creator | Petrović, Jelena | |
dc.creator | Menshikh, Ksenia | |
dc.creator | Milivojević, Milena | |
dc.creator | Stevanović, Milena | |
dc.creator | Janković, Radmila | |
dc.creator | Cochis, Andrea | |
dc.creator | Bella, Elena Della | |
dc.creator | Stoddart, Martin | |
dc.creator | Rimondini, Lia | |
dc.creator | Stojkovska, Jasmina | |
dc.creator | Obradović, Bojana | |
dc.date.accessioned | 2024-04-30T19:47:58Z | |
dc.date.available | 2024-04-30T19:47:58Z | |
dc.date.issued | 2024 | |
dc.identifier.issn | 2217-7426 | |
dc.identifier.uri | https://www.ache-pub.org.rs/index.php/HemInd/article/view/1261 | |
dc.identifier.uri | https://imagine.imgge.bg.ac.rs/handle/123456789/2363 | |
dc.description.abstract | Comprehensive research, particularly in evaluating drug efficacy, still heavily relies on the results obtained by the utilization of cell monolayers and animals. However, the inherent limitations of these models such as their physiological disparities from humans pose significant obstacles to acquiring reliable results thus impeding further scientific progression. To address this challenge, 3D in vitro cell culture models emerged as physiologically relevant models having the potential to enhance research and drug discovery. Our study aimed to develop a 3D in vitro cell culture model based on bone-like scaffolds in conjunction with a perfusion bioreactor (“3D Perfuse”, Innovation Center FTM, Belgrade, Serbia) for studying both physiological and pathological (i.e. tumors) bone conditions. | |
dc.language | en | |
dc.relation | info:eu-repo/grantAgreement/EC/H2020/860462/EU// | |
dc.relation | European Union’s Horizon 2020 Research and Innovation programme (GA Nos 952033) | |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.source | Hemijska industrija (Chemical Industry) | |
dc.subject | Alginate composite scaffolds | |
dc.subject | perfusion bioreactor | |
dc.subject | osteosarcoma | |
dc.subject | tumor engineering | |
dc.subject | mesenchymal stem cells | |
dc.title | A 3D in vitro cell culture model based on perfused bone-like scaffolds for healthy and pathological bone research | |
dc.type | conferenceObject | |
dc.rights.license | BY-NC-ND | |
dc.citation.epage | 19 | |
dc.citation.issue | 1S | |
dc.citation.spage | 19 | |
dc.citation.volume | 78 | |
dc.identifier.fulltext | https://imagine.imgge.bg.ac.rs/bitstream/id/787481/bitstream_787481.pdf | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_imagine_2363 | |
dc.type.version | publishedVersion |