Novel formulation for maintaining the integrity of lipid vesicles (Peptosome)
Остало (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Modern skin care formulations contain liposomes – nano-spherical vesicles. Liposomes are the best
delivery system for the controlled release of active and sensitive ingredients (e.g. vitamin C) into the
deeper skin layers. Formulations with liposomes have been shown to release vitamin C ten times faster
into the deeper skin layers, while protecting the vitamin C from oxidation and degradation. However, as
soon as the packaging of such a formulation is opened, its contents are exposed to atmospheric oxygen
and the ingredients, including the liposomes, oxidise and dry out. Our solution: PEPTOSOME extends the
shelf-life of expensive liposome-based skin formulations by stabilising both, the liposomes and their
contents.
The inspiration for PEPTOSOME lies in the ancient and remarkable phenomenon of resurrection plants.
Part of this dehydration survival strategy based on specific, flexible proteins has been implemented in
PEPTOSOME. As our invention PEPTOSOME is a formulation based... on a flexible peptide structure, it
circumvents the lack of selectivity of small molecules and provides better affinity and coverage. The safety
and skin-beneficial function of the extracts of these proteins/peptides is proven. PEPTOSOME is
completely innovative, cost-effective, easy to transport (at room temperature), eco-friendly, and contains
no toxic chemicals. Our invention is also suitable for stabilising liposomes loaded with other skin-beneficial
substances (anti-ageing agents, moisturisers, etc.), suitable for personalised care. Finally, LEAPOSOME can
also be used with liposomes in the food industry, pharmacy, medicine and organic farming.
Извор:
Science Fund of the Republic of Serbia, Program Proof of Concept, 2024Финансирање / пројекти:
- LEAPOSOME - Innovative Solution for Liposome Stabilisation (RS-ScienceFundRS-DokazKoncepta-11211)
Напомена:
- Principal Investigator: Dr Marija Vidović, IMGGE
- Duration period: 2024-2025
Колекције
Институција/група
Institut za molekularnu genetiku i genetičko inženjerstvoTY - GEN PY - 2024 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/2410 AB - Modern skin care formulations contain liposomes – nano-spherical vesicles. Liposomes are the best delivery system for the controlled release of active and sensitive ingredients (e.g. vitamin C) into the deeper skin layers. Formulations with liposomes have been shown to release vitamin C ten times faster into the deeper skin layers, while protecting the vitamin C from oxidation and degradation. However, as soon as the packaging of such a formulation is opened, its contents are exposed to atmospheric oxygen and the ingredients, including the liposomes, oxidise and dry out. Our solution: PEPTOSOME extends the shelf-life of expensive liposome-based skin formulations by stabilising both, the liposomes and their contents. The inspiration for PEPTOSOME lies in the ancient and remarkable phenomenon of resurrection plants. Part of this dehydration survival strategy based on specific, flexible proteins has been implemented in PEPTOSOME. As our invention PEPTOSOME is a formulation based on a flexible peptide structure, it circumvents the lack of selectivity of small molecules and provides better affinity and coverage. The safety and skin-beneficial function of the extracts of these proteins/peptides is proven. PEPTOSOME is completely innovative, cost-effective, easy to transport (at room temperature), eco-friendly, and contains no toxic chemicals. Our invention is also suitable for stabilising liposomes loaded with other skin-beneficial substances (anti-ageing agents, moisturisers, etc.), suitable for personalised care. Finally, LEAPOSOME can also be used with liposomes in the food industry, pharmacy, medicine and organic farming. T2 - Science Fund of the Republic of Serbia, Program Proof of Concept T1 - Novel formulation for maintaining the integrity of lipid vesicles (Peptosome) UR - https://hdl.handle.net/21.15107/rcub_imagine_2410 ER -
@misc{ year = "2024", abstract = "Modern skin care formulations contain liposomes – nano-spherical vesicles. Liposomes are the best delivery system for the controlled release of active and sensitive ingredients (e.g. vitamin C) into the deeper skin layers. Formulations with liposomes have been shown to release vitamin C ten times faster into the deeper skin layers, while protecting the vitamin C from oxidation and degradation. However, as soon as the packaging of such a formulation is opened, its contents are exposed to atmospheric oxygen and the ingredients, including the liposomes, oxidise and dry out. Our solution: PEPTOSOME extends the shelf-life of expensive liposome-based skin formulations by stabilising both, the liposomes and their contents. The inspiration for PEPTOSOME lies in the ancient and remarkable phenomenon of resurrection plants. Part of this dehydration survival strategy based on specific, flexible proteins has been implemented in PEPTOSOME. As our invention PEPTOSOME is a formulation based on a flexible peptide structure, it circumvents the lack of selectivity of small molecules and provides better affinity and coverage. The safety and skin-beneficial function of the extracts of these proteins/peptides is proven. PEPTOSOME is completely innovative, cost-effective, easy to transport (at room temperature), eco-friendly, and contains no toxic chemicals. Our invention is also suitable for stabilising liposomes loaded with other skin-beneficial substances (anti-ageing agents, moisturisers, etc.), suitable for personalised care. Finally, LEAPOSOME can also be used with liposomes in the food industry, pharmacy, medicine and organic farming.", journal = "Science Fund of the Republic of Serbia, Program Proof of Concept", title = "Novel formulation for maintaining the integrity of lipid vesicles (Peptosome)", url = "https://hdl.handle.net/21.15107/rcub_imagine_2410" }
(2024). Novel formulation for maintaining the integrity of lipid vesicles (Peptosome). in Science Fund of the Republic of Serbia, Program Proof of Concept. https://hdl.handle.net/21.15107/rcub_imagine_2410
Novel formulation for maintaining the integrity of lipid vesicles (Peptosome). in Science Fund of the Republic of Serbia, Program Proof of Concept. 2024;. https://hdl.handle.net/21.15107/rcub_imagine_2410 .
"Novel formulation for maintaining the integrity of lipid vesicles (Peptosome)" in Science Fund of the Republic of Serbia, Program Proof of Concept (2024), https://hdl.handle.net/21.15107/rcub_imagine_2410 .