TY  - JOUR
AU  - Troha, Kaja
AU  - Vozel, Domen
AU  - Arko, Matevž
AU  - Bedina Zavec, Apolonija
AU  - Dolinar, Drago
AU  - Hočevar, Matej
AU  - Jan, Zala
AU  - Kisovec, Matic
AU  - Kocjančič, Boštjan
AU  - Pađen, Ljubiša
AU  - Pajnič, Manca
AU  - Penič, Samo
AU  - Romolo, Anna
AU  - Repar, Neža
AU  - Spasovski, Vesna
AU  - Steiner, Nejc
AU  - Šuštar, Vid
AU  - Iglič, Aleš
AU  - Drobne, Damjana
AU  - Kogej, Ksenija
AU  - Battelino, Saba
AU  - Kralj-Iglič, Veronika
PY  - 2023
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/2087
AB  - The preparation of autologous platelet and extracellular vesicle-rich plasma (PVRP) has been explored in many medical fields with the aim to benefit from its healing potential. In parallel, efforts are being invested to understand the function and dynamics of PVRP that is complex in its composition and interactions. Some clinical evidence reveals beneficial effects of PVRP, while some report that there were no effects. To optimize the preparation methods, functions and mechanisms of PVRP, its constituents should be better understood. With the intention to promote further studies of autologous therapeutic PVRP, we performed a review on some topics regarding PVRP composition, harvesting, assessment and preservation, and also on clinical experience following PVRP application in humans and animals. Besides the acknowledged actions of platelets, leukocytes and different molecules, we focus on extracellular vesicles that were found abundant in PVRP.
PB  - MDPI
T2  - International Journal of Molecular Sciences
T1  - Autologous Platelet and Extracellular Vesicle-Rich Plasma as Therapeutic Fluid: A Review
IS  - 4
SP  - 3420
VL  - 24
DO  - 10.3390/ijms24043420
ER  - 

@article{
author = "Troha, Kaja and Vozel, Domen and Arko, Matevž and Bedina Zavec, Apolonija and Dolinar, Drago and Hočevar, Matej and Jan, Zala and Kisovec, Matic and Kocjančič, Boštjan and Pađen, Ljubiša and Pajnič, Manca and Penič, Samo and Romolo, Anna and Repar, Neža and Spasovski, Vesna and Steiner, Nejc and Šuštar, Vid and Iglič, Aleš and Drobne, Damjana and Kogej, Ksenija and Battelino, Saba and Kralj-Iglič, Veronika",
year = "2023",
abstract = "The preparation of autologous platelet and extracellular vesicle-rich plasma (PVRP) has been explored in many medical fields with the aim to benefit from its healing potential. In parallel, efforts are being invested to understand the function and dynamics of PVRP that is complex in its composition and interactions. Some clinical evidence reveals beneficial effects of PVRP, while some report that there were no effects. To optimize the preparation methods, functions and mechanisms of PVRP, its constituents should be better understood. With the intention to promote further studies of autologous therapeutic PVRP, we performed a review on some topics regarding PVRP composition, harvesting, assessment and preservation, and also on clinical experience following PVRP application in humans and animals. Besides the acknowledged actions of platelets, leukocytes and different molecules, we focus on extracellular vesicles that were found abundant in PVRP.",
publisher = "MDPI",
journal = "International Journal of Molecular Sciences",
title = "Autologous Platelet and Extracellular Vesicle-Rich Plasma as Therapeutic Fluid: A Review",
number = "4",
pages = "3420",
volume = "24",
doi = "10.3390/ijms24043420"
}

Troha, K., Vozel, D., Arko, M., Bedina Zavec, A., Dolinar, D., Hočevar, M., Jan, Z., Kisovec, M., Kocjančič, B., Pađen, L., Pajnič, M., Penič, S., Romolo, A., Repar, N., Spasovski, V., Steiner, N., Šuštar, V., Iglič, A., Drobne, D., Kogej, K., Battelino, S.,& Kralj-Iglič, V.. (2023). Autologous Platelet and Extracellular Vesicle-Rich Plasma as Therapeutic Fluid: A Review. in International Journal of Molecular Sciences
MDPI., 24(4), 3420.
https://doi.org/10.3390/ijms24043420

Troha K, Vozel D, Arko M, Bedina Zavec A, Dolinar D, Hočevar M, Jan Z, Kisovec M, Kocjančič B, Pađen L, Pajnič M, Penič S, Romolo A, Repar N, Spasovski V, Steiner N, Šuštar V, Iglič A, Drobne D, Kogej K, Battelino S, Kralj-Iglič V. Autologous Platelet and Extracellular Vesicle-Rich Plasma as Therapeutic Fluid: A Review. in International Journal of Molecular Sciences. 2023;24(4):3420.
doi:10.3390/ijms24043420 .

Troha, Kaja, Vozel, Domen, Arko, Matevž, Bedina Zavec, Apolonija, Dolinar, Drago, Hočevar, Matej, Jan, Zala, Kisovec, Matic, Kocjančič, Boštjan, Pađen, Ljubiša, Pajnič, Manca, Penič, Samo, Romolo, Anna, Repar, Neža, Spasovski, Vesna, Steiner, Nejc, Šuštar, Vid, Iglič, Aleš, Drobne, Damjana, Kogej, Ksenija, Battelino, Saba, Kralj-Iglič, Veronika, "Autologous Platelet and Extracellular Vesicle-Rich Plasma as Therapeutic Fluid: A Review" in International Journal of Molecular Sciences, 24, no. 4 (2023):3420,
https://doi.org/10.3390/ijms24043420 . .