TY  - CONF
AU  - Zavisić, G.
AU  - Ristić, S.
AU  - Petricević, S.
AU  - Jovanović, J. Novakovic
AU  - Radulović, Z.
AU  - Petković, B. Janac
AU  - Strahinić, Ivana
AU  - Piperski, V.
PY  - 2015
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/888
AB  - We investigated the potential probiotic properties of indigenous lactic acid bacteria (LAB) isolated from Serbian homemade cheese. Seventeen LAB strains were isolated and characterised using standard protocols. One of the strains showed several probiotic properties: survival at low pH and in bile salts solution, antimicrobial activity, susceptibility to antibiotics and adhesion to hexodecane. DNA analysis identified the isolate as Lactobacillus casei, hereafter named Lactobacillus casei 5s. The lipid lowering effect of Lactobacillus casei 5s was evaluated in vivo using a hyperlipidemic rat model. Orally administered Lactobacillus casei 5s significantly decreased the elevated total serum cholesterol and triglycerides, and attenuated macro vesicular steatosis in the liver. Moreover, Lactobacillus casei 5s improved the intestinal microbial balance in favour of lactobacilli, while decreasing the number of Escherichia coli cells. The bacteria were re-isolated and identified from the surface of the intestinal mucosa and from the faecal samples of treated animals, indicating adhesiveness and colonisation ability. The results of an acute oral toxicity study in mice and the absence of translocation to other organs demonstrated the safety of the strain. In conclusion, Lactobacillus casei 5s demonstrated promising probiotic potential and might be a good candidate for more detailed investigations.
PB  - Wageningen Academic Publishers, Wageningen
C3  - Beneficial Microbes
T1  - Characterisation and preliminary lipid-lowering evaluation of Lactobacillus isolated from a traditional Serbian dairy product
EP  - 128
IS  - 1
SP  - 119
VL  - 6
DO  - 10.3920/BM2014.0018
ER  - 

@conference{
author = "Zavisić, G. and Ristić, S. and Petricević, S. and Jovanović, J. Novakovic and Radulović, Z. and Petković, B. Janac and Strahinić, Ivana and Piperski, V.",
year = "2015",
abstract = "We investigated the potential probiotic properties of indigenous lactic acid bacteria (LAB) isolated from Serbian homemade cheese. Seventeen LAB strains were isolated and characterised using standard protocols. One of the strains showed several probiotic properties: survival at low pH and in bile salts solution, antimicrobial activity, susceptibility to antibiotics and adhesion to hexodecane. DNA analysis identified the isolate as Lactobacillus casei, hereafter named Lactobacillus casei 5s. The lipid lowering effect of Lactobacillus casei 5s was evaluated in vivo using a hyperlipidemic rat model. Orally administered Lactobacillus casei 5s significantly decreased the elevated total serum cholesterol and triglycerides, and attenuated macro vesicular steatosis in the liver. Moreover, Lactobacillus casei 5s improved the intestinal microbial balance in favour of lactobacilli, while decreasing the number of Escherichia coli cells. The bacteria were re-isolated and identified from the surface of the intestinal mucosa and from the faecal samples of treated animals, indicating adhesiveness and colonisation ability. The results of an acute oral toxicity study in mice and the absence of translocation to other organs demonstrated the safety of the strain. In conclusion, Lactobacillus casei 5s demonstrated promising probiotic potential and might be a good candidate for more detailed investigations.",
publisher = "Wageningen Academic Publishers, Wageningen",
journal = "Beneficial Microbes",
title = "Characterisation and preliminary lipid-lowering evaluation of Lactobacillus isolated from a traditional Serbian dairy product",
pages = "128-119",
number = "1",
volume = "6",
doi = "10.3920/BM2014.0018"
}

Zavisić, G., Ristić, S., Petricević, S., Jovanović, J. N., Radulović, Z., Petković, B. J., Strahinić, I.,& Piperski, V.. (2015). Characterisation and preliminary lipid-lowering evaluation of Lactobacillus isolated from a traditional Serbian dairy product. in Beneficial Microbes
Wageningen Academic Publishers, Wageningen., 6(1), 119-128.
https://doi.org/10.3920/BM2014.0018

Zavisić G, Ristić S, Petricević S, Jovanović JN, Radulović Z, Petković BJ, Strahinić I, Piperski V. Characterisation and preliminary lipid-lowering evaluation of Lactobacillus isolated from a traditional Serbian dairy product. in Beneficial Microbes. 2015;6(1):119-128.
doi:10.3920/BM2014.0018 .

Zavisić, G., Ristić, S., Petricević, S., Jovanović, J. Novakovic, Radulović, Z., Petković, B. Janac, Strahinić, Ivana, Piperski, V., "Characterisation and preliminary lipid-lowering evaluation of Lactobacillus isolated from a traditional Serbian dairy product" in Beneficial Microbes, 6, no. 1 (2015):119-128,
https://doi.org/10.3920/BM2014.0018 . .

TY  - JOUR
AU  - Radojković, M.
AU  - Ristić, S.
AU  - Pavlović, Sonja
AU  - Colović, M.
PY  - 2009
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/388
AB  - An atypical case of Philadelphia (Ph) negative, e1a2 BCR-ABL transcript positive chronic myeloid leukemia (CML) characterized with cyclic periodic leukocytosis and spontaneous remissions is reported. The patient was treated with imatinib and good hematology response with molecular remission was achieved. So far, only few Ph positive CML patients expressing p190 BCR-ABL protein and different clinical characteristics and treatment have been described in the literature. This is the first report of Philadelphia negative, p190 BCR-ABL positive CML with cyclic spontaneous oscillation of white blood cell count (WBC), and excellent response to imatinib treatment.
T2  - Leukemia Research
T1  - Molecular response to imatinib in patient with Ph negative p190 BCR-ABL transcript positive chronic myeloid leukemia with cyclic leukocytosis
EP  - e12
IS  - 6
SP  - e10
VL  - 33
DO  - 10.1016/j.leukres.2008.10.028
ER  - 

@article{
author = "Radojković, M. and Ristić, S. and Pavlović, Sonja and Colović, M.",
year = "2009",
abstract = "An atypical case of Philadelphia (Ph) negative, e1a2 BCR-ABL transcript positive chronic myeloid leukemia (CML) characterized with cyclic periodic leukocytosis and spontaneous remissions is reported. The patient was treated with imatinib and good hematology response with molecular remission was achieved. So far, only few Ph positive CML patients expressing p190 BCR-ABL protein and different clinical characteristics and treatment have been described in the literature. This is the first report of Philadelphia negative, p190 BCR-ABL positive CML with cyclic spontaneous oscillation of white blood cell count (WBC), and excellent response to imatinib treatment.",
journal = "Leukemia Research",
title = "Molecular response to imatinib in patient with Ph negative p190 BCR-ABL transcript positive chronic myeloid leukemia with cyclic leukocytosis",
pages = "e12-e10",
number = "6",
volume = "33",
doi = "10.1016/j.leukres.2008.10.028"
}

Radojković, M., Ristić, S., Pavlović, S.,& Colović, M.. (2009). Molecular response to imatinib in patient with Ph negative p190 BCR-ABL transcript positive chronic myeloid leukemia with cyclic leukocytosis. in Leukemia Research, 33(6), e10-e12.
https://doi.org/10.1016/j.leukres.2008.10.028

Radojković M, Ristić S, Pavlović S, Colović M. Molecular response to imatinib in patient with Ph negative p190 BCR-ABL transcript positive chronic myeloid leukemia with cyclic leukocytosis. in Leukemia Research. 2009;33(6):e10-e12.
doi:10.1016/j.leukres.2008.10.028 .

Radojković, M., Ristić, S., Pavlović, Sonja, Colović, M., "Molecular response to imatinib in patient with Ph negative p190 BCR-ABL transcript positive chronic myeloid leukemia with cyclic leukocytosis" in Leukemia Research, 33, no. 6 (2009):e10-e12,
https://doi.org/10.1016/j.leukres.2008.10.028 . .