TY  - CONF
AU  - Banović Đeri, Bojana
AU  - Vidanović, Dejan
AU  - Bojana, Tešović
AU  - Petrović, Tamaš
AU  - Ristić, Danijela
AU  - Vučurović, Ivan
AU  - Dudić, Dragana
PY  - 2021
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1869
AB  - Positively oriented single stranded RNA viruses [ssRNA(+)] persistently affect health and well-being of all
eukaryotes, including plants, animals and humans (i.e. SARS-CoV-2, yellow fever, hepatitis C, zika, West Nile,
pepper mild mottle virus, etc.). How come these viruses are so wide spread and hard to eradicate? Besides
their high changeability, another major reason is their ability to mimic host processes upon entering the host.
Only recently it was revealed that ssRNA(+) viruses undergo methylation inside the host in the process that
is similar to the methylation of the hosts’ own mRNAs. Such process may enable or disable virus to avoid
some of the host’s defense mechanisms, but it inevitably impacts viral stability and fitness.
Studies on this topic have only started, opening even more questions, with major ones being: how ssRNA(+)
methylation, that occurs in the host, impacts viral pathogenicity and are these methylation patterns different
in different hosts and for different ssRNA(+) viruses or do these viral methylomes share more universal
pattern in concordance with their similar genome organization? Among numerous different methylation
patterns of RNA, this research focused on N6-methyladenosine (m6A), as the most common and abundant
methylation in eukaryotes, which was confirmed to be present in ssRNA(+) viruses as well.
This study searched for patterns in the primary sequences and secondary structures of ssRNA(+) that are
associated to m6A methylation sites relying on the experimentally obtained m6A datasets for eukaryotes and
eukaryotic ssRNA(+) viruses. The results are discussed in view of datasets characteristics and study approach.
PB  - Novi Sad : Faculty of Sciences, Department of Biology and Ecology
C3  - Biologia Serbica
T1  - Bioinformatics analysis of eukaryotic positively oriented single stranded RNA viruses
IS  - 1 (Special Edition)
SP  - 29
VL  - 43
UR  - https://hdl.handle.net/21.15107/rcub_imagine_1869
ER  - 

@conference{
author = "Banović Đeri, Bojana and Vidanović, Dejan and Bojana, Tešović and Petrović, Tamaš and Ristić, Danijela and Vučurović, Ivan and Dudić, Dragana",
year = "2021",
abstract = "Positively oriented single stranded RNA viruses [ssRNA(+)] persistently affect health and well-being of all
eukaryotes, including plants, animals and humans (i.e. SARS-CoV-2, yellow fever, hepatitis C, zika, West Nile,
pepper mild mottle virus, etc.). How come these viruses are so wide spread and hard to eradicate? Besides
their high changeability, another major reason is their ability to mimic host processes upon entering the host.
Only recently it was revealed that ssRNA(+) viruses undergo methylation inside the host in the process that
is similar to the methylation of the hosts’ own mRNAs. Such process may enable or disable virus to avoid
some of the host’s defense mechanisms, but it inevitably impacts viral stability and fitness.
Studies on this topic have only started, opening even more questions, with major ones being: how ssRNA(+)
methylation, that occurs in the host, impacts viral pathogenicity and are these methylation patterns different
in different hosts and for different ssRNA(+) viruses or do these viral methylomes share more universal
pattern in concordance with their similar genome organization? Among numerous different methylation
patterns of RNA, this research focused on N6-methyladenosine (m6A), as the most common and abundant
methylation in eukaryotes, which was confirmed to be present in ssRNA(+) viruses as well.
This study searched for patterns in the primary sequences and secondary structures of ssRNA(+) that are
associated to m6A methylation sites relying on the experimentally obtained m6A datasets for eukaryotes and
eukaryotic ssRNA(+) viruses. The results are discussed in view of datasets characteristics and study approach.",
publisher = "Novi Sad : Faculty of Sciences, Department of Biology and Ecology",
journal = "Biologia Serbica",
title = "Bioinformatics analysis of eukaryotic positively oriented single stranded RNA viruses",
number = "1 (Special Edition)",
pages = "29",
volume = "43",
url = "https://hdl.handle.net/21.15107/rcub_imagine_1869"
}

Banović Đeri, B., Vidanović, D., Bojana, T., Petrović, T., Ristić, D., Vučurović, I.,& Dudić, D.. (2021). Bioinformatics analysis of eukaryotic positively oriented single stranded RNA viruses. in Biologia Serbica
Novi Sad : Faculty of Sciences, Department of Biology and Ecology., 43(1 (Special Edition)), 29.
https://hdl.handle.net/21.15107/rcub_imagine_1869

Banović Đeri B, Vidanović D, Bojana T, Petrović T, Ristić D, Vučurović I, Dudić D. Bioinformatics analysis of eukaryotic positively oriented single stranded RNA viruses. in Biologia Serbica. 2021;43(1 (Special Edition)):29.
https://hdl.handle.net/21.15107/rcub_imagine_1869 .

Banović Đeri, Bojana, Vidanović, Dejan, Bojana, Tešović, Petrović, Tamaš, Ristić, Danijela, Vučurović, Ivan, Dudić, Dragana, "Bioinformatics analysis of eukaryotic positively oriented single stranded RNA viruses" in Biologia Serbica, 43, no. 1 (Special Edition) (2021):29,
https://hdl.handle.net/21.15107/rcub_imagine_1869 .