TY  - JOUR
AU  - Mitrović, Aleksandra
AU  - Milovanović, Jelena
AU  - Gurgul, Jacek
AU  - Žekić, Andrijana
AU  - Nikodinović-Runić, Jasmina
AU  - Maslak, Veselin
PY  - 2023
UR  - https://www.sciencedirect.com/science/article/pii/S0141022923001011
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1984
AB  - We present a novel approach for the enzymatic functionalization of graphene, utilizing horseradish peroxidase (HPO) and laccase (LC) from Trametes versicolor. This study demonstrates, for the first time, the covalent modification of non-homogeneous graphene with a low surface-to-volume ratio, both in solution and on solid support. Through thermogravimetry analysis, we estimate the degree of functionalization to be 11% with HPO and 4% with LC, attributed to the varying redox potentials of the enzymes. This work highlights the potential of enzymatic reactions for tailored functionalization of graphene under mild conditions.
PB  - Elsevier
T2  - Enzyme and Microbial Technology
T1  - Enzymatic functionalization of liquid phase exfoliated graphene using horseradish peroxidase and laccase
SP  - 110293
VL  - 170
DO  - 10.1016/j.enzmictec.2023.110293
ER  - 

@article{
author = "Mitrović, Aleksandra and Milovanović, Jelena and Gurgul, Jacek and Žekić, Andrijana and Nikodinović-Runić, Jasmina and Maslak, Veselin",
year = "2023",
abstract = "We present a novel approach for the enzymatic functionalization of graphene, utilizing horseradish peroxidase (HPO) and laccase (LC) from Trametes versicolor. This study demonstrates, for the first time, the covalent modification of non-homogeneous graphene with a low surface-to-volume ratio, both in solution and on solid support. Through thermogravimetry analysis, we estimate the degree of functionalization to be 11% with HPO and 4% with LC, attributed to the varying redox potentials of the enzymes. This work highlights the potential of enzymatic reactions for tailored functionalization of graphene under mild conditions.",
publisher = "Elsevier",
journal = "Enzyme and Microbial Technology",
title = "Enzymatic functionalization of liquid phase exfoliated graphene using horseradish peroxidase and laccase",
pages = "110293",
volume = "170",
doi = "10.1016/j.enzmictec.2023.110293"
}

Mitrović, A., Milovanović, J., Gurgul, J., Žekić, A., Nikodinović-Runić, J.,& Maslak, V.. (2023). Enzymatic functionalization of liquid phase exfoliated graphene using horseradish peroxidase and laccase. in Enzyme and Microbial Technology
Elsevier., 170, 110293.
https://doi.org/10.1016/j.enzmictec.2023.110293

Mitrović A, Milovanović J, Gurgul J, Žekić A, Nikodinović-Runić J, Maslak V. Enzymatic functionalization of liquid phase exfoliated graphene using horseradish peroxidase and laccase. in Enzyme and Microbial Technology. 2023;170:110293.
doi:10.1016/j.enzmictec.2023.110293 .

Mitrović, Aleksandra, Milovanović, Jelena, Gurgul, Jacek, Žekić, Andrijana, Nikodinović-Runić, Jasmina, Maslak, Veselin, "Enzymatic functionalization of liquid phase exfoliated graphene using horseradish peroxidase and laccase" in Enzyme and Microbial Technology, 170 (2023):110293,
https://doi.org/10.1016/j.enzmictec.2023.110293 . .

TY  - JOUR
AU  - Lippert, Rainer
AU  - Vojnović, Sandra
AU  - Mitrović, Aleksandra
AU  - Jux, Norbert
AU  - Ivanović-Burmazović, Ivana
AU  - Vasiljević, Branka
AU  - Stanković, Nada
PY  - 2014
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/705
AB  - Ferrocene-substituted porphyrin RL-91 exhibits antifungal activity against opportune human pathogen Candida albicans. RL-91 efficiently inhibits growth of both planktonic C albicans cells and cells within biofilms without photoactivation. The minimal inhibitory concentration for plankton form (PMIC) was established to be 100 mu g/mL and the same concentration killed 80% of sessile cells in the mature biofilm (SMIC80). Furthermore PMIC of RL-91 efficiently prevents C albicans biofilm formation. RL-91 is cytotoxic for human fibroblasts in vitro in concentration of 10 mu g/mL, however it does not cause hemolysis in concentrations of up to 50 mu g/mL. These findings open possibility for application of RL-91 as an antifungal agent for external antibiofilm treatment of medical devices as well as a scaffold for further development of porphyrin based systemic antifungals.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Bioorganic & Medicinal Chemistry Letters
T1  - Effect of ferrocene-substituted porphyrin RL-91 on Candida albicans biofilm formation
EP  - 3511
IS  - 15
SP  - 3506
VL  - 24
DO  - 10.1016/j.bmcl.2014.05.061
ER  - 

@article{
author = "Lippert, Rainer and Vojnović, Sandra and Mitrović, Aleksandra and Jux, Norbert and Ivanović-Burmazović, Ivana and Vasiljević, Branka and Stanković, Nada",
year = "2014",
abstract = "Ferrocene-substituted porphyrin RL-91 exhibits antifungal activity against opportune human pathogen Candida albicans. RL-91 efficiently inhibits growth of both planktonic C albicans cells and cells within biofilms without photoactivation. The minimal inhibitory concentration for plankton form (PMIC) was established to be 100 mu g/mL and the same concentration killed 80% of sessile cells in the mature biofilm (SMIC80). Furthermore PMIC of RL-91 efficiently prevents C albicans biofilm formation. RL-91 is cytotoxic for human fibroblasts in vitro in concentration of 10 mu g/mL, however it does not cause hemolysis in concentrations of up to 50 mu g/mL. These findings open possibility for application of RL-91 as an antifungal agent for external antibiofilm treatment of medical devices as well as a scaffold for further development of porphyrin based systemic antifungals.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Bioorganic & Medicinal Chemistry Letters",
title = "Effect of ferrocene-substituted porphyrin RL-91 on Candida albicans biofilm formation",
pages = "3511-3506",
number = "15",
volume = "24",
doi = "10.1016/j.bmcl.2014.05.061"
}

Lippert, R., Vojnović, S., Mitrović, A., Jux, N., Ivanović-Burmazović, I., Vasiljević, B.,& Stanković, N.. (2014). Effect of ferrocene-substituted porphyrin RL-91 on Candida albicans biofilm formation. in Bioorganic & Medicinal Chemistry Letters
Pergamon-Elsevier Science Ltd, Oxford., 24(15), 3506-3511.
https://doi.org/10.1016/j.bmcl.2014.05.061

Lippert R, Vojnović S, Mitrović A, Jux N, Ivanović-Burmazović I, Vasiljević B, Stanković N. Effect of ferrocene-substituted porphyrin RL-91 on Candida albicans biofilm formation. in Bioorganic & Medicinal Chemistry Letters. 2014;24(15):3506-3511.
doi:10.1016/j.bmcl.2014.05.061 .

Lippert, Rainer, Vojnović, Sandra, Mitrović, Aleksandra, Jux, Norbert, Ivanović-Burmazović, Ivana, Vasiljević, Branka, Stanković, Nada, "Effect of ferrocene-substituted porphyrin RL-91 on Candida albicans biofilm formation" in Bioorganic & Medicinal Chemistry Letters, 24, no. 15 (2014):3506-3511,
https://doi.org/10.1016/j.bmcl.2014.05.061 . .