@article{
author = "Knezić, Z. and Nikčević, Gordana and Marjanović, J. and Glisin, V. and Popović, Z.",
year = "1993",
abstract = "A genomic fragment with the human β-interferon gene was cloned into a pL3-4, a defective Moloney murine leukemia virus (M-MuLV) vector. Here we show that clones selected after viral infection of mouse NIH 3T3 cells constitutively produced 128 IU/ml of human β-interferon. Constitutive synthesis of retroviral RNA was confirmed by dot blot hybridization of RNA isolated from two of the selected clones. Poly(I)·poly(C) and cycloheximide induction resulted in an increased RNA level, but this was not reflected in an increased production of biologically active interferon.",
journal = "Antiviral Research",
title = "Constitutive interferon expression from retroviral vector",
pages = "221-215",
number = "2-3",
volume = "22",
doi = "10.1016/0166-3542(93)90097-3"
}