TY  - JOUR
AU  - Stodulkova, Eva
AU  - Kuzma, Marek
AU  - Hench, Ivana Bratic
AU  - Cerny, Jan
AU  - Kralova, Jarmila
AU  - Novak, Petr
AU  - Chudickova, Milada
AU  - Savić, Miloje
AU  - Đokić, Lidija
AU  - Vasiljević, Branka
AU  - Flieger, Miroslav
PY  - 2011
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/492
AB  - A new polyene macrolide family, closely related to the pentaene macrolide antibiotic roflamycoin, was isolated from the both fermentation broth and biomass of Streptomyces durmitorensis wild-type strain MS405. The main compound was identified by NMR and Fourier transform ion cyclotron resonance mass spectrometry as 32,33-didehydroroflamycoin (1; DDHR). Additional four structurally related compounds were determined solely by MS analysis. DDHR induces cell death by apoptosis in various cancer cell lines as demonstrated by DNA fragmentation. Striking feature of DDHR is its internal fluorescence allowing visualization of labeled plasma membranes and internal membrane structures. The Journal of Antibiotics (2011) 64, 717-722; doi:10.1038/ja.2011.81; published online 14 September 2011
PB  - Nature Publishing Group, London
T2  - Journal of Antibiotics
T1  - New polyene macrolide family produced by submerged culture of Streptomyces durmitorensis
EP  - 722
IS  - 11
SP  - 717
VL  - 64
DO  - 10.1038/ja.2011.81
ER  - 

@article{
author = "Stodulkova, Eva and Kuzma, Marek and Hench, Ivana Bratic and Cerny, Jan and Kralova, Jarmila and Novak, Petr and Chudickova, Milada and Savić, Miloje and Đokić, Lidija and Vasiljević, Branka and Flieger, Miroslav",
year = "2011",
abstract = "A new polyene macrolide family, closely related to the pentaene macrolide antibiotic roflamycoin, was isolated from the both fermentation broth and biomass of Streptomyces durmitorensis wild-type strain MS405. The main compound was identified by NMR and Fourier transform ion cyclotron resonance mass spectrometry as 32,33-didehydroroflamycoin (1; DDHR). Additional four structurally related compounds were determined solely by MS analysis. DDHR induces cell death by apoptosis in various cancer cell lines as demonstrated by DNA fragmentation. Striking feature of DDHR is its internal fluorescence allowing visualization of labeled plasma membranes and internal membrane structures. The Journal of Antibiotics (2011) 64, 717-722; doi:10.1038/ja.2011.81; published online 14 September 2011",
publisher = "Nature Publishing Group, London",
journal = "Journal of Antibiotics",
title = "New polyene macrolide family produced by submerged culture of Streptomyces durmitorensis",
pages = "722-717",
number = "11",
volume = "64",
doi = "10.1038/ja.2011.81"
}

Stodulkova, E., Kuzma, M., Hench, I. B., Cerny, J., Kralova, J., Novak, P., Chudickova, M., Savić, M., Đokić, L., Vasiljević, B.,& Flieger, M.. (2011). New polyene macrolide family produced by submerged culture of Streptomyces durmitorensis. in Journal of Antibiotics
Nature Publishing Group, London., 64(11), 717-722.
https://doi.org/10.1038/ja.2011.81

Stodulkova E, Kuzma M, Hench IB, Cerny J, Kralova J, Novak P, Chudickova M, Savić M, Đokić L, Vasiljević B, Flieger M. New polyene macrolide family produced by submerged culture of Streptomyces durmitorensis. in Journal of Antibiotics. 2011;64(11):717-722.
doi:10.1038/ja.2011.81 .

Stodulkova, Eva, Kuzma, Marek, Hench, Ivana Bratic, Cerny, Jan, Kralova, Jarmila, Novak, Petr, Chudickova, Milada, Savić, Miloje, Đokić, Lidija, Vasiljević, Branka, Flieger, Miroslav, "New polyene macrolide family produced by submerged culture of Streptomyces durmitorensis" in Journal of Antibiotics, 64, no. 11 (2011):717-722,
https://doi.org/10.1038/ja.2011.81 . .