TY  - JOUR
AU  - Marković, Zoran
AU  - Mišović, Aleksandra
AU  - Zmejkoski, Danica
AU  - Zdravković, Nemanja
AU  - Kovač, Janez
AU  - Bajuk-Bogdanović, Danica
AU  - Milivojević, Dušan
AU  - Mojsin, Marija
AU  - Stevanović, Milena
AU  - Pavlović, Vladimir
AU  - Todorović Marković, Biljana
PY  - 2023
UR  - https://www.mdpi.com/2079-6382/12/5/919
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1892
AB  - Nowadays, it is a great challenge to develop new medicines for treating various infectious diseases. The treatment of these diseases is of utmost interest to further prevent the development of multi-drug resistance in different pathogens. Carbon quantum dots, as a new member of the carbon nanomaterials family, can potentially be used as a highly promising visible-light-triggered antibacterial agent. In this work, the results of antibacterial and cytotoxic activities of gamma-ray-irradiated carbon quantum dots are presented. Carbon quantum dots (CQDs) were synthesized from citric acid by a pyrolysis procedure and irradiated by gamma rays at different doses (25, 50, 100 and 200 kGy). Structure, chemical composition and optical properties were investigated by atomic force microscopy, transmission electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, Raman spectroscopy, UV-Vis spectrometry and photoluminescence. Structural analysis showed that CQDs have a spherical-like shape and dose-dependent average diameters and heights. Antibacterial tests showed that all irradiated dots had antibacterial activity but CQDs irradiated with dose of 100 kGy had antibacterial activity against all seven pathogen-reference bacterial strains. Gamma-ray-modified CQDs did not show any cytotoxicity toward human fetal-originated MRC-5 cells. Moreover, fluorescence microscopy showed excellent cellular uptake of CQDs irradiated with doses of 25 and 200 kGy into MRC-5 cells.
T2  - Antibiotics
T1  - Employing Gamma-Ray-Modified Carbon Quantum Dots to Combat a Wide Range of Bacteria
IS  - 5
SP  - 919
VL  - 12
DO  - 10.3390/antibiotics12050919
ER  - 

@article{
author = "Marković, Zoran and Mišović, Aleksandra and Zmejkoski, Danica and Zdravković, Nemanja and Kovač, Janez and Bajuk-Bogdanović, Danica and Milivojević, Dušan and Mojsin, Marija and Stevanović, Milena and Pavlović, Vladimir and Todorović Marković, Biljana",
year = "2023",
abstract = "Nowadays, it is a great challenge to develop new medicines for treating various infectious diseases. The treatment of these diseases is of utmost interest to further prevent the development of multi-drug resistance in different pathogens. Carbon quantum dots, as a new member of the carbon nanomaterials family, can potentially be used as a highly promising visible-light-triggered antibacterial agent. In this work, the results of antibacterial and cytotoxic activities of gamma-ray-irradiated carbon quantum dots are presented. Carbon quantum dots (CQDs) were synthesized from citric acid by a pyrolysis procedure and irradiated by gamma rays at different doses (25, 50, 100 and 200 kGy). Structure, chemical composition and optical properties were investigated by atomic force microscopy, transmission electron microscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, Raman spectroscopy, UV-Vis spectrometry and photoluminescence. Structural analysis showed that CQDs have a spherical-like shape and dose-dependent average diameters and heights. Antibacterial tests showed that all irradiated dots had antibacterial activity but CQDs irradiated with dose of 100 kGy had antibacterial activity against all seven pathogen-reference bacterial strains. Gamma-ray-modified CQDs did not show any cytotoxicity toward human fetal-originated MRC-5 cells. Moreover, fluorescence microscopy showed excellent cellular uptake of CQDs irradiated with doses of 25 and 200 kGy into MRC-5 cells.",
journal = "Antibiotics",
title = "Employing Gamma-Ray-Modified Carbon Quantum Dots to Combat a Wide Range of Bacteria",
number = "5",
pages = "919",
volume = "12",
doi = "10.3390/antibiotics12050919"
}

Marković, Z., Mišović, A., Zmejkoski, D., Zdravković, N., Kovač, J., Bajuk-Bogdanović, D., Milivojević, D., Mojsin, M., Stevanović, M., Pavlović, V.,& Todorović Marković, B.. (2023). Employing Gamma-Ray-Modified Carbon Quantum Dots to Combat a Wide Range of Bacteria. in Antibiotics, 12(5), 919.
https://doi.org/10.3390/antibiotics12050919

Marković Z, Mišović A, Zmejkoski D, Zdravković N, Kovač J, Bajuk-Bogdanović D, Milivojević D, Mojsin M, Stevanović M, Pavlović V, Todorović Marković B. Employing Gamma-Ray-Modified Carbon Quantum Dots to Combat a Wide Range of Bacteria. in Antibiotics. 2023;12(5):919.
doi:10.3390/antibiotics12050919 .

Marković, Zoran, Mišović, Aleksandra, Zmejkoski, Danica, Zdravković, Nemanja, Kovač, Janez, Bajuk-Bogdanović, Danica, Milivojević, Dušan, Mojsin, Marija, Stevanović, Milena, Pavlović, Vladimir, Todorović Marković, Biljana, "Employing Gamma-Ray-Modified Carbon Quantum Dots to Combat a Wide Range of Bacteria" in Antibiotics, 12, no. 5 (2023):919,
https://doi.org/10.3390/antibiotics12050919 . .

TY  - DATA
AU  - Marković, Zoran
AU  - Budimir, Milica
AU  - Danko, Martin
AU  - Milivojević, Dušan
AU  - Kubat, Pavel
AU  - Zmejkoski, Danica
AU  - Pavlović, Vladimir
AU  - Mojsin, Marija
AU  - Stevanović, Milena
AU  - Todorović Marković, Biljana
PY  - 2023
UR  - https://www.beilstein-journals.org/bjnano/articles/14/17
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1894
AB  - Figure S1: (a) TEM micrograph of CQDs, (b) top view AFM image of CQDs, (c) height profile of CQDs, and (d) particle size distribution of CQDs.
T2  - Beilstein Journal of Nanotechnology
T2  - Beilstein Journal of NanotechnologyBeilstein J. Nanotechnol.
T1  - Supplementary data for the article: Marković, Z., Budimir, M., Danko, M., Milivojević, D., Kubat, P., Zmejkoski, D., Pavlović, V., Mojsin, M., Stevanović, M.,& Todorović Marković, B.. (2023). Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine. in Beilstein Journal of Nanotechnology, 14(1), 165-174. https://doi.org/10.3762/bjnano.14.17
EP  - 174
IS  - 1
SP  - 165
VL  - 14
DO  - 10.3762/bjnano.14.17
ER  - 

@misc{
author = "Marković, Zoran and Budimir, Milica and Danko, Martin and Milivojević, Dušan and Kubat, Pavel and Zmejkoski, Danica and Pavlović, Vladimir and Mojsin, Marija and Stevanović, Milena and Todorović Marković, Biljana",
year = "2023",
abstract = "Figure S1: (a) TEM micrograph of CQDs, (b) top view AFM image of CQDs, (c) height profile of CQDs, and (d) particle size distribution of CQDs.",
journal = "Beilstein Journal of Nanotechnology, Beilstein Journal of NanotechnologyBeilstein J. Nanotechnol.",
title = "Supplementary data for the article: Marković, Z., Budimir, M., Danko, M., Milivojević, D., Kubat, P., Zmejkoski, D., Pavlović, V., Mojsin, M., Stevanović, M.,& Todorović Marković, B.. (2023). Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine. in Beilstein Journal of Nanotechnology, 14(1), 165-174. https://doi.org/10.3762/bjnano.14.17",
pages = "174-165",
number = "1",
volume = "14",
doi = "10.3762/bjnano.14.17"
}

Marković, Z., Budimir, M., Danko, M., Milivojević, D., Kubat, P., Zmejkoski, D., Pavlović, V., Mojsin, M., Stevanović, M.,& Todorović Marković, B.. (2023). Supplementary data for the article: Marković, Z., Budimir, M., Danko, M., Milivojević, D., Kubat, P., Zmejkoski, D., Pavlović, V., Mojsin, M., Stevanović, M.,& Todorović Marković, B.. (2023). Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine. in Beilstein Journal of Nanotechnology, 14(1), 165-174. https://doi.org/10.3762/bjnano.14.17. in Beilstein Journal of Nanotechnology, 14(1), 165-174.
https://doi.org/10.3762/bjnano.14.17

Marković Z, Budimir M, Danko M, Milivojević D, Kubat P, Zmejkoski D, Pavlović V, Mojsin M, Stevanović M, Todorović Marković B. Supplementary data for the article: Marković, Z., Budimir, M., Danko, M., Milivojević, D., Kubat, P., Zmejkoski, D., Pavlović, V., Mojsin, M., Stevanović, M.,& Todorović Marković, B.. (2023). Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine. in Beilstein Journal of Nanotechnology, 14(1), 165-174. https://doi.org/10.3762/bjnano.14.17. in Beilstein Journal of Nanotechnology. 2023;14(1):165-174.
doi:10.3762/bjnano.14.17 .

Marković, Zoran, Budimir, Milica, Danko, Martin, Milivojević, Dušan, Kubat, Pavel, Zmejkoski, Danica, Pavlović, Vladimir, Mojsin, Marija, Stevanović, Milena, Todorović Marković, Biljana, "Supplementary data for the article: Marković, Z., Budimir, M., Danko, M., Milivojević, D., Kubat, P., Zmejkoski, D., Pavlović, V., Mojsin, M., Stevanović, M.,& Todorović Marković, B.. (2023). Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine. in Beilstein Journal of Nanotechnology, 14(1), 165-174. https://doi.org/10.3762/bjnano.14.17" in Beilstein Journal of Nanotechnology, 14, no. 1 (2023):165-174,
https://doi.org/10.3762/bjnano.14.17 . .

TY  - JOUR
AU  - Marković, Zoran
AU  - Budimir, Milica
AU  - Danko, Martin
AU  - Milivojević, Dušan
AU  - Kubat, Pavel
AU  - Zmejkoski, Danica
AU  - Pavlović, Vladimir
AU  - Mojsin, Marija
AU  - Stevanović, Milena
AU  - Todorović Marković, Biljana
PY  - 2023
UR  - https://www.beilstein-journals.org/bjnano/articles/14/17
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1889
AB  - Carbon quantum dots as a novel type of carbon nanomaterials have attracted the attention of many researchers because of their
unique optical, antibacterial, and anticancer properties as well as their biocompatibility. In this study, for the first time, carbon
quantum dots were prepared from o-phenylenediamine dissolved in toluene by a solvothermal route. Subsequently, the prepared
carbon quantum dots were encapsulated into polyurethane films by a swelling–encapsulation–shrink method. Analyses of the
results obtained by different characterization methods (AFM, TEM, EDS, FTIR, photoluminescence, and EPR) indicate the significant influence of the precursor on structural, chemical, and optical properties. Antibacterial and cytotoxicity tests showed that these
dots did not have any antibacterial potential, because of the low extent of reactive oxygen species production, and showed low dark
cytotoxicity. By investigating the cellular uptake, it was established that these dots penetrated the HeLa cells and could be used as
probes for bioimaging.
T2  - Beilstein Journal of Nanotechnology
T2  - Beilstein Journal of NanotechnologyBeilstein J. Nanotechnol.
T1  - Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine
EP  - 174
IS  - 1
SP  - 165
VL  - 14
DO  - 10.3762/bjnano.14.17
ER  - 

@article{
author = "Marković, Zoran and Budimir, Milica and Danko, Martin and Milivojević, Dušan and Kubat, Pavel and Zmejkoski, Danica and Pavlović, Vladimir and Mojsin, Marija and Stevanović, Milena and Todorović Marković, Biljana",
year = "2023",
abstract = "Carbon quantum dots as a novel type of carbon nanomaterials have attracted the attention of many researchers because of their
unique optical, antibacterial, and anticancer properties as well as their biocompatibility. In this study, for the first time, carbon
quantum dots were prepared from o-phenylenediamine dissolved in toluene by a solvothermal route. Subsequently, the prepared
carbon quantum dots were encapsulated into polyurethane films by a swelling–encapsulation–shrink method. Analyses of the
results obtained by different characterization methods (AFM, TEM, EDS, FTIR, photoluminescence, and EPR) indicate the significant influence of the precursor on structural, chemical, and optical properties. Antibacterial and cytotoxicity tests showed that these
dots did not have any antibacterial potential, because of the low extent of reactive oxygen species production, and showed low dark
cytotoxicity. By investigating the cellular uptake, it was established that these dots penetrated the HeLa cells and could be used as
probes for bioimaging.",
journal = "Beilstein Journal of Nanotechnology, Beilstein Journal of NanotechnologyBeilstein J. Nanotechnol.",
title = "Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine",
pages = "174-165",
number = "1",
volume = "14",
doi = "10.3762/bjnano.14.17"
}

Marković, Z., Budimir, M., Danko, M., Milivojević, D., Kubat, P., Zmejkoski, D., Pavlović, V., Mojsin, M., Stevanović, M.,& Todorović Marković, B.. (2023). Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine. in Beilstein Journal of Nanotechnology, 14(1), 165-174.
https://doi.org/10.3762/bjnano.14.17

Marković Z, Budimir M, Danko M, Milivojević D, Kubat P, Zmejkoski D, Pavlović V, Mojsin M, Stevanović M, Todorović Marković B. Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine. in Beilstein Journal of Nanotechnology. 2023;14(1):165-174.
doi:10.3762/bjnano.14.17 .

Marković, Zoran, Budimir, Milica, Danko, Martin, Milivojević, Dušan, Kubat, Pavel, Zmejkoski, Danica, Pavlović, Vladimir, Mojsin, Marija, Stevanović, Milena, Todorović Marković, Biljana, "Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine" in Beilstein Journal of Nanotechnology, 14, no. 1 (2023):165-174,
https://doi.org/10.3762/bjnano.14.17 . .

TY  - DATA
AU  - Marković, Zoran
AU  - Mišović, Aleksandra
AU  - Zmejkoski, Danica
AU  - Zdravković, Nemanja
AU  - Kovač, Janez
AU  - Bajuk-Bogdanović, Danica
AU  - Milivojević, Dušan
AU  - Mojsin, Marija
AU  - Stevanović, Milena
AU  - Pavlović, Vladimir
AU  - Todorović Marković, Biljana
PY  - 2023
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1895
AB  - Figure S1. TEM micrographs a) CQD_25, b) CQD_50,c) CQD_100, and d) CQD_200 samples, respectively.
T2  - Antibiotics
T1  - Supplementary data for the article:Marković, Z., Mišović, A., Zmejkoski, D., Zdravković, N., Kovač, J., Bajuk-Bogdanović, D., Milivojević, D., Mojsin, M., Stevanović, M., Pavlović, V.,& Todorović Marković, B.. (2023). Employing Gamma-Ray-Modified Carbon Quantum Dots to Combat a Wide Range of Bacteria. in Antibiotics, 12(5), 919. https://doi.org/10.3390/antibiotics12050919
IS  - 5
SP  - 919
VL  - 12
UR  - https://hdl.handle.net/21.15107/rcub_imagine_1895
ER  - 

@misc{
author = "Marković, Zoran and Mišović, Aleksandra and Zmejkoski, Danica and Zdravković, Nemanja and Kovač, Janez and Bajuk-Bogdanović, Danica and Milivojević, Dušan and Mojsin, Marija and Stevanović, Milena and Pavlović, Vladimir and Todorović Marković, Biljana",
year = "2023",
abstract = "Figure S1. TEM micrographs a) CQD_25, b) CQD_50,c) CQD_100, and d) CQD_200 samples, respectively.",
journal = "Antibiotics",
title = "Supplementary data for the article:Marković, Z., Mišović, A., Zmejkoski, D., Zdravković, N., Kovač, J., Bajuk-Bogdanović, D., Milivojević, D., Mojsin, M., Stevanović, M., Pavlović, V.,& Todorović Marković, B.. (2023). Employing Gamma-Ray-Modified Carbon Quantum Dots to Combat a Wide Range of Bacteria. in Antibiotics, 12(5), 919. https://doi.org/10.3390/antibiotics12050919",
number = "5",
pages = "919",
volume = "12",
url = "https://hdl.handle.net/21.15107/rcub_imagine_1895"
}

Marković, Z., Mišović, A., Zmejkoski, D., Zdravković, N., Kovač, J., Bajuk-Bogdanović, D., Milivojević, D., Mojsin, M., Stevanović, M., Pavlović, V.,& Todorović Marković, B.. (2023). Supplementary data for the article:Marković, Z., Mišović, A., Zmejkoski, D., Zdravković, N., Kovač, J., Bajuk-Bogdanović, D., Milivojević, D., Mojsin, M., Stevanović, M., Pavlović, V.,& Todorović Marković, B.. (2023). Employing Gamma-Ray-Modified Carbon Quantum Dots to Combat a Wide Range of Bacteria. in Antibiotics, 12(5), 919. https://doi.org/10.3390/antibiotics12050919. in Antibiotics, 12(5), 919.
https://hdl.handle.net/21.15107/rcub_imagine_1895

Marković Z, Mišović A, Zmejkoski D, Zdravković N, Kovač J, Bajuk-Bogdanović D, Milivojević D, Mojsin M, Stevanović M, Pavlović V, Todorović Marković B. Supplementary data for the article:Marković, Z., Mišović, A., Zmejkoski, D., Zdravković, N., Kovač, J., Bajuk-Bogdanović, D., Milivojević, D., Mojsin, M., Stevanović, M., Pavlović, V.,& Todorović Marković, B.. (2023). Employing Gamma-Ray-Modified Carbon Quantum Dots to Combat a Wide Range of Bacteria. in Antibiotics, 12(5), 919. https://doi.org/10.3390/antibiotics12050919. in Antibiotics. 2023;12(5):919.
https://hdl.handle.net/21.15107/rcub_imagine_1895 .

Marković, Zoran, Mišović, Aleksandra, Zmejkoski, Danica, Zdravković, Nemanja, Kovač, Janez, Bajuk-Bogdanović, Danica, Milivojević, Dušan, Mojsin, Marija, Stevanović, Milena, Pavlović, Vladimir, Todorović Marković, Biljana, "Supplementary data for the article:Marković, Z., Mišović, A., Zmejkoski, D., Zdravković, N., Kovač, J., Bajuk-Bogdanović, D., Milivojević, D., Mojsin, M., Stevanović, M., Pavlović, V.,& Todorović Marković, B.. (2023). Employing Gamma-Ray-Modified Carbon Quantum Dots to Combat a Wide Range of Bacteria. in Antibiotics, 12(5), 919. https://doi.org/10.3390/antibiotics12050919" in Antibiotics, 12, no. 5 (2023):919,
https://hdl.handle.net/21.15107/rcub_imagine_1895 .

TY  - JOUR
AU  - Marković, Zoran M.
AU  - Kováčová, Mária
AU  - Jeremić, Sanja 
AU  - Nagy, Štefan
AU  - Milivojević, Dušan D.
AU  - Kubat, Pavel
AU  - Kleinová, Angela
AU  - Budimir, Milica D.
AU  - Mojsin, Marija
AU  - Stevanović, Milena 
AU  - Annušová, Adriana
AU  - Špitalský, Zdeno
AU  - Todorović Marković, Biljana M.
PY  - 2022
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1667
AB  - Development of new types of antimicrobial coatings is of utmost importance due to increasing problems with pathogen transmission from various infectious surfaces to human beings. In this study, new types of highly potent antimicrobial polyurethane composite films encapsulated by hydrophobic riboflavin-based carbon polymer dots are presented. Detailed structural, optical, antimicrobial, and cytotoxic investigations of these composites were conducted. Low-power blue light triggered the composites to eradicate Escherichia coli in 30 min, whereas the same effect toward Staphylococcus aureus was reached after 60 min. These composites also show low toxicity against MRC-5 cells. In this way, RF-CPD composites can be used for sterilization of highly touched objects in the healthcare industry.
T2  - Nanomaterials
T2  - Nanomaterials
T1  - Highly Efficient Antibacterial Polymer Composites Based on Hydrophobic Riboflavin Carbon Polymerized Dots
IS  - 22
SP  - 4070
VL  - 12
DO  - 10.3390/nano12224070
ER  - 

@article{
author = "Marković, Zoran M. and Kováčová, Mária and Jeremić, Sanja  and Nagy, Štefan and Milivojević, Dušan D. and Kubat, Pavel and Kleinová, Angela and Budimir, Milica D. and Mojsin, Marija and Stevanović, Milena  and Annušová, Adriana and Špitalský, Zdeno and Todorović Marković, Biljana M.",
year = "2022",
abstract = "Development of new types of antimicrobial coatings is of utmost importance due to increasing problems with pathogen transmission from various infectious surfaces to human beings. In this study, new types of highly potent antimicrobial polyurethane composite films encapsulated by hydrophobic riboflavin-based carbon polymer dots are presented. Detailed structural, optical, antimicrobial, and cytotoxic investigations of these composites were conducted. Low-power blue light triggered the composites to eradicate Escherichia coli in 30 min, whereas the same effect toward Staphylococcus aureus was reached after 60 min. These composites also show low toxicity against MRC-5 cells. In this way, RF-CPD composites can be used for sterilization of highly touched objects in the healthcare industry.",
journal = "Nanomaterials, Nanomaterials",
title = "Highly Efficient Antibacterial Polymer Composites Based on Hydrophobic Riboflavin Carbon Polymerized Dots",
number = "22",
pages = "4070",
volume = "12",
doi = "10.3390/nano12224070"
}

Marković, Z. M., Kováčová, M., Jeremić, S., Nagy, Š., Milivojević, D. D., Kubat, P., Kleinová, A., Budimir, M. D., Mojsin, M., Stevanović, M., Annušová, A., Špitalský, Z.,& Todorović Marković, B. M.. (2022). Highly Efficient Antibacterial Polymer Composites Based on Hydrophobic Riboflavin Carbon Polymerized Dots. in Nanomaterials, 12(22), 4070.
https://doi.org/10.3390/nano12224070

Marković ZM, Kováčová M, Jeremić S, Nagy Š, Milivojević DD, Kubat P, Kleinová A, Budimir MD, Mojsin M, Stevanović M, Annušová A, Špitalský Z, Todorović Marković BM. Highly Efficient Antibacterial Polymer Composites Based on Hydrophobic Riboflavin Carbon Polymerized Dots. in Nanomaterials. 2022;12(22):4070.
doi:10.3390/nano12224070 .

Marković, Zoran M., Kováčová, Mária, Jeremić, Sanja , Nagy, Štefan, Milivojević, Dušan D., Kubat, Pavel, Kleinová, Angela, Budimir, Milica D., Mojsin, Marija, Stevanović, Milena , Annušová, Adriana, Špitalský, Zdeno, Todorović Marković, Biljana M., "Highly Efficient Antibacterial Polymer Composites Based on Hydrophobic Riboflavin Carbon Polymerized Dots" in Nanomaterials, 12, no. 22 (2022):4070,
https://doi.org/10.3390/nano12224070 . .