TY  - CONF
AU  - Davidović, Slobodan
AU  - Stanković, Milica
AU  - Erić, Pavle
AU  - Erić, Katarina
PY  - 2023
UR  - https://belbi.bg.ac.rs/
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/2019
AB  - White-tailed eagle is the biggest bird of prey in Central and Southeast Europe. In Serbia
it inhabits the Vojvodina province and the valleys of Danube, Sava, Tisa and Tamiš.
Anthropogenic pressure on its habitats in Europe caused a decline in its numbers, but
due to the strict laws protecting both species and its habitats, birds’ numbers are now
steady and increasing. In Serbia, as a strictly protected species it is a subject of different
conservation programs. The available genetic data for this population are scarce and it
is necessary to assess its genetic diversity to improve the existing conservation efforts.
ND1 and Cytb mitochondrial genes can be used to estimate the populations’ adaptation to
different environmental conditions and their variability can potentially be used to evaluate
differentiation between populations.
To assess the genetic diversity of White-tailed eagle in Serbia we used mitochondrial ND1
and Cytb nucleotide sequences from 40 unrelated birds collected in nests. ND1 and Cytb
nucleotide sequences variability was evaluated using standard parameters of genetic
diversity (PGD). Acquired values were compared with the available data for the variability
of the D-loop region which showed that combined ND1/Cytb nucleotide sequences PGD
provide comparable results. Using publicly available sequences we reconstructed haplotype
networks for ND1, Cytb, ND1/Cytb and D-loop which further showed the applicability of ND1/
Cytb in population genetics analyses. Phylogeny reconstructed using combined ND1/Cytb
sequences identified two branches in Serbian white-tailed eagles. Although the majority of
substitutions were nonsynonymous, no selective pressure was detected.
Our data suggest that combined ND1/Cytb sequence variability provides sufficient
information to be used for population comparison, population differentiation analyses
and phylogeny reconstruction, but also gives a tool to potentially identify adaptations to
different environmental conditions.
PB  - Belgrade : Institute of molecular genetics and genetic engineering
C3  - 4th Belgrade Bioinformatics Conference
T1  - Evaluating ND1 and Cytb mitochondrial genes as markers for diversity analysis of protected White-tailed eagle species from Serbia
EP  - 79
SP  - 79
VL  - 4
UR  - https://hdl.handle.net/21.15107/rcub_imagine_2019
ER  - 

@conference{
author = "Davidović, Slobodan and Stanković, Milica and Erić, Pavle and Erić, Katarina",
year = "2023",
abstract = "White-tailed eagle is the biggest bird of prey in Central and Southeast Europe. In Serbia
it inhabits the Vojvodina province and the valleys of Danube, Sava, Tisa and Tamiš.
Anthropogenic pressure on its habitats in Europe caused a decline in its numbers, but
due to the strict laws protecting both species and its habitats, birds’ numbers are now
steady and increasing. In Serbia, as a strictly protected species it is a subject of different
conservation programs. The available genetic data for this population are scarce and it
is necessary to assess its genetic diversity to improve the existing conservation efforts.
ND1 and Cytb mitochondrial genes can be used to estimate the populations’ adaptation to
different environmental conditions and their variability can potentially be used to evaluate
differentiation between populations.
To assess the genetic diversity of White-tailed eagle in Serbia we used mitochondrial ND1
and Cytb nucleotide sequences from 40 unrelated birds collected in nests. ND1 and Cytb
nucleotide sequences variability was evaluated using standard parameters of genetic
diversity (PGD). Acquired values were compared with the available data for the variability
of the D-loop region which showed that combined ND1/Cytb nucleotide sequences PGD
provide comparable results. Using publicly available sequences we reconstructed haplotype
networks for ND1, Cytb, ND1/Cytb and D-loop which further showed the applicability of ND1/
Cytb in population genetics analyses. Phylogeny reconstructed using combined ND1/Cytb
sequences identified two branches in Serbian white-tailed eagles. Although the majority of
substitutions were nonsynonymous, no selective pressure was detected.
Our data suggest that combined ND1/Cytb sequence variability provides sufficient
information to be used for population comparison, population differentiation analyses
and phylogeny reconstruction, but also gives a tool to potentially identify adaptations to
different environmental conditions.",
publisher = "Belgrade : Institute of molecular genetics and genetic engineering",
journal = "4th Belgrade Bioinformatics Conference",
title = "Evaluating ND1 and Cytb mitochondrial genes as markers for diversity analysis of protected White-tailed eagle species from Serbia",
pages = "79-79",
volume = "4",
url = "https://hdl.handle.net/21.15107/rcub_imagine_2019"
}

Davidović, S., Stanković, M., Erić, P.,& Erić, K.. (2023). Evaluating ND1 and Cytb mitochondrial genes as markers for diversity analysis of protected White-tailed eagle species from Serbia. in 4th Belgrade Bioinformatics Conference
Belgrade : Institute of molecular genetics and genetic engineering., 4, 79-79.
https://hdl.handle.net/21.15107/rcub_imagine_2019

Davidović S, Stanković M, Erić P, Erić K. Evaluating ND1 and Cytb mitochondrial genes as markers for diversity analysis of protected White-tailed eagle species from Serbia. in 4th Belgrade Bioinformatics Conference. 2023;4:79-79.
https://hdl.handle.net/21.15107/rcub_imagine_2019 .

Davidović, Slobodan, Stanković, Milica, Erić, Pavle, Erić, Katarina, "Evaluating ND1 and Cytb mitochondrial genes as markers for diversity analysis of protected White-tailed eagle species from Serbia" in 4th Belgrade Bioinformatics Conference, 4 (2023):79-79,
https://hdl.handle.net/21.15107/rcub_imagine_2019 .

TY  - JOUR
AU  - Kloska, Anna
AU  - Giełczyk, Agata
AU  - Grzybowski, Tomasz
AU  - Płoski, Rafał
AU  - Kloska, Sylwester M.
AU  - Marciniak, Tomasz
AU  - Pałczyński, Krzysztof
AU  - Rogalla-Ładniak, Urszula
AU  - Malyarchuk, Boris A.
AU  - Derenko, Miroslava V.
AU  - Kovačević-Grujičić, Nataša
AU  - Stevanović, Milena
AU  - Drakulić, Danijela
AU  - Davidović, Slobodan
AU  - Spólnicka, Magdalena
AU  - Zubańska, Magdalena
AU  - Woźniak, Marcin
PY  - 2023
UR  - https://www.mdpi.com/1422-0067/24/20/15095
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/2171
AB  - Data obtained with the use of massive parallel sequencing (MPS) can be valuable in population genetics studies. In particular, such data harbor the potential for distinguishing samples from different populations, especially from those coming from adjacent populations of common origin. Machine learning (ML) techniques seem to be especially well suited for analyzing large datasets obtained using MPS. The Slavic populations constitute about a third of the population of Europe and inhabit a large area of the continent, while being relatively closely related in population genetics terms. In this proof-of-concept study, various ML techniques were used to classify DNA samples from Slavic and non-Slavic individuals. The primary objective of this study was to empirically evaluate the feasibility of discerning the genetic provenance of individuals of Slavic descent who exhibit genetic similarity, with the overarching goal of categorizing DNA specimens derived from diverse Slavic population representatives. Raw sequencing data were pre-processed, to obtain a 1200 character-long binary vector. A total of three classifiers were used—Random Forest, Support Vector Machine (SVM), and XGBoost. The most-promising results were obtained using SVM with a linear kernel, with 99.9% accuracy and F1-scores of 0.9846–1.000 for all classes.
T2  - International Journal of Molecular Sciences
T1  - A Machine-Learning-Based Approach to Prediction of Biogeographic Ancestry within Europe
IS  - 20
SP  - 15095
VL  - 24
DO  - 10.3390/ijms242015095
ER  - 

@article{
author = "Kloska, Anna and Giełczyk, Agata and Grzybowski, Tomasz and Płoski, Rafał and Kloska, Sylwester M. and Marciniak, Tomasz and Pałczyński, Krzysztof and Rogalla-Ładniak, Urszula and Malyarchuk, Boris A. and Derenko, Miroslava V. and Kovačević-Grujičić, Nataša and Stevanović, Milena and Drakulić, Danijela and Davidović, Slobodan and Spólnicka, Magdalena and Zubańska, Magdalena and Woźniak, Marcin",
year = "2023",
abstract = "Data obtained with the use of massive parallel sequencing (MPS) can be valuable in population genetics studies. In particular, such data harbor the potential for distinguishing samples from different populations, especially from those coming from adjacent populations of common origin. Machine learning (ML) techniques seem to be especially well suited for analyzing large datasets obtained using MPS. The Slavic populations constitute about a third of the population of Europe and inhabit a large area of the continent, while being relatively closely related in population genetics terms. In this proof-of-concept study, various ML techniques were used to classify DNA samples from Slavic and non-Slavic individuals. The primary objective of this study was to empirically evaluate the feasibility of discerning the genetic provenance of individuals of Slavic descent who exhibit genetic similarity, with the overarching goal of categorizing DNA specimens derived from diverse Slavic population representatives. Raw sequencing data were pre-processed, to obtain a 1200 character-long binary vector. A total of three classifiers were used—Random Forest, Support Vector Machine (SVM), and XGBoost. The most-promising results were obtained using SVM with a linear kernel, with 99.9% accuracy and F1-scores of 0.9846–1.000 for all classes.",
journal = "International Journal of Molecular Sciences",
title = "A Machine-Learning-Based Approach to Prediction of Biogeographic Ancestry within Europe",
number = "20",
pages = "15095",
volume = "24",
doi = "10.3390/ijms242015095"
}

Kloska, A., Giełczyk, A., Grzybowski, T., Płoski, R., Kloska, S. M., Marciniak, T., Pałczyński, K., Rogalla-Ładniak, U., Malyarchuk, B. A., Derenko, M. V., Kovačević-Grujičić, N., Stevanović, M., Drakulić, D., Davidović, S., Spólnicka, M., Zubańska, M.,& Woźniak, M.. (2023). A Machine-Learning-Based Approach to Prediction of Biogeographic Ancestry within Europe. in International Journal of Molecular Sciences, 24(20), 15095.
https://doi.org/10.3390/ijms242015095

Kloska A, Giełczyk A, Grzybowski T, Płoski R, Kloska SM, Marciniak T, Pałczyński K, Rogalla-Ładniak U, Malyarchuk BA, Derenko MV, Kovačević-Grujičić N, Stevanović M, Drakulić D, Davidović S, Spólnicka M, Zubańska M, Woźniak M. A Machine-Learning-Based Approach to Prediction of Biogeographic Ancestry within Europe. in International Journal of Molecular Sciences. 2023;24(20):15095.
doi:10.3390/ijms242015095 .

Kloska, Anna, Giełczyk, Agata, Grzybowski, Tomasz, Płoski, Rafał, Kloska, Sylwester M., Marciniak, Tomasz, Pałczyński, Krzysztof, Rogalla-Ładniak, Urszula, Malyarchuk, Boris A., Derenko, Miroslava V., Kovačević-Grujičić, Nataša, Stevanović, Milena, Drakulić, Danijela, Davidović, Slobodan, Spólnicka, Magdalena, Zubańska, Magdalena, Woźniak, Marcin, "A Machine-Learning-Based Approach to Prediction of Biogeographic Ancestry within Europe" in International Journal of Molecular Sciences, 24, no. 20 (2023):15095,
https://doi.org/10.3390/ijms242015095 . .

TY  - CHAP
AU  - Davidović, Slobodan
AU  - Aleksić, Jelena
AU  - Stevanović, Milena
AU  - Kovačević Grujičić, Nataša
PY  - 2023
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/2245
AB  - Mitohondrijska DNK (mtDNK) se odlikuje nizom osobina koje je čine pogodnom za istraživanja evolutivne
istorije ljudskih populacija koja se zasniva na molekularnim markerima ženske linije nasleđivanja. Tokom
poslednje decenije publikovano je više naučnih radova u kojima je analizirana varijabilnost mtDNK u populaciji
Srbije primenom markera različite rezolucije uključujući i kompletne genome. U skladu sa očekivanjima
zasnovanim na istorijskim, arheološkim i drugim izvorima koji govore u prilog veoma kompleksne
istorije populacija na Balkanskom poluostrvu, mtDNK podaci su potvrdili da se srpska populacija odlikuje
visokim nivoom raznovrsnosti mtDNK koji je posledica izuzetno složene dinamike ove populacije tokom
vremena. Današnji mtDNK profil populacije Srbije ne odstupa od matrilinealnog profila karakterističnog
za druge evropske populacije, a genetičke distance pokazuju da ova populacija zauzima centralnu poziciju
unutar grupe južnoslovenskih populacija koje se odlikuju visokom heterogenošću. Srpska populacija
deli najveći procenat mtDNK haplotipova sa geografski bliskim populacijama Balkanskog poluostrva koje
pripadaju južnoslovenskoj grupi, gde su uočeni i potencijalno privatni haplotipovi. Na osnovu filogenetske
i filogeografske analize kompletnih mitogenoma u srpskoj populaciji detektovane su retke mtDNK linije,
karakteristične za druge regione, poput Bliskog istoka (N1b, HV2), istočne Azije (D4) i Afrike (L2a1), kao i
one koje su potencijalno specifične za Balkansko poluostrvo, poput K1a13a1, U4c1b1 i H6a2b. Pored toga,
srpska populacija deli određeni broj mtDNK podhaplogrupa sa istočno- i zapadnoslovenskim populacijama
kao i sa germanskim populacijama severne i srednje Evrope. Istraživanja varijabilnosti mtDNK su pokazala
da se izuzetno velika raznovrsnost mtDNK savremene populacije Srbije može objasniti genetičkim doprinosom
kako slovenskih i germanskih, tako i pre-slovenskih populacija koje su naseljavale Balkansko poluostrvo
pre Velike seobe naroda.
AB  - The mitochondrial DNA (mtDNA) is characterized by a number of features that make it suitable for studying
the evolutionary history of human populations based on molecular markers with the female-specific
line of inheritance. During the last decade, several scientific papers were published in which the mtDNA
variability in the population of Serbia was analyzed using markers of different resolution including complete
mitogenomes. In accordance with expectations based on historical, archaeological and other sources
that speak in favor of a very complex history of populations on the Balkan Peninsula, mtDNA data confirmed
that Serbian population is characterized by a high level of mtDNA diversity, which is a consequence
of the exceptionally complex dynamics of this population over time. Today’s mtDNA profile of the Serbian
population does not differ from the matrilineal landscape characteristic of other European populations,
and according to genetic distances, this population occupies a central position within the group of South-
Slavic populations characterized by high heterogeneity. The Serbian population shares the highest percentage
of mtDNA haplotypes with the geographically close populations of the Balkan Peninsula
belonging to the South-Slavic group, where potentially private haplotypes were also observed. Phylogenetic
and phylogeographic analysis of complete mitogenomes in the Serbian population revealed rare
mtDNA lineages, characteristic of other regions, such as the Middle East (N1b, HV2), East Asia (D4) and
Africa (L2a1), as well as those that are potentially specific for Balkan Peninsula, like K1a13a1, U4c1b1 and
H6a2b. In addition, Serbian population shares a certain number of mtDNA subhaplogroups with East- and
West-Slavic populations as well as with the Germanic populations of Northern and Central Europe. Studies
of mtDNA variability have shown that the exceptionally high mtDNA diversity in contemporary Serbian
population may be associated with the genetic contribution of both Slavic and Germanic, as well as pre-
Slavic populations that inhabited the Balkan Peninsula before the Great Migration.
PB  - Beograd : Institut za molekularnu genetiku i genetičko inženjerstvo
T2  - Trendovi u molekularnoj Biologiji
T1  - Varijabilnost mitohondrijskog genskog pula stanovnika Republike Srbije
T1  - Mitochondrial gene pool variability of the residents of the Republic of Serbia
EP  - 36
IS  - 3
SP  - 18
UR  - https://hdl.handle.net/21.15107/rcub_imagine_2245
ER  - 

@inbook{
author = "Davidović, Slobodan and Aleksić, Jelena and Stevanović, Milena and Kovačević Grujičić, Nataša",
year = "2023",
abstract = "Mitohondrijska DNK (mtDNK) se odlikuje nizom osobina koje je čine pogodnom za istraživanja evolutivne
istorije ljudskih populacija koja se zasniva na molekularnim markerima ženske linije nasleđivanja. Tokom
poslednje decenije publikovano je više naučnih radova u kojima je analizirana varijabilnost mtDNK u populaciji
Srbije primenom markera različite rezolucije uključujući i kompletne genome. U skladu sa očekivanjima
zasnovanim na istorijskim, arheološkim i drugim izvorima koji govore u prilog veoma kompleksne
istorije populacija na Balkanskom poluostrvu, mtDNK podaci su potvrdili da se srpska populacija odlikuje
visokim nivoom raznovrsnosti mtDNK koji je posledica izuzetno složene dinamike ove populacije tokom
vremena. Današnji mtDNK profil populacije Srbije ne odstupa od matrilinealnog profila karakterističnog
za druge evropske populacije, a genetičke distance pokazuju da ova populacija zauzima centralnu poziciju
unutar grupe južnoslovenskih populacija koje se odlikuju visokom heterogenošću. Srpska populacija
deli najveći procenat mtDNK haplotipova sa geografski bliskim populacijama Balkanskog poluostrva koje
pripadaju južnoslovenskoj grupi, gde su uočeni i potencijalno privatni haplotipovi. Na osnovu filogenetske
i filogeografske analize kompletnih mitogenoma u srpskoj populaciji detektovane su retke mtDNK linije,
karakteristične za druge regione, poput Bliskog istoka (N1b, HV2), istočne Azije (D4) i Afrike (L2a1), kao i
one koje su potencijalno specifične za Balkansko poluostrvo, poput K1a13a1, U4c1b1 i H6a2b. Pored toga,
srpska populacija deli određeni broj mtDNK podhaplogrupa sa istočno- i zapadnoslovenskim populacijama
kao i sa germanskim populacijama severne i srednje Evrope. Istraživanja varijabilnosti mtDNK su pokazala
da se izuzetno velika raznovrsnost mtDNK savremene populacije Srbije može objasniti genetičkim doprinosom
kako slovenskih i germanskih, tako i pre-slovenskih populacija koje su naseljavale Balkansko poluostrvo
pre Velike seobe naroda., The mitochondrial DNA (mtDNA) is characterized by a number of features that make it suitable for studying
the evolutionary history of human populations based on molecular markers with the female-specific
line of inheritance. During the last decade, several scientific papers were published in which the mtDNA
variability in the population of Serbia was analyzed using markers of different resolution including complete
mitogenomes. In accordance with expectations based on historical, archaeological and other sources
that speak in favor of a very complex history of populations on the Balkan Peninsula, mtDNA data confirmed
that Serbian population is characterized by a high level of mtDNA diversity, which is a consequence
of the exceptionally complex dynamics of this population over time. Today’s mtDNA profile of the Serbian
population does not differ from the matrilineal landscape characteristic of other European populations,
and according to genetic distances, this population occupies a central position within the group of South-
Slavic populations characterized by high heterogeneity. The Serbian population shares the highest percentage
of mtDNA haplotypes with the geographically close populations of the Balkan Peninsula
belonging to the South-Slavic group, where potentially private haplotypes were also observed. Phylogenetic
and phylogeographic analysis of complete mitogenomes in the Serbian population revealed rare
mtDNA lineages, characteristic of other regions, such as the Middle East (N1b, HV2), East Asia (D4) and
Africa (L2a1), as well as those that are potentially specific for Balkan Peninsula, like K1a13a1, U4c1b1 and
H6a2b. In addition, Serbian population shares a certain number of mtDNA subhaplogroups with East- and
West-Slavic populations as well as with the Germanic populations of Northern and Central Europe. Studies
of mtDNA variability have shown that the exceptionally high mtDNA diversity in contemporary Serbian
population may be associated with the genetic contribution of both Slavic and Germanic, as well as pre-
Slavic populations that inhabited the Balkan Peninsula before the Great Migration.",
publisher = "Beograd : Institut za molekularnu genetiku i genetičko inženjerstvo",
journal = "Trendovi u molekularnoj Biologiji",
booktitle = "Varijabilnost mitohondrijskog genskog pula stanovnika Republike Srbije, Mitochondrial gene pool variability of the residents of the Republic of Serbia",
pages = "36-18",
number = "3",
url = "https://hdl.handle.net/21.15107/rcub_imagine_2245"
}

Davidović, S., Aleksić, J., Stevanović, M.,& Kovačević Grujičić, N.. (2023). Varijabilnost mitohondrijskog genskog pula stanovnika Republike Srbije. in Trendovi u molekularnoj Biologiji
Beograd : Institut za molekularnu genetiku i genetičko inženjerstvo.(3), 18-36.
https://hdl.handle.net/21.15107/rcub_imagine_2245

Davidović S, Aleksić J, Stevanović M, Kovačević Grujičić N. Varijabilnost mitohondrijskog genskog pula stanovnika Republike Srbije. in Trendovi u molekularnoj Biologiji. 2023;(3):18-36.
https://hdl.handle.net/21.15107/rcub_imagine_2245 .

Davidović, Slobodan, Aleksić, Jelena, Stevanović, Milena, Kovačević Grujičić, Nataša, "Varijabilnost mitohondrijskog genskog pula stanovnika Republike Srbije" in Trendovi u molekularnoj Biologiji, no. 3 (2023):18-36,
https://hdl.handle.net/21.15107/rcub_imagine_2245 .

TY  - JOUR
AU  - Holub, Karolina
AU  - Malyarchuk, Boris
AU  - Derenko, Miroslava
AU  - Kovačević-Grujičić, Nataša
AU  - Stevanović, Milena
AU  - Drakulić, Danijela
AU  - Davidović, Slobodan
AU  - Grzybowski, Tomasz
PY  - 2022
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1913
AB  - Genetic markers for the prediction of biogeographical ancestry have proved to be effective tools for law enforcement agencies for many years now. In this study, we attempted to assess the potential of insertion-deletion markers (InDel) and microsatellites (STRs) as subsidiary polymorphisms for inference of Slavic population ancestry. For that purpose, we genotyped Slavic-speaking populations samples from Belarus, the Czech Republic, Poland, Serbia, Ukraine and Russia in 46 InDels and 15 STRs by PCR and capillary electrophoresis and analyzed for between-population differentiation with the use of distance-based methods (FST, principal component analysis and multidimensional scaling).Additionally, we studied a sample from a Polish individual of well-documented genealogy whose biogeographic ancestry had previously been inferred by commercial genomic services using autosomal single nucleotide polymorphisms (SNPs), mitochondrial DNA and Y-SNP markers. For comparative purposes, we used genotype data collected in the “forInDel” browser and allele frequencies from previously published papers. The results obtained for InDels and STRs show that the Slavic populations constitute a genetically homogeneous group, with the exception of the Czechs differing clearly from the other tested populations. The analysis of the known Polish sample in the Snipper application proves the usefulness of the InDel markers on the continental level only. Conversely, microsatellites not only improve prediction, but are also informative if considered as an independent set of ancestry markers.
AB  - Markery genetyczne do przewidywania pochodzenia biogeograficznego od wielu lat okazują się skutecznymi narzędziami dla organów ścigania. W tym badaniu podjęliśmy próbę oceny potencjału markerów insercyjno-delecyjnych
(InDel) i mikrosatelitarnych (STR) jako pomocniczych polimorfizmów do wnioskowania o pochodzeniu populacji
słowiańskiej. W tym celu genotypowaliśmy próbki populacji słowiańskojęzycznych z Białorusi, Czech, Polski, Serbii,
Ukrainy i Rosji w w zakresie 46 markerów InDel oraz 15 loci STR za pomocą PCR i elektroforezy kapilarnej oraz
analizowaliśmy pod kątem różnicowania między populacjami za pomocą metod bazujących na dystansach genetycznych (FST, analiza głównych składowych i skalowanie wielowymiarowe). Dodatkowo zbadaliśmy próbkę mężczyzny
z populacji polskiej o dobrze udokumentowanej genealogii, którego pochodzenie biogeograficzne zostało wcześniej
ustalone przez komercyjne usługi genomiczne przy użyciu autosomalnych polimorfizmów pojedynczych nukleotydów (SNP), mitochondrialnego DNA i markerów Y-SNP. Do celów porównawczych wykorzystaliśmy dane genotypowe zebrane w przeglądarce „forInDel” i częstości alleli z wcześniej opublikowanych artykułów. Uzyskane wyniki
dla InDels i STR wskazują, że populacje słowiańskie stanowią grupę genetycznie jednorodną, z wyjątkiem Czechów
wyraźnie różniących się od pozostałych badanych populacji. Analiza znanej polskiej próbki w aplikacji Snipper
dowodzi przydatności markerów InDel jedynie na poziomie kontynentalnym. Z kolei, mikrosatelity nie tylko poprawiają wyniki predykcji, ale są informatywne jako niezależny zestaw markerów pochodzenia biogeograficznego.
PB  - Polish Society of Forensic Medicine and Criminology
T2  - Archives of Forensic Medicine and Criminology
T1  - Verification of insertion-deletion markers (InDels) and microsatellites (STRs) as subsidiary tools for inferring Slavic population ancestry
T1  - Weryfikacja markerów insercyjno-delecyjnych (InDels)
i mikrosatelitarnych (STR) jako narzędzi pomocniczych
do wnioskowania o pochodzeniu populacji słowiańskiej
EP  - 137
IS  - 3
SP  - 120
VL  - 72
DO  - 10.4467/16891716AMSIK.22.015.17393
ER  - 

@article{
author = "Holub, Karolina and Malyarchuk, Boris and Derenko, Miroslava and Kovačević-Grujičić, Nataša and Stevanović, Milena and Drakulić, Danijela and Davidović, Slobodan and Grzybowski, Tomasz",
year = "2022",
abstract = "Genetic markers for the prediction of biogeographical ancestry have proved to be effective tools for law enforcement agencies for many years now. In this study, we attempted to assess the potential of insertion-deletion markers (InDel) and microsatellites (STRs) as subsidiary polymorphisms for inference of Slavic population ancestry. For that purpose, we genotyped Slavic-speaking populations samples from Belarus, the Czech Republic, Poland, Serbia, Ukraine and Russia in 46 InDels and 15 STRs by PCR and capillary electrophoresis and analyzed for between-population differentiation with the use of distance-based methods (FST, principal component analysis and multidimensional scaling).Additionally, we studied a sample from a Polish individual of well-documented genealogy whose biogeographic ancestry had previously been inferred by commercial genomic services using autosomal single nucleotide polymorphisms (SNPs), mitochondrial DNA and Y-SNP markers. For comparative purposes, we used genotype data collected in the “forInDel” browser and allele frequencies from previously published papers. The results obtained for InDels and STRs show that the Slavic populations constitute a genetically homogeneous group, with the exception of the Czechs differing clearly from the other tested populations. The analysis of the known Polish sample in the Snipper application proves the usefulness of the InDel markers on the continental level only. Conversely, microsatellites not only improve prediction, but are also informative if considered as an independent set of ancestry markers., Markery genetyczne do przewidywania pochodzenia biogeograficznego od wielu lat okazują się skutecznymi narzędziami dla organów ścigania. W tym badaniu podjęliśmy próbę oceny potencjału markerów insercyjno-delecyjnych
(InDel) i mikrosatelitarnych (STR) jako pomocniczych polimorfizmów do wnioskowania o pochodzeniu populacji
słowiańskiej. W tym celu genotypowaliśmy próbki populacji słowiańskojęzycznych z Białorusi, Czech, Polski, Serbii,
Ukrainy i Rosji w w zakresie 46 markerów InDel oraz 15 loci STR za pomocą PCR i elektroforezy kapilarnej oraz
analizowaliśmy pod kątem różnicowania między populacjami za pomocą metod bazujących na dystansach genetycznych (FST, analiza głównych składowych i skalowanie wielowymiarowe). Dodatkowo zbadaliśmy próbkę mężczyzny
z populacji polskiej o dobrze udokumentowanej genealogii, którego pochodzenie biogeograficzne zostało wcześniej
ustalone przez komercyjne usługi genomiczne przy użyciu autosomalnych polimorfizmów pojedynczych nukleotydów (SNP), mitochondrialnego DNA i markerów Y-SNP. Do celów porównawczych wykorzystaliśmy dane genotypowe zebrane w przeglądarce „forInDel” i częstości alleli z wcześniej opublikowanych artykułów. Uzyskane wyniki
dla InDels i STR wskazują, że populacje słowiańskie stanowią grupę genetycznie jednorodną, z wyjątkiem Czechów
wyraźnie różniących się od pozostałych badanych populacji. Analiza znanej polskiej próbki w aplikacji Snipper
dowodzi przydatności markerów InDel jedynie na poziomie kontynentalnym. Z kolei, mikrosatelity nie tylko poprawiają wyniki predykcji, ale są informatywne jako niezależny zestaw markerów pochodzenia biogeograficznego.",
publisher = "Polish Society of Forensic Medicine and Criminology",
journal = "Archives of Forensic Medicine and Criminology",
title = "Verification of insertion-deletion markers (InDels) and microsatellites (STRs) as subsidiary tools for inferring Slavic population ancestry, Weryfikacja markerów insercyjno-delecyjnych (InDels)
i mikrosatelitarnych (STR) jako narzędzi pomocniczych
do wnioskowania o pochodzeniu populacji słowiańskiej",
pages = "137-120",
number = "3",
volume = "72",
doi = "10.4467/16891716AMSIK.22.015.17393"
}

Holub, K., Malyarchuk, B., Derenko, M., Kovačević-Grujičić, N., Stevanović, M., Drakulić, D., Davidović, S.,& Grzybowski, T.. (2022). Verification of insertion-deletion markers (InDels) and microsatellites (STRs) as subsidiary tools for inferring Slavic population ancestry. in Archives of Forensic Medicine and Criminology
Polish Society of Forensic Medicine and Criminology., 72(3), 120-137.
https://doi.org/10.4467/16891716AMSIK.22.015.17393

Holub K, Malyarchuk B, Derenko M, Kovačević-Grujičić N, Stevanović M, Drakulić D, Davidović S, Grzybowski T. Verification of insertion-deletion markers (InDels) and microsatellites (STRs) as subsidiary tools for inferring Slavic population ancestry. in Archives of Forensic Medicine and Criminology. 2022;72(3):120-137.
doi:10.4467/16891716AMSIK.22.015.17393 .

Holub, Karolina, Malyarchuk, Boris, Derenko, Miroslava, Kovačević-Grujičić, Nataša, Stevanović, Milena, Drakulić, Danijela, Davidović, Slobodan, Grzybowski, Tomasz, "Verification of insertion-deletion markers (InDels) and microsatellites (STRs) as subsidiary tools for inferring Slavic population ancestry" in Archives of Forensic Medicine and Criminology, 72, no. 3 (2022):120-137,
https://doi.org/10.4467/16891716AMSIK.22.015.17393 . .

TY  - JOUR
AU  - Davidović, Slobodan
AU  - Malyarchuk, Boris
AU  - Grzybowski, Tomasz
AU  - Aleksić, Jelena M.
AU  - Derenko, Miroslava
AU  - Litvinov, Andrey
AU  - Rogalla-Ladniak, Urszula
AU  - Stevanović, Milena
AU  - Kovačević Grujičić, Nataša
PY  - 2020
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1324
AB  - Mitochondrial genome (mtDNA) is a valuable resource in resolving various human forensic casework. The usage of variability of complete mtDNA genomes increases their discriminatory power to the maximum and enables ultimate resolution of distinct maternal lineages. However, their wider employment in forensic casework is nowadays limited by the lack of appropriate reference database. In order to fill in the gap in the reference data, which, considering Slavic-speaking populations, currently comprises only mitogenomes of East and West Slavs, we present mitogenome data for 226 Serbians, representatives of South Slavs from the Balkan Peninsula. We found 143 (sub)haplogroups among which West Eurasian ones were dominant. The percentage of unique haplotypes was 85%, and the random match probability was as low as 0.53%. We support previous findings on both high levels of genetic diversity in the Serbian population and patterns of genetic differentiation among this and ten studied European populations. However, our high-resolution data supported more pronounced genetic differentiation among Serbians and two Slavic populations (Russians and Poles) as well as expansion of the Serbian population after the Last Glacial Maximum and during the Migration period (fourth to ninth century A.D.), as inferred from the Bayesian skyline analysis. Phylogenetic analysis of haplotypes found in Serbians contributed towards the improvement of the worldwide mtDNA phylogeny, which is essential for the interpretation of the mtDNA casework.
PB  - New York : Springer
T2  - International Journal of Legal Medicine
T1  - Complete mitogenome data for the Serbian population: the contribution to high-quality forensic databases
EP  - 1590
IS  - 5
SP  - 1581
VL  - 134
DO  - 10.1007/s00414-020-02324-x
ER  - 

@article{
author = "Davidović, Slobodan and Malyarchuk, Boris and Grzybowski, Tomasz and Aleksić, Jelena M. and Derenko, Miroslava and Litvinov, Andrey and Rogalla-Ladniak, Urszula and Stevanović, Milena and Kovačević Grujičić, Nataša",
year = "2020",
abstract = "Mitochondrial genome (mtDNA) is a valuable resource in resolving various human forensic casework. The usage of variability of complete mtDNA genomes increases their discriminatory power to the maximum and enables ultimate resolution of distinct maternal lineages. However, their wider employment in forensic casework is nowadays limited by the lack of appropriate reference database. In order to fill in the gap in the reference data, which, considering Slavic-speaking populations, currently comprises only mitogenomes of East and West Slavs, we present mitogenome data for 226 Serbians, representatives of South Slavs from the Balkan Peninsula. We found 143 (sub)haplogroups among which West Eurasian ones were dominant. The percentage of unique haplotypes was 85%, and the random match probability was as low as 0.53%. We support previous findings on both high levels of genetic diversity in the Serbian population and patterns of genetic differentiation among this and ten studied European populations. However, our high-resolution data supported more pronounced genetic differentiation among Serbians and two Slavic populations (Russians and Poles) as well as expansion of the Serbian population after the Last Glacial Maximum and during the Migration period (fourth to ninth century A.D.), as inferred from the Bayesian skyline analysis. Phylogenetic analysis of haplotypes found in Serbians contributed towards the improvement of the worldwide mtDNA phylogeny, which is essential for the interpretation of the mtDNA casework.",
publisher = "New York : Springer",
journal = "International Journal of Legal Medicine",
title = "Complete mitogenome data for the Serbian population: the contribution to high-quality forensic databases",
pages = "1590-1581",
number = "5",
volume = "134",
doi = "10.1007/s00414-020-02324-x"
}

Davidović, S., Malyarchuk, B., Grzybowski, T., Aleksić, J. M., Derenko, M., Litvinov, A., Rogalla-Ladniak, U., Stevanović, M.,& Kovačević Grujičić, N.. (2020). Complete mitogenome data for the Serbian population: the contribution to high-quality forensic databases. in International Journal of Legal Medicine
New York : Springer., 134(5), 1581-1590.
https://doi.org/10.1007/s00414-020-02324-x

Davidović S, Malyarchuk B, Grzybowski T, Aleksić JM, Derenko M, Litvinov A, Rogalla-Ladniak U, Stevanović M, Kovačević Grujičić N. Complete mitogenome data for the Serbian population: the contribution to high-quality forensic databases. in International Journal of Legal Medicine. 2020;134(5):1581-1590.
doi:10.1007/s00414-020-02324-x .

Davidović, Slobodan, Malyarchuk, Boris, Grzybowski, Tomasz, Aleksić, Jelena M., Derenko, Miroslava, Litvinov, Andrey, Rogalla-Ladniak, Urszula, Stevanović, Milena, Kovačević Grujičić, Nataša, "Complete mitogenome data for the Serbian population: the contribution to high-quality forensic databases" in International Journal of Legal Medicine, 134, no. 5 (2020):1581-1590,
https://doi.org/10.1007/s00414-020-02324-x . .

TY  - JOUR
AU  - Stanisavljević Ninković, Danijela
AU  - Popović, Jelena
AU  - Petrović, Isidora
AU  - Davidović, Slobodan
AU  - Atkinson, Michael J.
AU  - Anastasov, Nataša
AU  - Stevanović, Milena
PY  - 2019
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1629
AB  - Purpose: Widespread medical use of radiation in diagnosis, imaging and treatment of different central nervous system malignancies lead to various consequences. Aim of this study was to further elucidate mechanism of cell response to radiation and possible consequence on neural differentiation. Materials and methods: NT2/D1 cells that resemble neural progenitors were used as a model system. Undifferentiated NT2/D1 cells and NT2/D1 cells in the early phase of neural differentiation were irradiated with low (0.2 Gy) and moderate (2 Gy) doses of gamma radiation. The effect was analyzed on apoptosis, cell cycle, senescence, spheroid formation and the expression of genes and miRNAs involved in the regulation of pluripotency or neural differentiation. Results: Two grays of irradiation induced apoptosis, senescence and cell cycle arrest of NT2/D1 cells, accompanied with altered expression of several genes (SOX2, OCT4, SOX3, PAX6) and miRNAs (miR-219, miR-21, miR124-a). Presented results show that 2 Gy of radiation significantly affected early phase of neural differentiation in vitro. Conclusions: These results suggest that 2 Gy of radiation significantly affected early phase of neural differentiation and affect the population of neural progenitors. These findings might help in better understanding of side effects of radiotherapy in treatments of central nervous system malignancies.
PB  - Taylor & Francis Ltd, Abingdon
T2  - International Journal of Radiation Biology
T1  - Radiation effects on early phase of NT2/D1 neural differentiation in vitro
EP  - 1639
IS  - 12
SP  - 1627
VL  - 95
DO  - 10.1080/09553002.2019.1665207
ER  - 

@article{
author = "Stanisavljević Ninković, Danijela and Popović, Jelena and Petrović, Isidora and Davidović, Slobodan and Atkinson, Michael J. and Anastasov, Nataša and Stevanović, Milena",
year = "2019",
abstract = "Purpose: Widespread medical use of radiation in diagnosis, imaging and treatment of different central nervous system malignancies lead to various consequences. Aim of this study was to further elucidate mechanism of cell response to radiation and possible consequence on neural differentiation. Materials and methods: NT2/D1 cells that resemble neural progenitors were used as a model system. Undifferentiated NT2/D1 cells and NT2/D1 cells in the early phase of neural differentiation were irradiated with low (0.2 Gy) and moderate (2 Gy) doses of gamma radiation. The effect was analyzed on apoptosis, cell cycle, senescence, spheroid formation and the expression of genes and miRNAs involved in the regulation of pluripotency or neural differentiation. Results: Two grays of irradiation induced apoptosis, senescence and cell cycle arrest of NT2/D1 cells, accompanied with altered expression of several genes (SOX2, OCT4, SOX3, PAX6) and miRNAs (miR-219, miR-21, miR124-a). Presented results show that 2 Gy of radiation significantly affected early phase of neural differentiation in vitro. Conclusions: These results suggest that 2 Gy of radiation significantly affected early phase of neural differentiation and affect the population of neural progenitors. These findings might help in better understanding of side effects of radiotherapy in treatments of central nervous system malignancies.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "International Journal of Radiation Biology",
title = "Radiation effects on early phase of NT2/D1 neural differentiation in vitro",
pages = "1639-1627",
number = "12",
volume = "95",
doi = "10.1080/09553002.2019.1665207"
}

Stanisavljević Ninković, D., Popović, J., Petrović, I., Davidović, S., Atkinson, M. J., Anastasov, N.,& Stevanović, M.. (2019). Radiation effects on early phase of NT2/D1 neural differentiation in vitro. in International Journal of Radiation Biology
Taylor & Francis Ltd, Abingdon., 95(12), 1627-1639.
https://doi.org/10.1080/09553002.2019.1665207

Stanisavljević Ninković D, Popović J, Petrović I, Davidović S, Atkinson MJ, Anastasov N, Stevanović M. Radiation effects on early phase of NT2/D1 neural differentiation in vitro. in International Journal of Radiation Biology. 2019;95(12):1627-1639.
doi:10.1080/09553002.2019.1665207 .

Stanisavljević Ninković, Danijela, Popović, Jelena, Petrović, Isidora, Davidović, Slobodan, Atkinson, Michael J., Anastasov, Nataša, Stevanović, Milena, "Radiation effects on early phase of NT2/D1 neural differentiation in vitro" in International Journal of Radiation Biology, 95, no. 12 (2019):1627-1639,
https://doi.org/10.1080/09553002.2019.1665207 . .

TY  - JOUR
AU  - Stanisavljević Ninković, Danijela
AU  - Popović, Jelena
AU  - Petrović, Isidora
AU  - Davidović, Slobodan
AU  - Atkinson, Michael J.
AU  - Anastasov, Nataša
AU  - Stevanović, Milena
PY  - 2019
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1206
AB  - Purpose: Widespread medical use of radiation in diagnosis, imaging and treatment of different central nervous system malignancies lead to various consequences. Aim of this study was to further elucidate mechanism of cell response to radiation and possible consequence on neural differentiation. Materials and methods: NT2/D1 cells that resemble neural progenitors were used as a model system. Undifferentiated NT2/D1 cells and NT2/D1 cells in the early phase of neural differentiation were irradiated with low (0.2 Gy) and moderate (2 Gy) doses of gamma radiation. The effect was analyzed on apoptosis, cell cycle, senescence, spheroid formation and the expression of genes and miRNAs involved in the regulation of pluripotency or neural differentiation. Results: Two grays of irradiation induced apoptosis, senescence and cell cycle arrest of NT2/D1 cells, accompanied with altered expression of several genes (SOX2, OCT4, SOX3, PAX6) and miRNAs (miR-219, miR-21, miR124-a). Presented results show that 2 Gy of radiation significantly affected early phase of neural differentiation in vitro. Conclusions: These results suggest that 2 Gy of radiation significantly affected early phase of neural differentiation and affect the population of neural progenitors. These findings might help in better understanding of side effects of radiotherapy in treatments of central nervous system malignancies.
PB  - Taylor & Francis Ltd, Abingdon
T2  - International Journal of Radiation Biology
T1  - Radiation effects on early phase of NT2/D1 neural differentiation in vitro
EP  - 1639
IS  - 12
SP  - 1627
VL  - 95
DO  - 10.1080/09553002.2019.1665207
ER  - 

@article{
author = "Stanisavljević Ninković, Danijela and Popović, Jelena and Petrović, Isidora and Davidović, Slobodan and Atkinson, Michael J. and Anastasov, Nataša and Stevanović, Milena",
year = "2019",
abstract = "Purpose: Widespread medical use of radiation in diagnosis, imaging and treatment of different central nervous system malignancies lead to various consequences. Aim of this study was to further elucidate mechanism of cell response to radiation and possible consequence on neural differentiation. Materials and methods: NT2/D1 cells that resemble neural progenitors were used as a model system. Undifferentiated NT2/D1 cells and NT2/D1 cells in the early phase of neural differentiation were irradiated with low (0.2 Gy) and moderate (2 Gy) doses of gamma radiation. The effect was analyzed on apoptosis, cell cycle, senescence, spheroid formation and the expression of genes and miRNAs involved in the regulation of pluripotency or neural differentiation. Results: Two grays of irradiation induced apoptosis, senescence and cell cycle arrest of NT2/D1 cells, accompanied with altered expression of several genes (SOX2, OCT4, SOX3, PAX6) and miRNAs (miR-219, miR-21, miR124-a). Presented results show that 2 Gy of radiation significantly affected early phase of neural differentiation in vitro. Conclusions: These results suggest that 2 Gy of radiation significantly affected early phase of neural differentiation and affect the population of neural progenitors. These findings might help in better understanding of side effects of radiotherapy in treatments of central nervous system malignancies.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "International Journal of Radiation Biology",
title = "Radiation effects on early phase of NT2/D1 neural differentiation in vitro",
pages = "1639-1627",
number = "12",
volume = "95",
doi = "10.1080/09553002.2019.1665207"
}

Stanisavljević Ninković, D., Popović, J., Petrović, I., Davidović, S., Atkinson, M. J., Anastasov, N.,& Stevanović, M.. (2019). Radiation effects on early phase of NT2/D1 neural differentiation in vitro. in International Journal of Radiation Biology
Taylor & Francis Ltd, Abingdon., 95(12), 1627-1639.
https://doi.org/10.1080/09553002.2019.1665207

Stanisavljević Ninković D, Popović J, Petrović I, Davidović S, Atkinson MJ, Anastasov N, Stevanović M. Radiation effects on early phase of NT2/D1 neural differentiation in vitro. in International Journal of Radiation Biology. 2019;95(12):1627-1639.
doi:10.1080/09553002.2019.1665207 .

Stanisavljević Ninković, Danijela, Popović, Jelena, Petrović, Isidora, Davidović, Slobodan, Atkinson, Michael J., Anastasov, Nataša, Stevanović, Milena, "Radiation effects on early phase of NT2/D1 neural differentiation in vitro" in International Journal of Radiation Biology, 95, no. 12 (2019):1627-1639,
https://doi.org/10.1080/09553002.2019.1665207 . .

TY  - JOUR
AU  - Tošić, Nataša
AU  - Petrović, Isidora
AU  - Kovačević Grujičić, Nataša
AU  - Davidović, Slobodan
AU  - Virijević, Marijana
AU  - Suvajdžić-Vuković, Nada
AU  - Pavlović, Sonja
AU  - Stevanović, Milena
PY  - 2018
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1196
AB  - Aberrant expression of different SOX (SRY-related high mobility group (HMG) box) genes has been observed in number of tumors but, little is known about their expression patterns in hematological malignancies, especially in acute myeloid leukemia (AML). In this study we investigated SOX2, SOX3, SOX11, SOX14 and SOX18 gene expression in 50 de novo adult AML patients and correlated our findings with known clinical and molecular prognostic markers of the disease. We have found that these genes are overexpressed in 10-22% of patients and preliminary findings suggest that high expression level of these genes may have prognostic significance in AML patients. This is the first study focused on examining the expression level of SOX2, SOX3, SOX11, SOX14 and SOX18 genes in AML patients. Although this is a relatively limited study, initial findings indicate the need for further investigation of these genes, their potential roles in leukemia pathogenesis as well as prognosis in AML patients.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Leukemia Research
T1  - Prognostic significance of SOX2, SOX3, SOX11, SOX14 and SOX18 gene expression in adult de novo acute myeloid leukemia
EP  - 38
SP  - 32
VL  - 67
DO  - 10.1016/j.leukres.2018.02.001
ER  - 

@article{
author = "Tošić, Nataša and Petrović, Isidora and Kovačević Grujičić, Nataša and Davidović, Slobodan and Virijević, Marijana and Suvajdžić-Vuković, Nada and Pavlović, Sonja and Stevanović, Milena",
year = "2018",
abstract = "Aberrant expression of different SOX (SRY-related high mobility group (HMG) box) genes has been observed in number of tumors but, little is known about their expression patterns in hematological malignancies, especially in acute myeloid leukemia (AML). In this study we investigated SOX2, SOX3, SOX11, SOX14 and SOX18 gene expression in 50 de novo adult AML patients and correlated our findings with known clinical and molecular prognostic markers of the disease. We have found that these genes are overexpressed in 10-22% of patients and preliminary findings suggest that high expression level of these genes may have prognostic significance in AML patients. This is the first study focused on examining the expression level of SOX2, SOX3, SOX11, SOX14 and SOX18 genes in AML patients. Although this is a relatively limited study, initial findings indicate the need for further investigation of these genes, their potential roles in leukemia pathogenesis as well as prognosis in AML patients.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Leukemia Research",
title = "Prognostic significance of SOX2, SOX3, SOX11, SOX14 and SOX18 gene expression in adult de novo acute myeloid leukemia",
pages = "38-32",
volume = "67",
doi = "10.1016/j.leukres.2018.02.001"
}

Tošić, N., Petrović, I., Kovačević Grujičić, N., Davidović, S., Virijević, M., Suvajdžić-Vuković, N., Pavlović, S.,& Stevanović, M.. (2018). Prognostic significance of SOX2, SOX3, SOX11, SOX14 and SOX18 gene expression in adult de novo acute myeloid leukemia. in Leukemia Research
Pergamon-Elsevier Science Ltd, Oxford., 67, 32-38.
https://doi.org/10.1016/j.leukres.2018.02.001

Tošić N, Petrović I, Kovačević Grujičić N, Davidović S, Virijević M, Suvajdžić-Vuković N, Pavlović S, Stevanović M. Prognostic significance of SOX2, SOX3, SOX11, SOX14 and SOX18 gene expression in adult de novo acute myeloid leukemia. in Leukemia Research. 2018;67:32-38.
doi:10.1016/j.leukres.2018.02.001 .

Tošić, Nataša, Petrović, Isidora, Kovačević Grujičić, Nataša, Davidović, Slobodan, Virijević, Marijana, Suvajdžić-Vuković, Nada, Pavlović, Sonja, Stevanović, Milena, "Prognostic significance of SOX2, SOX3, SOX11, SOX14 and SOX18 gene expression in adult de novo acute myeloid leukemia" in Leukemia Research, 67 (2018):32-38,
https://doi.org/10.1016/j.leukres.2018.02.001 . .

TY  - JOUR
AU  - Davidović, Slobodan
AU  - Malyarchuk, Boris
AU  - Aleksić, Jelena M.
AU  - Derenko, Miroslava
AU  - Topalović, Vladanka
AU  - Litvinov, Andrey
AU  - Skonieczna, Katarzyna
AU  - Rogalla, Urszula
AU  - Grzybowski, Tomasz
AU  - Stevanović, Milena
AU  - Kovačević Grujičić, Nataša
PY  - 2017
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1013
AB  - Background: Available mitochondrial (mtDNA) data demonstrate genetic differentiation among South Slavs inhabiting the Balkan Peninsula. However, their resolution is insufficient to elucidate the female-specific aspects of the genetic history of South Slavs, including the genetic impact of various migrations which were rather common within the Balkans, a region having a turbulent demographic history. Aim: The aim was to thoroughly study complete mitogenomes of Serbians, a population linking westward and eastward South Slavs. Subjects and methods: Forty-six predominantly Serbian super-haplogroup U complete mitogenomes were analysed phylogenetically against similar to 4000 available complete mtDNAs of modern and ancient Western Eurasians. Results: Serbians share a number of U mtDNA lineages with Southern, Eastern-Central and North-Western Europeans. Putative Balkan-specific lineages (e.g. U1a1c2, U4c1b1, U5b3j, K1a4l and K1a13a1) and lineages shared among Serbians (South Slavs) and West and East Slavs were detected (e.g. U2e1b1, U2e2a1d, U4a2a, U4a2c, U4a2g1, U4d2b and U5b1a1). Conclusion: The exceptional diversity of maternal lineages found in Serbians may be associated with the genetic impact of both autochthonous pre-Slavic Balkan populations whose mtDNA gene pool was affected by migrations of various populations over time (e.g. Bronze Age pastoralists) and Slavic and Germanic newcomers in the early Middle Ages.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Annals of Human Biology
T1  - Mitochondrial super-haplogroup U diversity in Serbians
EP  - 418
IS  - 5
SP  - 408
VL  - 44
DO  - 10.1080/03014460.2017.1287954
ER  - 

@article{
author = "Davidović, Slobodan and Malyarchuk, Boris and Aleksić, Jelena M. and Derenko, Miroslava and Topalović, Vladanka and Litvinov, Andrey and Skonieczna, Katarzyna and Rogalla, Urszula and Grzybowski, Tomasz and Stevanović, Milena and Kovačević Grujičić, Nataša",
year = "2017",
abstract = "Background: Available mitochondrial (mtDNA) data demonstrate genetic differentiation among South Slavs inhabiting the Balkan Peninsula. However, their resolution is insufficient to elucidate the female-specific aspects of the genetic history of South Slavs, including the genetic impact of various migrations which were rather common within the Balkans, a region having a turbulent demographic history. Aim: The aim was to thoroughly study complete mitogenomes of Serbians, a population linking westward and eastward South Slavs. Subjects and methods: Forty-six predominantly Serbian super-haplogroup U complete mitogenomes were analysed phylogenetically against similar to 4000 available complete mtDNAs of modern and ancient Western Eurasians. Results: Serbians share a number of U mtDNA lineages with Southern, Eastern-Central and North-Western Europeans. Putative Balkan-specific lineages (e.g. U1a1c2, U4c1b1, U5b3j, K1a4l and K1a13a1) and lineages shared among Serbians (South Slavs) and West and East Slavs were detected (e.g. U2e1b1, U2e2a1d, U4a2a, U4a2c, U4a2g1, U4d2b and U5b1a1). Conclusion: The exceptional diversity of maternal lineages found in Serbians may be associated with the genetic impact of both autochthonous pre-Slavic Balkan populations whose mtDNA gene pool was affected by migrations of various populations over time (e.g. Bronze Age pastoralists) and Slavic and Germanic newcomers in the early Middle Ages.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Annals of Human Biology",
title = "Mitochondrial super-haplogroup U diversity in Serbians",
pages = "418-408",
number = "5",
volume = "44",
doi = "10.1080/03014460.2017.1287954"
}

Davidović, S., Malyarchuk, B., Aleksić, J. M., Derenko, M., Topalović, V., Litvinov, A., Skonieczna, K., Rogalla, U., Grzybowski, T., Stevanović, M.,& Kovačević Grujičić, N.. (2017). Mitochondrial super-haplogroup U diversity in Serbians. in Annals of Human Biology
Taylor & Francis Ltd, Abingdon., 44(5), 408-418.
https://doi.org/10.1080/03014460.2017.1287954

Davidović S, Malyarchuk B, Aleksić JM, Derenko M, Topalović V, Litvinov A, Skonieczna K, Rogalla U, Grzybowski T, Stevanović M, Kovačević Grujičić N. Mitochondrial super-haplogroup U diversity in Serbians. in Annals of Human Biology. 2017;44(5):408-418.
doi:10.1080/03014460.2017.1287954 .

Davidović, Slobodan, Malyarchuk, Boris, Aleksić, Jelena M., Derenko, Miroslava, Topalović, Vladanka, Litvinov, Andrey, Skonieczna, Katarzyna, Rogalla, Urszula, Grzybowski, Tomasz, Stevanović, Milena, Kovačević Grujičić, Nataša, "Mitochondrial super-haplogroup U diversity in Serbians" in Annals of Human Biology, 44, no. 5 (2017):408-418,
https://doi.org/10.1080/03014460.2017.1287954 . .

TY  - JOUR
AU  - Stojković, Dejan S.
AU  - Kovačević Grujičić, Nataša
AU  - Reis, Filipa S.
AU  - Davidović, Slobodan
AU  - Barros, Lillian
AU  - Popović, Jelena
AU  - Petrović, Isidora
AU  - Pavić, Aleksandar
AU  - Glamoclija, Jasmina
AU  - Cirić, Ana
AU  - Stevanović, Milena
AU  - Ferreira, Isabel C. F. R.
AU  - Soković, Marina
PY  - 2017
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1051
AB  - Wild Meripilus giganteus Karst belongs to the order Polyporales, in which some members are known to possess a wide range of pharmacological properties. M. giganteus showed to be rich in carbohydrates (74.49 g/100 g) and proteins (15.94 g/100 g), presenting low fat content (1.51 g/100 g). Chemical composition was determined by using chromatographic techniques. Also, various bioactive compounds were detected including all four tocopherol isoforms with delta- and gamma-tocopherols being predominant (123.35 and 77.80 mu g/100 g, respectively); five organic acids (oxalic, malic, quinic, citric and fumaric acids) with predominant malic acid (3.17 g/100 g); and three phenolic acids and related compounds (p-hydroxybenzoic, p-coumaric and cinnamic acids; 1010, 2420 and 340 mu g/100 g, respectively). M. giganteus methanolic extract exhibited antioxidant activity tested by five different assays with the strongest potential in TBARS assay (EC50 0.31 mg/mL); and antimicrobial activities (MIC/MBC 0.0125-5 mg/mL; MIC/MFC 0.025-0.4 mg/mL). Furthermore, treatment of cervical carcinoma cell line (HeLa) led to reduction in cell's viability in MTT assay (lC(50) 0.41 mg/mL after 48 h), induced process of apoptosis and inhibited cell's migration in vitro. The analysed extract was not toxic for zebrafish embryos (at 0.5 mg/mL), indicating its biosafety and potential application as a dietary supplement in chemoprevention.
PB  - Elsevier Science Bv, Amsterdam
T2  - Lwt-Food Science and Technology
T1  - Chemical composition of the mushroom Meripilus giganteus Karst. and bioactive properties of its methanolic extract
EP  - 462
SP  - 454
VL  - 79
DO  - 10.1016/j.lwt.2017.01.045
ER  - 

@article{
author = "Stojković, Dejan S. and Kovačević Grujičić, Nataša and Reis, Filipa S. and Davidović, Slobodan and Barros, Lillian and Popović, Jelena and Petrović, Isidora and Pavić, Aleksandar and Glamoclija, Jasmina and Cirić, Ana and Stevanović, Milena and Ferreira, Isabel C. F. R. and Soković, Marina",
year = "2017",
abstract = "Wild Meripilus giganteus Karst belongs to the order Polyporales, in which some members are known to possess a wide range of pharmacological properties. M. giganteus showed to be rich in carbohydrates (74.49 g/100 g) and proteins (15.94 g/100 g), presenting low fat content (1.51 g/100 g). Chemical composition was determined by using chromatographic techniques. Also, various bioactive compounds were detected including all four tocopherol isoforms with delta- and gamma-tocopherols being predominant (123.35 and 77.80 mu g/100 g, respectively); five organic acids (oxalic, malic, quinic, citric and fumaric acids) with predominant malic acid (3.17 g/100 g); and three phenolic acids and related compounds (p-hydroxybenzoic, p-coumaric and cinnamic acids; 1010, 2420 and 340 mu g/100 g, respectively). M. giganteus methanolic extract exhibited antioxidant activity tested by five different assays with the strongest potential in TBARS assay (EC50 0.31 mg/mL); and antimicrobial activities (MIC/MBC 0.0125-5 mg/mL; MIC/MFC 0.025-0.4 mg/mL). Furthermore, treatment of cervical carcinoma cell line (HeLa) led to reduction in cell's viability in MTT assay (lC(50) 0.41 mg/mL after 48 h), induced process of apoptosis and inhibited cell's migration in vitro. The analysed extract was not toxic for zebrafish embryos (at 0.5 mg/mL), indicating its biosafety and potential application as a dietary supplement in chemoprevention.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Lwt-Food Science and Technology",
title = "Chemical composition of the mushroom Meripilus giganteus Karst. and bioactive properties of its methanolic extract",
pages = "462-454",
volume = "79",
doi = "10.1016/j.lwt.2017.01.045"
}

Stojković, D. S., Kovačević Grujičić, N., Reis, F. S., Davidović, S., Barros, L., Popović, J., Petrović, I., Pavić, A., Glamoclija, J., Cirić, A., Stevanović, M., Ferreira, I. C. F. R.,& Soković, M.. (2017). Chemical composition of the mushroom Meripilus giganteus Karst. and bioactive properties of its methanolic extract. in Lwt-Food Science and Technology
Elsevier Science Bv, Amsterdam., 79, 454-462.
https://doi.org/10.1016/j.lwt.2017.01.045

Stojković DS, Kovačević Grujičić N, Reis FS, Davidović S, Barros L, Popović J, Petrović I, Pavić A, Glamoclija J, Cirić A, Stevanović M, Ferreira ICFR, Soković M. Chemical composition of the mushroom Meripilus giganteus Karst. and bioactive properties of its methanolic extract. in Lwt-Food Science and Technology. 2017;79:454-462.
doi:10.1016/j.lwt.2017.01.045 .

Stojković, Dejan S., Kovačević Grujičić, Nataša, Reis, Filipa S., Davidović, Slobodan, Barros, Lillian, Popović, Jelena, Petrović, Isidora, Pavić, Aleksandar, Glamoclija, Jasmina, Cirić, Ana, Stevanović, Milena, Ferreira, Isabel C. F. R., Soković, Marina, "Chemical composition of the mushroom Meripilus giganteus Karst. and bioactive properties of its methanolic extract" in Lwt-Food Science and Technology, 79 (2017):454-462,
https://doi.org/10.1016/j.lwt.2017.01.045 . .

TY  - CONF
AU  - Tošić, Nataša
AU  - Virijević, M.
AU  - Petrović, Isidora
AU  - Kovačević Grujičić, Nataša
AU  - Davidović, Slobodan
AU  - Suvajdžić-Vuković, Nada
AU  - Pavlović, Sonja
AU  - Stevanović, Milena
PY  - 2017
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1073
PB  - Ferrata Storti Foundation, Pavia
C3  - Haematologica-The Hematology Journal
T1  - Prognostic significance of sox2, sox3, sox11, sox14 and sox18 gene expression in de novo acute myeloid leukemia (AML) patients
EP  - 390
SP  - 390
VL  - 102
UR  - https://hdl.handle.net/21.15107/rcub_imagine_1073
ER  - 

@conference{
author = "Tošić, Nataša and Virijević, M. and Petrović, Isidora and Kovačević Grujičić, Nataša and Davidović, Slobodan and Suvajdžić-Vuković, Nada and Pavlović, Sonja and Stevanović, Milena",
year = "2017",
publisher = "Ferrata Storti Foundation, Pavia",
journal = "Haematologica-The Hematology Journal",
title = "Prognostic significance of sox2, sox3, sox11, sox14 and sox18 gene expression in de novo acute myeloid leukemia (AML) patients",
pages = "390-390",
volume = "102",
url = "https://hdl.handle.net/21.15107/rcub_imagine_1073"
}

Tošić, N., Virijević, M., Petrović, I., Kovačević Grujičić, N., Davidović, S., Suvajdžić-Vuković, N., Pavlović, S.,& Stevanović, M.. (2017). Prognostic significance of sox2, sox3, sox11, sox14 and sox18 gene expression in de novo acute myeloid leukemia (AML) patients. in Haematologica-The Hematology Journal
Ferrata Storti Foundation, Pavia., 102, 390-390.
https://hdl.handle.net/21.15107/rcub_imagine_1073

Tošić N, Virijević M, Petrović I, Kovačević Grujičić N, Davidović S, Suvajdžić-Vuković N, Pavlović S, Stevanović M. Prognostic significance of sox2, sox3, sox11, sox14 and sox18 gene expression in de novo acute myeloid leukemia (AML) patients. in Haematologica-The Hematology Journal. 2017;102:390-390.
https://hdl.handle.net/21.15107/rcub_imagine_1073 .

Tošić, Nataša, Virijević, M., Petrović, Isidora, Kovačević Grujičić, Nataša, Davidović, Slobodan, Suvajdžić-Vuković, Nada, Pavlović, Sonja, Stevanović, Milena, "Prognostic significance of sox2, sox3, sox11, sox14 and sox18 gene expression in de novo acute myeloid leukemia (AML) patients" in Haematologica-The Hematology Journal, 102 (2017):390-390,
https://hdl.handle.net/21.15107/rcub_imagine_1073 .

TY  - JOUR
AU  - Davidović, Slobodan
AU  - Malyarchuk, Boris
AU  - Aleksić, Jelena M.
AU  - Derenko, Miroslava
AU  - Topalović, Vladanka
AU  - Litvinov, Andrey
AU  - Stevanović, Milena
AU  - Kovačević Grujičić, Nataša
PY  - 2015
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/894
AB  - Although south-Slavic populations have been studied to date from various aspects, the population of Serbia, occupying the central part of the Balkan Peninsula, is still genetically understudied at least at the level of mitochondrial DNA (mtDNA) variation. We analyzed polymorphisms of the first and the second mtDNA hypervariable segments (HVS-I and HVS-II) and informative coding-region markers in 139 Serbians to shed more light on their mtDNA variability, and used available data on other Slavic and neighboring non-Slavic populations to assess their interrelations in a broader European context. The contemporary Serbian mtDNA profile is consistent with the general European maternal landscape having a substantial proportion of shared haplotypes with eastern, central, and southern European populations. Serbian population was characterized as an important link between easternmost and westernmost south-Slavic populations due to the observed lack of genetic differentiation with all other south-Slavic populations and its geographical positioning within the Balkan Peninsula. An increased heterogeneity of south Slavs, most likely mirroring turbulent demographic events within the Balkan Peninsula over time (i.e., frequent admixture and differential introgression of various gene pools), and a marked geographical stratification of Slavs to south-, east-, and west-Slavic groups, were also found. A phylogeographic analyses of 20 completely sequenced Serbian mitochondrial genomes revealed not only the presence of mtDNA lineages predominantly found within the Slavic gene pool (U4a2a*, U4a2a1, U4a2c, U4a2g, HV10), supporting a common Slavic origin, but also lineages that may have originated within the southern Europe (H5*, H5e1, H5a1v) and the Balkan Peninsula in particular (H6a2b and L2a1k). Am J Phys Anthropol 156:449-465, 2015.
PB  - Wiley, Hoboken
T2  - American Journal of Physical Anthropology
T1  - Mitochondrial DNA Perspective of Serbian Genetic Diversity
EP  - 465
IS  - 3
SP  - 449
VL  - 156
DO  - 10.1002/ajpa.22670
ER  - 

@article{
author = "Davidović, Slobodan and Malyarchuk, Boris and Aleksić, Jelena M. and Derenko, Miroslava and Topalović, Vladanka and Litvinov, Andrey and Stevanović, Milena and Kovačević Grujičić, Nataša",
year = "2015",
abstract = "Although south-Slavic populations have been studied to date from various aspects, the population of Serbia, occupying the central part of the Balkan Peninsula, is still genetically understudied at least at the level of mitochondrial DNA (mtDNA) variation. We analyzed polymorphisms of the first and the second mtDNA hypervariable segments (HVS-I and HVS-II) and informative coding-region markers in 139 Serbians to shed more light on their mtDNA variability, and used available data on other Slavic and neighboring non-Slavic populations to assess their interrelations in a broader European context. The contemporary Serbian mtDNA profile is consistent with the general European maternal landscape having a substantial proportion of shared haplotypes with eastern, central, and southern European populations. Serbian population was characterized as an important link between easternmost and westernmost south-Slavic populations due to the observed lack of genetic differentiation with all other south-Slavic populations and its geographical positioning within the Balkan Peninsula. An increased heterogeneity of south Slavs, most likely mirroring turbulent demographic events within the Balkan Peninsula over time (i.e., frequent admixture and differential introgression of various gene pools), and a marked geographical stratification of Slavs to south-, east-, and west-Slavic groups, were also found. A phylogeographic analyses of 20 completely sequenced Serbian mitochondrial genomes revealed not only the presence of mtDNA lineages predominantly found within the Slavic gene pool (U4a2a*, U4a2a1, U4a2c, U4a2g, HV10), supporting a common Slavic origin, but also lineages that may have originated within the southern Europe (H5*, H5e1, H5a1v) and the Balkan Peninsula in particular (H6a2b and L2a1k). Am J Phys Anthropol 156:449-465, 2015.",
publisher = "Wiley, Hoboken",
journal = "American Journal of Physical Anthropology",
title = "Mitochondrial DNA Perspective of Serbian Genetic Diversity",
pages = "465-449",
number = "3",
volume = "156",
doi = "10.1002/ajpa.22670"
}

Davidović, S., Malyarchuk, B., Aleksić, J. M., Derenko, M., Topalović, V., Litvinov, A., Stevanović, M.,& Kovačević Grujičić, N.. (2015). Mitochondrial DNA Perspective of Serbian Genetic Diversity. in American Journal of Physical Anthropology
Wiley, Hoboken., 156(3), 449-465.
https://doi.org/10.1002/ajpa.22670

Davidović S, Malyarchuk B, Aleksić JM, Derenko M, Topalović V, Litvinov A, Stevanović M, Kovačević Grujičić N. Mitochondrial DNA Perspective of Serbian Genetic Diversity. in American Journal of Physical Anthropology. 2015;156(3):449-465.
doi:10.1002/ajpa.22670 .

Davidović, Slobodan, Malyarchuk, Boris, Aleksić, Jelena M., Derenko, Miroslava, Topalović, Vladanka, Litvinov, Andrey, Stevanović, Milena, Kovačević Grujičić, Nataša, "Mitochondrial DNA Perspective of Serbian Genetic Diversity" in American Journal of Physical Anthropology, 156, no. 3 (2015):449-465,
https://doi.org/10.1002/ajpa.22670 . .

TY  - CONF
AU  - Petrović, Isidora
AU  - Kovačević Grujičić, Nataša
AU  - Stojković, D.
AU  - Davidović, Slobodan
AU  - Glamoclija, J.
AU  - Cirić, A.
AU  - Soković, M.
AU  - Stevanović, Milena
PY  - 2014
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/729
PB  - Elsevier Sci Ltd, Oxford
C3  - European Journal of Cancer
T1  - Meripilus giganteus in prevention of cancer: Phenolic profile, biological potential and antitumor effect via upregulation of p53 and SOX1 expression in HeLa cells
EP  - S194
SP  - S194
VL  - 50
DO  - 10.1016/S0959-8049(14)50709-5
ER  - 

@conference{
author = "Petrović, Isidora and Kovačević Grujičić, Nataša and Stojković, D. and Davidović, Slobodan and Glamoclija, J. and Cirić, A. and Soković, M. and Stevanović, Milena",
year = "2014",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "European Journal of Cancer",
title = "Meripilus giganteus in prevention of cancer: Phenolic profile, biological potential and antitumor effect via upregulation of p53 and SOX1 expression in HeLa cells",
pages = "S194-S194",
volume = "50",
doi = "10.1016/S0959-8049(14)50709-5"
}

Petrović, I., Kovačević Grujičić, N., Stojković, D., Davidović, S., Glamoclija, J., Cirić, A., Soković, M.,& Stevanović, M.. (2014). Meripilus giganteus in prevention of cancer: Phenolic profile, biological potential and antitumor effect via upregulation of p53 and SOX1 expression in HeLa cells. in European Journal of Cancer
Elsevier Sci Ltd, Oxford., 50, S194-S194.
https://doi.org/10.1016/S0959-8049(14)50709-5

Petrović I, Kovačević Grujičić N, Stojković D, Davidović S, Glamoclija J, Cirić A, Soković M, Stevanović M. Meripilus giganteus in prevention of cancer: Phenolic profile, biological potential and antitumor effect via upregulation of p53 and SOX1 expression in HeLa cells. in European Journal of Cancer. 2014;50:S194-S194.
doi:10.1016/S0959-8049(14)50709-5 .

Petrović, Isidora, Kovačević Grujičić, Nataša, Stojković, D., Davidović, Slobodan, Glamoclija, J., Cirić, A., Soković, M., Stevanović, Milena, "Meripilus giganteus in prevention of cancer: Phenolic profile, biological potential and antitumor effect via upregulation of p53 and SOX1 expression in HeLa cells" in European Journal of Cancer, 50 (2014):S194-S194,
https://doi.org/10.1016/S0959-8049(14)50709-5 . .

TY  - CONF
AU  - Petrović, Isidora
AU  - Milivojević, Milena
AU  - Mojsin, Marija
AU  - Drakulić, Danijela
AU  - Kovačević Grujičić, Nataša
AU  - Topalović, Vladanka
AU  - Davidović, Slobodan
AU  - Stevanović, Milena
PY  - 2014
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/730
PB  - Elsevier Sci Ltd, Oxford
C3  - European Journal of Cancer
T1  - The role of Hedgehog signaling pathway in the regulation of SOX18 gene expression in cervical carcinoma cell line
EP  - S120
SP  - S120
VL  - 50
DO  - 10.1016/S0959-8049(14)50444-3
ER  - 

@conference{
author = "Petrović, Isidora and Milivojević, Milena and Mojsin, Marija and Drakulić, Danijela and Kovačević Grujičić, Nataša and Topalović, Vladanka and Davidović, Slobodan and Stevanović, Milena",
year = "2014",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "European Journal of Cancer",
title = "The role of Hedgehog signaling pathway in the regulation of SOX18 gene expression in cervical carcinoma cell line",
pages = "S120-S120",
volume = "50",
doi = "10.1016/S0959-8049(14)50444-3"
}

Petrović, I., Milivojević, M., Mojsin, M., Drakulić, D., Kovačević Grujičić, N., Topalović, V., Davidović, S.,& Stevanović, M.. (2014). The role of Hedgehog signaling pathway in the regulation of SOX18 gene expression in cervical carcinoma cell line. in European Journal of Cancer
Elsevier Sci Ltd, Oxford., 50, S120-S120.
https://doi.org/10.1016/S0959-8049(14)50444-3

Petrović I, Milivojević M, Mojsin M, Drakulić D, Kovačević Grujičić N, Topalović V, Davidović S, Stevanović M. The role of Hedgehog signaling pathway in the regulation of SOX18 gene expression in cervical carcinoma cell line. in European Journal of Cancer. 2014;50:S120-S120.
doi:10.1016/S0959-8049(14)50444-3 .

Petrović, Isidora, Milivojević, Milena, Mojsin, Marija, Drakulić, Danijela, Kovačević Grujičić, Nataša, Topalović, Vladanka, Davidović, Slobodan, Stevanović, Milena, "The role of Hedgehog signaling pathway in the regulation of SOX18 gene expression in cervical carcinoma cell line" in European Journal of Cancer, 50 (2014):S120-S120,
https://doi.org/10.1016/S0959-8049(14)50444-3 . .

TY  - JOUR
AU  - Stojković, Dejan S.
AU  - Davidović, Slobodan
AU  - Zivković, Jelena
AU  - Glamoclija, Jasmina
AU  - Cirić, Ana
AU  - Stevanović, Milena
AU  - Ferreira, Isabel C. F. R.
AU  - Soković, Marina
PY  - 2013
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/658
AB  - Morchella esculenta (L.) Pers. methanolic extracts, obtained from fruiting bodies growing wild in Serbia and Portugal, were screened for their antimutagenic properties and compared to protocatechuic acid, previously identified in both species. Salmonella typhimurium TA100 reversion assay was used for the antimutagenic properties. Methanolic extracts expressed important antimutagenic potency towards S. typhimurium, which was documented by index of antimutagenicity (I). A sample from Serbia expressed slightly higher antimutagenic properties with an inhibition rate of 58.7%. A sample from Portugal gave an inhibition rate of 51.7%. Protocatechuic acid had an inhibition rate I of his(+) revertants of 72.4%. Cell viability in the presence of extracts was also documented. M. esculenta samples from Serbia and Portugal possessed novel biological potential for the studied species, as well as its phenolic compound - protocatechuic acid, identified in both samples. Genotoxic effect, regarding mitotic index and chromosomal aberration score, was also assessed by using the Allium cepa L. assay. Protocatechuic acid showed the most significant decrease in mitotic index, as well as decrease in chromosomal aberration score.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Frontiers in Life Science
T1  - Comparative evaluation of antimutagenic and antimitotic effects of Morchella esculenta extracts and protocatechuic acid
EP  - 223
IS  - 3-4
SP  - 218
VL  - 7
DO  - 10.1080/21553769.2014.901925
ER  - 

@article{
author = "Stojković, Dejan S. and Davidović, Slobodan and Zivković, Jelena and Glamoclija, Jasmina and Cirić, Ana and Stevanović, Milena and Ferreira, Isabel C. F. R. and Soković, Marina",
year = "2013",
abstract = "Morchella esculenta (L.) Pers. methanolic extracts, obtained from fruiting bodies growing wild in Serbia and Portugal, were screened for their antimutagenic properties and compared to protocatechuic acid, previously identified in both species. Salmonella typhimurium TA100 reversion assay was used for the antimutagenic properties. Methanolic extracts expressed important antimutagenic potency towards S. typhimurium, which was documented by index of antimutagenicity (I). A sample from Serbia expressed slightly higher antimutagenic properties with an inhibition rate of 58.7%. A sample from Portugal gave an inhibition rate of 51.7%. Protocatechuic acid had an inhibition rate I of his(+) revertants of 72.4%. Cell viability in the presence of extracts was also documented. M. esculenta samples from Serbia and Portugal possessed novel biological potential for the studied species, as well as its phenolic compound - protocatechuic acid, identified in both samples. Genotoxic effect, regarding mitotic index and chromosomal aberration score, was also assessed by using the Allium cepa L. assay. Protocatechuic acid showed the most significant decrease in mitotic index, as well as decrease in chromosomal aberration score.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Frontiers in Life Science",
title = "Comparative evaluation of antimutagenic and antimitotic effects of Morchella esculenta extracts and protocatechuic acid",
pages = "223-218",
number = "3-4",
volume = "7",
doi = "10.1080/21553769.2014.901925"
}

Stojković, D. S., Davidović, S., Zivković, J., Glamoclija, J., Cirić, A., Stevanović, M., Ferreira, I. C. F. R.,& Soković, M.. (2013). Comparative evaluation of antimutagenic and antimitotic effects of Morchella esculenta extracts and protocatechuic acid. in Frontiers in Life Science
Taylor & Francis Ltd, Abingdon., 7(3-4), 218-223.
https://doi.org/10.1080/21553769.2014.901925

Stojković DS, Davidović S, Zivković J, Glamoclija J, Cirić A, Stevanović M, Ferreira ICFR, Soković M. Comparative evaluation of antimutagenic and antimitotic effects of Morchella esculenta extracts and protocatechuic acid. in Frontiers in Life Science. 2013;7(3-4):218-223.
doi:10.1080/21553769.2014.901925 .

Stojković, Dejan S., Davidović, Slobodan, Zivković, Jelena, Glamoclija, Jasmina, Cirić, Ana, Stevanović, Milena, Ferreira, Isabel C. F. R., Soković, Marina, "Comparative evaluation of antimutagenic and antimitotic effects of Morchella esculenta extracts and protocatechuic acid" in Frontiers in Life Science, 7, no. 3-4 (2013):218-223,
https://doi.org/10.1080/21553769.2014.901925 . .

TY  - JOUR
AU  - Popović, Visnja
AU  - Zivković, Jelena
AU  - Davidović, Slobodan
AU  - Stevanović, Milena
AU  - Stojković, Dejan
PY  - 2013
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/664
AB  - Mycotherapy is defined as the study of the use of extracts and compounds obtained from mushrooms as medicines or health-promoting agents. The present review updates the recent findings on anticancer/antitumor agents derived from mushroom extracts and their metabolites. The increasing number of studies in the past few years revealed mushroom extracts as potent antitumor agents. Also, numerous studies were conducted on bioactive compounds isolated from mushrooms reporting the heteropolysaccharides, beta-glucans, alpha-glucans, proteins, complexes of polysaccharides with proteins, fatty acids, nucleoside antagonists, terpenoids, sesquiterpenes, lanostanoids, sterols and phenolic acids as promising antitumor agents. Also, molecular mechanisms of cytotoxicity against different cancer cell lines are discussed in this review. Findings with Antrodia camphorata and Ganoderma lucidium extracts and isolated compounds are presented, as being the most deeply studied previously.
PB  - Bentham Science Publ Ltd, Sharjah
T2  - Current Topics in Medicinal Chemistry
T1  - Mycotherapy of Cancer: An Update on Cytotoxic and Antitumor Activities of Mushrooms, Bioactive Principles and Molecular Mechanisms of their Action
EP  - 2806
IS  - 21
SP  - 2791
VL  - 13
DO  - 10.2174/15680266113136660198
ER  - 

@article{
author = "Popović, Visnja and Zivković, Jelena and Davidović, Slobodan and Stevanović, Milena and Stojković, Dejan",
year = "2013",
abstract = "Mycotherapy is defined as the study of the use of extracts and compounds obtained from mushrooms as medicines or health-promoting agents. The present review updates the recent findings on anticancer/antitumor agents derived from mushroom extracts and their metabolites. The increasing number of studies in the past few years revealed mushroom extracts as potent antitumor agents. Also, numerous studies were conducted on bioactive compounds isolated from mushrooms reporting the heteropolysaccharides, beta-glucans, alpha-glucans, proteins, complexes of polysaccharides with proteins, fatty acids, nucleoside antagonists, terpenoids, sesquiterpenes, lanostanoids, sterols and phenolic acids as promising antitumor agents. Also, molecular mechanisms of cytotoxicity against different cancer cell lines are discussed in this review. Findings with Antrodia camphorata and Ganoderma lucidium extracts and isolated compounds are presented, as being the most deeply studied previously.",
publisher = "Bentham Science Publ Ltd, Sharjah",
journal = "Current Topics in Medicinal Chemistry",
title = "Mycotherapy of Cancer: An Update on Cytotoxic and Antitumor Activities of Mushrooms, Bioactive Principles and Molecular Mechanisms of their Action",
pages = "2806-2791",
number = "21",
volume = "13",
doi = "10.2174/15680266113136660198"
}

Popović, V., Zivković, J., Davidović, S., Stevanović, M.,& Stojković, D.. (2013). Mycotherapy of Cancer: An Update on Cytotoxic and Antitumor Activities of Mushrooms, Bioactive Principles and Molecular Mechanisms of their Action. in Current Topics in Medicinal Chemistry
Bentham Science Publ Ltd, Sharjah., 13(21), 2791-2806.
https://doi.org/10.2174/15680266113136660198

Popović V, Zivković J, Davidović S, Stevanović M, Stojković D. Mycotherapy of Cancer: An Update on Cytotoxic and Antitumor Activities of Mushrooms, Bioactive Principles and Molecular Mechanisms of their Action. in Current Topics in Medicinal Chemistry. 2013;13(21):2791-2806.
doi:10.2174/15680266113136660198 .

Popović, Visnja, Zivković, Jelena, Davidović, Slobodan, Stevanović, Milena, Stojković, Dejan, "Mycotherapy of Cancer: An Update on Cytotoxic and Antitumor Activities of Mushrooms, Bioactive Principles and Molecular Mechanisms of their Action" in Current Topics in Medicinal Chemistry, 13, no. 21 (2013):2791-2806,
https://doi.org/10.2174/15680266113136660198 . .

TY  - JOUR
AU  - Kovačević Grujičić, Nataša
AU  - Davidović, Slobodan
AU  - Takić, Dijana
AU  - Mojsin, Marija
AU  - Stevanović, Milena
PY  - 2012
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/578
AB  - Amplification of human mitochondrial DNA (mtDNA) has been widely used in population genetics, human evolutionary and molecular anthropology studies. mtDNA hypervariable segments I and II (HVSI and HVSII) were shown to be a suitable tool in genetic analyses due to the unique properties of mtDNA, such as the lack of recombination, maternal mode of inheritance, rapid evolutionary rate and high population-specific polymorphisms. Here we present a rapid and low-cost method for direct PCR amplification of a 330 bp fragment of HVSI from buccal cell samples. Avoiding the DNA isolation step makes this method appropriate for the analysis of a large number of samples in a short period of time. Since the transportation of samples and fieldwork conditions can affect the quality of samples and subsequent DNA analysis, we tested the effects of long-term storage of buccal cell swabs on the suitability of such samples for direct PCR amplification. We efficiently amplified a 330 bp fragment of HVSI even after the long-term storage of buccal cells at room temperature, +4°C or at -20°C, for up to eight months. All examined PCR products were successfully sequenced, regardless of sample storage time and conditions. Our results suggest that the direct PCR amplification of the HVSI region from buccal cells is a method well suited for large-scale mtDNA population studies.
PB  - Srpsko biološko društvo, Beograd, i dr.
T2  - Archives of Biological Sciences
T1  - Direct PCR amplification of the HVSI region in mitochondrial DNA from buccal cell swabs
EP  - 858
IS  - 3
SP  - 851
VL  - 64
DO  - 10.2298/ABS1203851G
ER  - 

@article{
author = "Kovačević Grujičić, Nataša and Davidović, Slobodan and Takić, Dijana and Mojsin, Marija and Stevanović, Milena",
year = "2012",
abstract = "Amplification of human mitochondrial DNA (mtDNA) has been widely used in population genetics, human evolutionary and molecular anthropology studies. mtDNA hypervariable segments I and II (HVSI and HVSII) were shown to be a suitable tool in genetic analyses due to the unique properties of mtDNA, such as the lack of recombination, maternal mode of inheritance, rapid evolutionary rate and high population-specific polymorphisms. Here we present a rapid and low-cost method for direct PCR amplification of a 330 bp fragment of HVSI from buccal cell samples. Avoiding the DNA isolation step makes this method appropriate for the analysis of a large number of samples in a short period of time. Since the transportation of samples and fieldwork conditions can affect the quality of samples and subsequent DNA analysis, we tested the effects of long-term storage of buccal cell swabs on the suitability of such samples for direct PCR amplification. We efficiently amplified a 330 bp fragment of HVSI even after the long-term storage of buccal cells at room temperature, +4°C or at -20°C, for up to eight months. All examined PCR products were successfully sequenced, regardless of sample storage time and conditions. Our results suggest that the direct PCR amplification of the HVSI region from buccal cells is a method well suited for large-scale mtDNA population studies.",
publisher = "Srpsko biološko društvo, Beograd, i dr.",
journal = "Archives of Biological Sciences",
title = "Direct PCR amplification of the HVSI region in mitochondrial DNA from buccal cell swabs",
pages = "858-851",
number = "3",
volume = "64",
doi = "10.2298/ABS1203851G"
}

Kovačević Grujičić, N., Davidović, S., Takić, D., Mojsin, M.,& Stevanović, M.. (2012). Direct PCR amplification of the HVSI region in mitochondrial DNA from buccal cell swabs. in Archives of Biological Sciences
Srpsko biološko društvo, Beograd, i dr.., 64(3), 851-858.
https://doi.org/10.2298/ABS1203851G

Kovačević Grujičić N, Davidović S, Takić D, Mojsin M, Stevanović M. Direct PCR amplification of the HVSI region in mitochondrial DNA from buccal cell swabs. in Archives of Biological Sciences. 2012;64(3):851-858.
doi:10.2298/ABS1203851G .

Kovačević Grujičić, Nataša, Davidović, Slobodan, Takić, Dijana, Mojsin, Marija, Stevanović, Milena, "Direct PCR amplification of the HVSI region in mitochondrial DNA from buccal cell swabs" in Archives of Biological Sciences, 64, no. 3 (2012):851-858,
https://doi.org/10.2298/ABS1203851G . .