TY  - JOUR
AU  - Zavisić, Gordana
AU  - Petricević, Sasa
AU  - Radulović, Zeljka
AU  - Begović, Jelena
AU  - Golić, Nataša
AU  - Topisirović, Ljubiša
AU  - Strahinić, Ivana
PY  - 2012
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/571
AB  - In this study, we checked lactobacilli strains of human origin for their potential as probiotic. Samples were collected from oral mucosa of 16 healthy individuals, out of which twenty isolates were obtained and two of them were selected and identified as Lactobacillus plantarum (G1) and L. casei (G3). Both isolates exhibited antagonistic action towards pathogenic microorganisms such as Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Salmonella abony, and Clostridium sporogenes, but not on the growth of Candida albicans. The bacteriocin activity against Staphylococcus aureus ATCC 6358-P was shown only by L. plantarum G1. Moreover, the isolates G1 and G3 showed good viability in the acid gastric environment and in the gut environment containing bovine bile salts. The viability of G1 and G3 isolates in the gastrointestinal tract, and the adhesion to the intestinal mucosa were also confirmed in vivo. The biochemical tests of blood samples revealed lower levels of serum triglycerides and cholesterol, as well as reduced activity of alkaline phosphatase in all lactobacilli-treated Wistar rats, compared to control ones. No toxicity for NMRI Ham mice was observed. According to our experimental results, these findings imply that L. plantarum G1 and L. casei G3 could be characterized as potential probiotics.
PB  - Sociedade Brasileira de Microbiologia
T2  - Brazilian Journal of Microbiology
T1  - Probiotic features of two oral lactobacillus isolates
EP  - 428
IS  - 1
SP  - 418
VL  - 43
DO  - 10.1590/S1517-83822012000100050
ER  - 

@article{
author = "Zavisić, Gordana and Petricević, Sasa and Radulović, Zeljka and Begović, Jelena and Golić, Nataša and Topisirović, Ljubiša and Strahinić, Ivana",
year = "2012",
abstract = "In this study, we checked lactobacilli strains of human origin for their potential as probiotic. Samples were collected from oral mucosa of 16 healthy individuals, out of which twenty isolates were obtained and two of them were selected and identified as Lactobacillus plantarum (G1) and L. casei (G3). Both isolates exhibited antagonistic action towards pathogenic microorganisms such as Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Salmonella abony, and Clostridium sporogenes, but not on the growth of Candida albicans. The bacteriocin activity against Staphylococcus aureus ATCC 6358-P was shown only by L. plantarum G1. Moreover, the isolates G1 and G3 showed good viability in the acid gastric environment and in the gut environment containing bovine bile salts. The viability of G1 and G3 isolates in the gastrointestinal tract, and the adhesion to the intestinal mucosa were also confirmed in vivo. The biochemical tests of blood samples revealed lower levels of serum triglycerides and cholesterol, as well as reduced activity of alkaline phosphatase in all lactobacilli-treated Wistar rats, compared to control ones. No toxicity for NMRI Ham mice was observed. According to our experimental results, these findings imply that L. plantarum G1 and L. casei G3 could be characterized as potential probiotics.",
publisher = "Sociedade Brasileira de Microbiologia",
journal = "Brazilian Journal of Microbiology",
title = "Probiotic features of two oral lactobacillus isolates",
pages = "428-418",
number = "1",
volume = "43",
doi = "10.1590/S1517-83822012000100050"
}

Zavisić, G., Petricević, S., Radulović, Z., Begović, J., Golić, N., Topisirović, L.,& Strahinić, I.. (2012). Probiotic features of two oral lactobacillus isolates. in Brazilian Journal of Microbiology
Sociedade Brasileira de Microbiologia., 43(1), 418-428.
https://doi.org/10.1590/S1517-83822012000100050

Zavisić G, Petricević S, Radulović Z, Begović J, Golić N, Topisirović L, Strahinić I. Probiotic features of two oral lactobacillus isolates. in Brazilian Journal of Microbiology. 2012;43(1):418-428.
doi:10.1590/S1517-83822012000100050 .

Zavisić, Gordana, Petricević, Sasa, Radulović, Zeljka, Begović, Jelena, Golić, Nataša, Topisirović, Ljubiša, Strahinić, Ivana, "Probiotic features of two oral lactobacillus isolates" in Brazilian Journal of Microbiology, 43, no. 1 (2012):418-428,
https://doi.org/10.1590/S1517-83822012000100050 . .