Plants and synthetic bioactive products of new generation

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Plants and synthetic bioactive products of new generation (en)
Биљни и синтетички биоактивни производи новије генерације (sr)
Biljni i sintetički bioaktivni proizvodi novije generacije (sr_RS)
Authors

Publications

Antimicrobial and Cytotoxic Activities of the Sulphur Shelf Medicinal Mushroom, Laetiporus sulphureus (Agaricomycetes), from Serbia

Kolundzić, Marina D.; Grozdanić, Nada D.; Stanojković, Tatjana P.; Milenković, Marina T.; Dinić, Miroslav; Golić, Nataša; Kojić, Milan; Kundaković, Tatjana D.

(Begell House Inc, Danbury, 2016)

TY  - JOUR
AU  - Kolundzić, Marina D.
AU  - Grozdanić, Nada D.
AU  - Stanojković, Tatjana P.
AU  - Milenković, Marina T.
AU  - Dinić, Miroslav
AU  - Golić, Nataša
AU  - Kojić, Milan
AU  - Kundaković, Tatjana D.
PY  - 2016
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/921
AB  - Cyclohexane, dichloromethane, and methanol extracts of the medicinal mushroom Laetiporus sulphureus were tested for their antimicrobial, cytotoxic, and radical scavenging activities. Total polyphenol content was also determined. Regarding the amount of the phenolic compounds in the methanol extract, there were 14.1 +/- 0.6 mg gallic acid/g dry extract and a concentration of 0.66 +/- 0.15 mg/mL resulted in the removal of 50% of the DPPH radicals (half-maximal inhibitory concentration [IC50]) . The average minimum inhibitory concentrations (MICs) against a select panel of microorganisms were between 125 and 250 mu g/mL, and the methanolic extract significantly inhibited the growth of Staphylococcus aureus (MIC, 31.25 mu g/mL). Also, cyclohexane and dichloromethane extracts inhibited the growth of Helicobacter pylori (MIC, 62.5 mu g/mL). Cyclohexane and dichloromethane extracts showed higher antiproliferative action compared with the methanol extract. The lowest IC50 was induced on HeLa cells by dichloromethane extract (IC50,67.20 +/- 5.49 mu g/mL), followed by cyclohexane extract (IC50 75.91 +/- 1.57 mu g/mL). The tested cyclohexane and dichloromethane extracts possessed moderate antibacterial and significant cytotoxic activity against both malignant (HeLa and N87) and healthy (MRC5) cell lines. Methanol extracts exhibited promising anti-Helicobacter activity without cytotoxicity against N87 and MRC5 cell lines.
PB  - Begell House Inc, Danbury
T2  - International Journal of Medicinal Mushrooms
T1  - Antimicrobial and Cytotoxic Activities of the Sulphur Shelf Medicinal Mushroom, Laetiporus sulphureus (Agaricomycetes), from Serbia
EP  - 476
IS  - 6
SP  - 469
VL  - 18
DO  - 10.1615/IntJMedMushrooms.v18.i6.10
ER  - 
@article{
author = "Kolundzić, Marina D. and Grozdanić, Nada D. and Stanojković, Tatjana P. and Milenković, Marina T. and Dinić, Miroslav and Golić, Nataša and Kojić, Milan and Kundaković, Tatjana D.",
year = "2016",
abstract = "Cyclohexane, dichloromethane, and methanol extracts of the medicinal mushroom Laetiporus sulphureus were tested for their antimicrobial, cytotoxic, and radical scavenging activities. Total polyphenol content was also determined. Regarding the amount of the phenolic compounds in the methanol extract, there were 14.1 +/- 0.6 mg gallic acid/g dry extract and a concentration of 0.66 +/- 0.15 mg/mL resulted in the removal of 50% of the DPPH radicals (half-maximal inhibitory concentration [IC50]) . The average minimum inhibitory concentrations (MICs) against a select panel of microorganisms were between 125 and 250 mu g/mL, and the methanolic extract significantly inhibited the growth of Staphylococcus aureus (MIC, 31.25 mu g/mL). Also, cyclohexane and dichloromethane extracts inhibited the growth of Helicobacter pylori (MIC, 62.5 mu g/mL). Cyclohexane and dichloromethane extracts showed higher antiproliferative action compared with the methanol extract. The lowest IC50 was induced on HeLa cells by dichloromethane extract (IC50,67.20 +/- 5.49 mu g/mL), followed by cyclohexane extract (IC50 75.91 +/- 1.57 mu g/mL). The tested cyclohexane and dichloromethane extracts possessed moderate antibacterial and significant cytotoxic activity against both malignant (HeLa and N87) and healthy (MRC5) cell lines. Methanol extracts exhibited promising anti-Helicobacter activity without cytotoxicity against N87 and MRC5 cell lines.",
publisher = "Begell House Inc, Danbury",
journal = "International Journal of Medicinal Mushrooms",
title = "Antimicrobial and Cytotoxic Activities of the Sulphur Shelf Medicinal Mushroom, Laetiporus sulphureus (Agaricomycetes), from Serbia",
pages = "476-469",
number = "6",
volume = "18",
doi = "10.1615/IntJMedMushrooms.v18.i6.10"
}
Kolundzić, M. D., Grozdanić, N. D., Stanojković, T. P., Milenković, M. T., Dinić, M., Golić, N., Kojić, M.,& Kundaković, T. D.. (2016). Antimicrobial and Cytotoxic Activities of the Sulphur Shelf Medicinal Mushroom, Laetiporus sulphureus (Agaricomycetes), from Serbia. in International Journal of Medicinal Mushrooms
Begell House Inc, Danbury., 18(6), 469-476.
https://doi.org/10.1615/IntJMedMushrooms.v18.i6.10
Kolundzić MD, Grozdanić ND, Stanojković TP, Milenković MT, Dinić M, Golić N, Kojić M, Kundaković TD. Antimicrobial and Cytotoxic Activities of the Sulphur Shelf Medicinal Mushroom, Laetiporus sulphureus (Agaricomycetes), from Serbia. in International Journal of Medicinal Mushrooms. 2016;18(6):469-476.
doi:10.1615/IntJMedMushrooms.v18.i6.10 .
Kolundzić, Marina D., Grozdanić, Nada D., Stanojković, Tatjana P., Milenković, Marina T., Dinić, Miroslav, Golić, Nataša, Kojić, Milan, Kundaković, Tatjana D., "Antimicrobial and Cytotoxic Activities of the Sulphur Shelf Medicinal Mushroom, Laetiporus sulphureus (Agaricomycetes), from Serbia" in International Journal of Medicinal Mushrooms, 18, no. 6 (2016):469-476,
https://doi.org/10.1615/IntJMedMushrooms.v18.i6.10 . .
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Anti-Helicobacter pylori Activity of Four Alchemilla Species (Rosaceae)

Krivokuca, Marija; Niketić, Marjan; Milenković, Marina; Golić, Nataša; Masia, Carla; Scaltrito, Maria Maddalena; Sisto, Francesca; Kundaković, Tatjana

(Natural Product Incorporation, 2015)

TY  - JOUR
AU  - Krivokuca, Marija
AU  - Niketić, Marjan
AU  - Milenković, Marina
AU  - Golić, Nataša
AU  - Masia, Carla
AU  - Scaltrito, Maria Maddalena
AU  - Sisto, Francesca
AU  - Kundaković, Tatjana
PY  - 2015
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/863
AB  - The present study evaluated the anti-Helicobacter pylori activity of Alchemilla glabra Neygenf. (A. sect. Alchemilla), A. monticola Opiz (A. sect. Plicatae S.E. Frohner), A. fissa Gunther & Schummel (A. sect. Calycinae (Buser) Buser) and A. viridiflora Rothm. (A. sect. Calycinae), and identified ellagic acid and quercetin-3-O-beta-D-glucoside. Anti-H. pylori activity was tested against ten clinical isolates and one reference strain (ATCC 43504). The methanol extracts were more active than the dichloromethane and cyclohexane extracts. The ranges of concentrations were between 4 mu g/mL for methanol extracts of A. viridiflora, A. glabra and A. monticola, and 256 mu g/mL for cyclohexane extracts of A. viridiflora, A. glabra and A. fissa. The best overall activity was obtained with A. monticola extracts. No significant difference was found in the ellagic acid contents of the methanol extracts of the tested Alchemilla species (0.2-0.3 mg/mL), and anti-H. pylori activity was similar (4-32 mu g/mL). Ellagic acid exhibited strong activity at very low concentrations (0.125-0.5 mu g/mL), while the second identified compound, quercetin-3-O-beta-D-glucoside, was also very active in concentration of 2-16 mu g/mL.
PB  - Natural Product Incorporation
T2  - Natural Product Communications
T1  - Anti-Helicobacter pylori Activity of Four Alchemilla Species (Rosaceae)
EP  - 1371
IS  - 8
SP  - 1369
VL  - 10
DO  - 10.1177/1934578x1501000814
ER  - 
@article{
author = "Krivokuca, Marija and Niketić, Marjan and Milenković, Marina and Golić, Nataša and Masia, Carla and Scaltrito, Maria Maddalena and Sisto, Francesca and Kundaković, Tatjana",
year = "2015",
abstract = "The present study evaluated the anti-Helicobacter pylori activity of Alchemilla glabra Neygenf. (A. sect. Alchemilla), A. monticola Opiz (A. sect. Plicatae S.E. Frohner), A. fissa Gunther & Schummel (A. sect. Calycinae (Buser) Buser) and A. viridiflora Rothm. (A. sect. Calycinae), and identified ellagic acid and quercetin-3-O-beta-D-glucoside. Anti-H. pylori activity was tested against ten clinical isolates and one reference strain (ATCC 43504). The methanol extracts were more active than the dichloromethane and cyclohexane extracts. The ranges of concentrations were between 4 mu g/mL for methanol extracts of A. viridiflora, A. glabra and A. monticola, and 256 mu g/mL for cyclohexane extracts of A. viridiflora, A. glabra and A. fissa. The best overall activity was obtained with A. monticola extracts. No significant difference was found in the ellagic acid contents of the methanol extracts of the tested Alchemilla species (0.2-0.3 mg/mL), and anti-H. pylori activity was similar (4-32 mu g/mL). Ellagic acid exhibited strong activity at very low concentrations (0.125-0.5 mu g/mL), while the second identified compound, quercetin-3-O-beta-D-glucoside, was also very active in concentration of 2-16 mu g/mL.",
publisher = "Natural Product Incorporation",
journal = "Natural Product Communications",
title = "Anti-Helicobacter pylori Activity of Four Alchemilla Species (Rosaceae)",
pages = "1371-1369",
number = "8",
volume = "10",
doi = "10.1177/1934578x1501000814"
}
Krivokuca, M., Niketić, M., Milenković, M., Golić, N., Masia, C., Scaltrito, M. M., Sisto, F.,& Kundaković, T.. (2015). Anti-Helicobacter pylori Activity of Four Alchemilla Species (Rosaceae). in Natural Product Communications
Natural Product Incorporation., 10(8), 1369-1371.
https://doi.org/10.1177/1934578x1501000814
Krivokuca M, Niketić M, Milenković M, Golić N, Masia C, Scaltrito MM, Sisto F, Kundaković T. Anti-Helicobacter pylori Activity of Four Alchemilla Species (Rosaceae). in Natural Product Communications. 2015;10(8):1369-1371.
doi:10.1177/1934578x1501000814 .
Krivokuca, Marija, Niketić, Marjan, Milenković, Marina, Golić, Nataša, Masia, Carla, Scaltrito, Maria Maddalena, Sisto, Francesca, Kundaković, Tatjana, "Anti-Helicobacter pylori Activity of Four Alchemilla Species (Rosaceae)" in Natural Product Communications, 10, no. 8 (2015):1369-1371,
https://doi.org/10.1177/1934578x1501000814 . .
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Antimikrobna aktivnost ekstrakata origana (Origanum vulgare L.) i bosiljka (Ocimum basilicum L.)

Brđanin, Stanislava; Bogdanović, Nemanja; Kolundžić, Marina; Milenković, Marina; Golić, Nataša; Kojić, Milan; Kundaković, Tatjana

(Univerzitet u Nišu - Tehnološki fakultet, Leskovac, 2015)

TY  - JOUR
AU  - Brđanin, Stanislava
AU  - Bogdanović, Nemanja
AU  - Kolundžić, Marina
AU  - Milenković, Marina
AU  - Golić, Nataša
AU  - Kojić, Milan
AU  - Kundaković, Tatjana
PY  - 2015
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/858
AB  - Komercijalni uzorci nadzemnih delova Origanum vulgare L. i Ocimum basilicum L. (Lamiaceae) su korišćeni za određivanje antimikrobne aktivnosti. Aktivnost ekstrakata različite polarnosti je testirana protiv izabranih mikroorganizama, uključujući laboratorijski soj Helicobacter pilori NCTC 12868. Testirani ekstrakti su imali umerenu aktivnost. Ekstrakti O. vulgare su bili aktivniji protiv bakterija, posebno Gram pozitivnih bakterija sa minimalnim inhibitornim koncentracijama (MIK) između 62,5 i 125 μg/mL, od ekstrakata O. basilicum koji su pokazali aktivnost protiv Candida albicans (MIK 125 μg/mL). Cikloheksanski ekstrakt O. vulgare nije pokazao antimikrobnu aktivnost na testirani H. pylori, dok su ostali testirani ekstrakti bili aktivni sa MIK vrednostima između 250 μg/mL i 500 μg/mL. Identifikovana i kvantifikovana ruzmarinska kiselina i druga polarna jedinjenja mogu predstavljati aktivna jedinjenja sa antibakterijskom aktivnošću u ovim začinima.
AB  - The commercial samples of aerial parts of Origanum vulgare L. and Ocimum basilicum L. (Lamiaceae) were tested for antimicrobial activity. The activity of the extracts with different polarity was tested against a panel of microorganisms, including laboratory strain Helicobacter pylori NCTC 12868. The tested extracts showed a moderate activity. The extracts of O. vulgare were more active against bacteria, especially against Gram positive bacteria with the minimal inhibitory concentration (MIC) between 62.5 and 125 μg/mL, than the extracts of O. basilicum which were active against Candida albicans (MIC 125 μg/mL). Cyclohexane extract of O. vulgare did not show any activity against tested H. pylori, while all other tested extracts were active with MICs between 250 μg/mL and 500 μg/mL. Identified and quantified rosmarinic acid and other polar compounds could be active antibacterial compounds in these spices.
PB  - Univerzitet u Nišu - Tehnološki fakultet, Leskovac
T2  - Advanced Technologies
T1  - Antimikrobna aktivnost ekstrakata origana (Origanum vulgare L.) i bosiljka (Ocimum basilicum L.)
T1  - Antimicrobial activity of oregano (Origanum vulgare L.): And basil (Ocimum basilicum L.): Extracts
EP  - 10
IS  - 2
SP  - 5
VL  - 4
DO  - 10.5937/savteh1502005B
ER  - 
@article{
author = "Brđanin, Stanislava and Bogdanović, Nemanja and Kolundžić, Marina and Milenković, Marina and Golić, Nataša and Kojić, Milan and Kundaković, Tatjana",
year = "2015",
abstract = "Komercijalni uzorci nadzemnih delova Origanum vulgare L. i Ocimum basilicum L. (Lamiaceae) su korišćeni za određivanje antimikrobne aktivnosti. Aktivnost ekstrakata različite polarnosti je testirana protiv izabranih mikroorganizama, uključujući laboratorijski soj Helicobacter pilori NCTC 12868. Testirani ekstrakti su imali umerenu aktivnost. Ekstrakti O. vulgare su bili aktivniji protiv bakterija, posebno Gram pozitivnih bakterija sa minimalnim inhibitornim koncentracijama (MIK) između 62,5 i 125 μg/mL, od ekstrakata O. basilicum koji su pokazali aktivnost protiv Candida albicans (MIK 125 μg/mL). Cikloheksanski ekstrakt O. vulgare nije pokazao antimikrobnu aktivnost na testirani H. pylori, dok su ostali testirani ekstrakti bili aktivni sa MIK vrednostima između 250 μg/mL i 500 μg/mL. Identifikovana i kvantifikovana ruzmarinska kiselina i druga polarna jedinjenja mogu predstavljati aktivna jedinjenja sa antibakterijskom aktivnošću u ovim začinima., The commercial samples of aerial parts of Origanum vulgare L. and Ocimum basilicum L. (Lamiaceae) were tested for antimicrobial activity. The activity of the extracts with different polarity was tested against a panel of microorganisms, including laboratory strain Helicobacter pylori NCTC 12868. The tested extracts showed a moderate activity. The extracts of O. vulgare were more active against bacteria, especially against Gram positive bacteria with the minimal inhibitory concentration (MIC) between 62.5 and 125 μg/mL, than the extracts of O. basilicum which were active against Candida albicans (MIC 125 μg/mL). Cyclohexane extract of O. vulgare did not show any activity against tested H. pylori, while all other tested extracts were active with MICs between 250 μg/mL and 500 μg/mL. Identified and quantified rosmarinic acid and other polar compounds could be active antibacterial compounds in these spices.",
publisher = "Univerzitet u Nišu - Tehnološki fakultet, Leskovac",
journal = "Advanced Technologies",
title = "Antimikrobna aktivnost ekstrakata origana (Origanum vulgare L.) i bosiljka (Ocimum basilicum L.), Antimicrobial activity of oregano (Origanum vulgare L.): And basil (Ocimum basilicum L.): Extracts",
pages = "10-5",
number = "2",
volume = "4",
doi = "10.5937/savteh1502005B"
}
Brđanin, S., Bogdanović, N., Kolundžić, M., Milenković, M., Golić, N., Kojić, M.,& Kundaković, T.. (2015). Antimikrobna aktivnost ekstrakata origana (Origanum vulgare L.) i bosiljka (Ocimum basilicum L.). in Advanced Technologies
Univerzitet u Nišu - Tehnološki fakultet, Leskovac., 4(2), 5-10.
https://doi.org/10.5937/savteh1502005B
Brđanin S, Bogdanović N, Kolundžić M, Milenković M, Golić N, Kojić M, Kundaković T. Antimikrobna aktivnost ekstrakata origana (Origanum vulgare L.) i bosiljka (Ocimum basilicum L.). in Advanced Technologies. 2015;4(2):5-10.
doi:10.5937/savteh1502005B .
Brđanin, Stanislava, Bogdanović, Nemanja, Kolundžić, Marina, Milenković, Marina, Golić, Nataša, Kojić, Milan, Kundaković, Tatjana, "Antimikrobna aktivnost ekstrakata origana (Origanum vulgare L.) i bosiljka (Ocimum basilicum L.)" in Advanced Technologies, 4, no. 2 (2015):5-10,
https://doi.org/10.5937/savteh1502005B . .
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