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Cytotoxicity of the gold complex based on mercaptotriazole - A comparison with the conventional cyanide electrolyte

Dimitrijević, Silvana B.; Alagić, Sladana; Pavlović, Sonja; Stanković, Biljana; Kotur, Nikola; Ivanović, Aleksandra; Dimitrijević, Stevan P.

(Elsevier, Amsterdam, 2021)

TY  - JOUR
AU  - Dimitrijević, Silvana B.
AU  - Alagić, Sladana
AU  - Pavlović, Sonja
AU  - Stanković, Biljana
AU  - Kotur, Nikola
AU  - Ivanović, Aleksandra
AU  - Dimitrijević, Stevan P.
PY  - 2021
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1480
AB  - The study presents the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay results on human erythroleukemia K562 cell line to compare the toxicity of electrolytes based on the mercaptotriazole gold complex (Au-MT) and gold potassium cyanide. Solutions immediately after mixing and after three months at different concentrations were compared, with a prolonged aging period, to a year, for the electrolytes at pH = 9. Lower toxicity of new organic gold complex at pH = 4, 7, and 12 than of alkaline cyanide electrolyte, but higher at pH = 2, was determined. The solution of the Au-MT at pH = 9 had comparable, but lower cell toxicity in the whole investigated period.
PB  - Elsevier, Amsterdam
T2  - Journal of the Indian Chemical Society
T1  - Cytotoxicity of the gold complex based on mercaptotriazole - A comparison with the conventional cyanide electrolyte
IS  - 11
VL  - 98
DO  - 10.1016/j.jics.2021.100219
ER  - 
@article{
author = "Dimitrijević, Silvana B. and Alagić, Sladana and Pavlović, Sonja and Stanković, Biljana and Kotur, Nikola and Ivanović, Aleksandra and Dimitrijević, Stevan P.",
year = "2021",
abstract = "The study presents the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay results on human erythroleukemia K562 cell line to compare the toxicity of electrolytes based on the mercaptotriazole gold complex (Au-MT) and gold potassium cyanide. Solutions immediately after mixing and after three months at different concentrations were compared, with a prolonged aging period, to a year, for the electrolytes at pH = 9. Lower toxicity of new organic gold complex at pH = 4, 7, and 12 than of alkaline cyanide electrolyte, but higher at pH = 2, was determined. The solution of the Au-MT at pH = 9 had comparable, but lower cell toxicity in the whole investigated period.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of the Indian Chemical Society",
title = "Cytotoxicity of the gold complex based on mercaptotriazole - A comparison with the conventional cyanide electrolyte",
number = "11",
volume = "98",
doi = "10.1016/j.jics.2021.100219"
}
Dimitrijević, S. B., Alagić, S., Pavlović, S., Stanković, B., Kotur, N., Ivanović, A.,& Dimitrijević, S. P.. (2021). Cytotoxicity of the gold complex based on mercaptotriazole - A comparison with the conventional cyanide electrolyte. in Journal of the Indian Chemical Society
Elsevier, Amsterdam., 98(11).
https://doi.org/10.1016/j.jics.2021.100219
Dimitrijević SB, Alagić S, Pavlović S, Stanković B, Kotur N, Ivanović A, Dimitrijević SP. Cytotoxicity of the gold complex based on mercaptotriazole - A comparison with the conventional cyanide electrolyte. in Journal of the Indian Chemical Society. 2021;98(11).
doi:10.1016/j.jics.2021.100219 .
Dimitrijević, Silvana B., Alagić, Sladana, Pavlović, Sonja, Stanković, Biljana, Kotur, Nikola, Ivanović, Aleksandra, Dimitrijević, Stevan P., "Cytotoxicity of the gold complex based on mercaptotriazole - A comparison with the conventional cyanide electrolyte" in Journal of the Indian Chemical Society, 98, no. 11 (2021),
https://doi.org/10.1016/j.jics.2021.100219 . .
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