TY  - JOUR
AU  - Ašanin, Darko
AU  - Andrejević, Tina
AU  - Nenadović, Marija
AU  - Rodić, Marko
AU  - Vojnović, Sandra
AU  - Djuran, Miloš
AU  - Glišić, Biljana
PY  - 2023
UR  - https://www.sciencedirect.com/science/article/pii/S0277538723003078
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/2067
AB  - In the present study, synthesis of silver(I) and gold(III) coordination compounds with 1,6-naphthyridine (1,6-naph), {[Ag(1,6-naph)(H2O)](BF4)}n (1) and [AuCl3(1,6-naph)] (2), was reported. The methods used for the structural characterization of a new compound 1 included IR, NMR (1H and 13C) and UV-Vis spectroscopy, cyclic voltammetry and single-crystal X-ray diffraction analysis. The crystallographic results showed that compound 1 represents silver(I) coordination polymer, in which 1,6-naph ligand acts as a bidentate bridging ligand connecting two Ag(I) ions via its N1 and N6 nitrogen atoms, while the third coordination site of the metal ion is occupied by the water oxygen atom, resulted in a T-shape geometry. Compounds 1 and 2 were evaluated in vitro for antimicrobial activity against five bacterial and two Candida species, while their cytotoxicity was tested on the normal human lung fibroblast cell line (MRC-5). Compound 1 has manifested a remarkable antifungal activity on both tested Candida strains (C. albicans and C. parapsilosis) with minimal inhibitory concentrations (MICs) of 1.43 and 11.38 µM (0.49 and 3.9 µg/mL), respectively, while no significant antimicrobial activity was observed for 2. Moreover, silver(I) coordination polymer 1 inhibits the hyphae formation of C. albicans at subinhibitory concentration. The binding affinity of both compounds 1 and 2 with calf thymus DNA (ct-DNA) and bovine serum albumin (BSA) was studied by fluorescence spectroscopy, indicating their ability to interact with these biomolecules, with compound 2 being more reactive.
T2  - Polyhedron
T1  - Comparative study of antimicrobial potential and DNA/BSA binding affinity of silver(I) and gold(III) coordination compounds with 1,6-naphthyridine
IS  - 1
SP  - 116585
VL  - 244
DO  - 10.1016/j.poly.2023.116585
ER  - 

@article{
author = "Ašanin, Darko and Andrejević, Tina and Nenadović, Marija and Rodić, Marko and Vojnović, Sandra and Djuran, Miloš and Glišić, Biljana",
year = "2023",
abstract = "In the present study, synthesis of silver(I) and gold(III) coordination compounds with 1,6-naphthyridine (1,6-naph), {[Ag(1,6-naph)(H2O)](BF4)}n (1) and [AuCl3(1,6-naph)] (2), was reported. The methods used for the structural characterization of a new compound 1 included IR, NMR (1H and 13C) and UV-Vis spectroscopy, cyclic voltammetry and single-crystal X-ray diffraction analysis. The crystallographic results showed that compound 1 represents silver(I) coordination polymer, in which 1,6-naph ligand acts as a bidentate bridging ligand connecting two Ag(I) ions via its N1 and N6 nitrogen atoms, while the third coordination site of the metal ion is occupied by the water oxygen atom, resulted in a T-shape geometry. Compounds 1 and 2 were evaluated in vitro for antimicrobial activity against five bacterial and two Candida species, while their cytotoxicity was tested on the normal human lung fibroblast cell line (MRC-5). Compound 1 has manifested a remarkable antifungal activity on both tested Candida strains (C. albicans and C. parapsilosis) with minimal inhibitory concentrations (MICs) of 1.43 and 11.38 µM (0.49 and 3.9 µg/mL), respectively, while no significant antimicrobial activity was observed for 2. Moreover, silver(I) coordination polymer 1 inhibits the hyphae formation of C. albicans at subinhibitory concentration. The binding affinity of both compounds 1 and 2 with calf thymus DNA (ct-DNA) and bovine serum albumin (BSA) was studied by fluorescence spectroscopy, indicating their ability to interact with these biomolecules, with compound 2 being more reactive.",
journal = "Polyhedron",
title = "Comparative study of antimicrobial potential and DNA/BSA binding affinity of silver(I) and gold(III) coordination compounds with 1,6-naphthyridine",
number = "1",
pages = "116585",
volume = "244",
doi = "10.1016/j.poly.2023.116585"
}

Ašanin, D., Andrejević, T., Nenadović, M., Rodić, M., Vojnović, S., Djuran, M.,& Glišić, B.. (2023). Comparative study of antimicrobial potential and DNA/BSA binding affinity of silver(I) and gold(III) coordination compounds with 1,6-naphthyridine. in Polyhedron, 244(1), 116585.
https://doi.org/10.1016/j.poly.2023.116585

Ašanin D, Andrejević T, Nenadović M, Rodić M, Vojnović S, Djuran M, Glišić B. Comparative study of antimicrobial potential and DNA/BSA binding affinity of silver(I) and gold(III) coordination compounds with 1,6-naphthyridine. in Polyhedron. 2023;244(1):116585.
doi:10.1016/j.poly.2023.116585 .

Ašanin, Darko, Andrejević, Tina, Nenadović, Marija, Rodić, Marko, Vojnović, Sandra, Djuran, Miloš, Glišić, Biljana, "Comparative study of antimicrobial potential and DNA/BSA binding affinity of silver(I) and gold(III) coordination compounds with 1,6-naphthyridine" in Polyhedron, 244, no. 1 (2023):116585,
https://doi.org/10.1016/j.poly.2023.116585 . .

TY  - JOUR
AU  - Ašanin, Darko
AU  - Andrejević, Tina
AU  - Nenadović, Marija
AU  - Rodić, Marko
AU  - Vojnović, Sandra
AU  - Djuran, Miloš
AU  - Glišić, Biljana
PY  - 2023
UR  - https://www.sciencedirect.com/science/article/pii/S0277538723003078
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/2076
AB  - In the present study, synthesis of silver(I) and gold(III) coordination compounds with 1,6-naphthyridine (1,6-naph), {[Ag(1,6-naph)(H2O)](BF4)}n (1) and [AuCl3(1,6-naph)] (2), was reported. The methods used for the structural characterization of a new compound 1 included IR, NMR (1H and 13C) and UV-Vis spectroscopy, cyclic voltammetry and single-crystal X-ray diffraction analysis. The crystallographic results showed that compound 1 represents silver(I) coordination polymer, in which 1,6-naph ligand acts as a bidentate bridging ligand connecting two Ag(I) ions via its N1 and N6 nitrogen atoms, while the third coordination site of the metal ion is occupied by the water oxygen atom, resulted in a T-shape geometry. Compounds 1 and 2 were evaluated in vitro for antimicrobial activity against five bacterial and two Candida species, while their cytotoxicity was tested on the normal human lung fibroblast cell line (MRC-5). Compound 1 has manifested a remarkable antifungal activity on both tested Candida strains (C. albicans and C. parapsilosis) with minimal inhibitory concentrations (MICs) of 1.43 and 11.38 µM (0.49 and 3.9 µg/mL), respectively, while no significant antimicrobial activity was observed for 2. Moreover, silver(I) coordination polymer 1 inhibits the hyphae formation of C. albicans at subinhibitory concentration. The binding affinity of both compounds 1 and 2 with calf thymus DNA (ct-DNA) and bovine serum albumin (BSA) was studied by fluorescence spectroscopy, indicating their ability to interact with these biomolecules, with compound 2 being more reactive.
T2  - Polyhedron
T1  - Comparative study of antimicrobial potential and DNA/BSA binding affinity of silver(I) and gold(III) coordination compounds with 1,6-naphthyridine
IS  - 1
SP  - 116585
VL  - 244
DO  - 10.1016/j.poly.2023.116585
ER  - 

@article{
author = "Ašanin, Darko and Andrejević, Tina and Nenadović, Marija and Rodić, Marko and Vojnović, Sandra and Djuran, Miloš and Glišić, Biljana",
year = "2023",
abstract = "In the present study, synthesis of silver(I) and gold(III) coordination compounds with 1,6-naphthyridine (1,6-naph), {[Ag(1,6-naph)(H2O)](BF4)}n (1) and [AuCl3(1,6-naph)] (2), was reported. The methods used for the structural characterization of a new compound 1 included IR, NMR (1H and 13C) and UV-Vis spectroscopy, cyclic voltammetry and single-crystal X-ray diffraction analysis. The crystallographic results showed that compound 1 represents silver(I) coordination polymer, in which 1,6-naph ligand acts as a bidentate bridging ligand connecting two Ag(I) ions via its N1 and N6 nitrogen atoms, while the third coordination site of the metal ion is occupied by the water oxygen atom, resulted in a T-shape geometry. Compounds 1 and 2 were evaluated in vitro for antimicrobial activity against five bacterial and two Candida species, while their cytotoxicity was tested on the normal human lung fibroblast cell line (MRC-5). Compound 1 has manifested a remarkable antifungal activity on both tested Candida strains (C. albicans and C. parapsilosis) with minimal inhibitory concentrations (MICs) of 1.43 and 11.38 µM (0.49 and 3.9 µg/mL), respectively, while no significant antimicrobial activity was observed for 2. Moreover, silver(I) coordination polymer 1 inhibits the hyphae formation of C. albicans at subinhibitory concentration. The binding affinity of both compounds 1 and 2 with calf thymus DNA (ct-DNA) and bovine serum albumin (BSA) was studied by fluorescence spectroscopy, indicating their ability to interact with these biomolecules, with compound 2 being more reactive.",
journal = "Polyhedron",
title = "Comparative study of antimicrobial potential and DNA/BSA binding affinity of silver(I) and gold(III) coordination compounds with 1,6-naphthyridine",
number = "1",
pages = "116585",
volume = "244",
doi = "10.1016/j.poly.2023.116585"
}

Ašanin, D., Andrejević, T., Nenadović, M., Rodić, M., Vojnović, S., Djuran, M.,& Glišić, B.. (2023). Comparative study of antimicrobial potential and DNA/BSA binding affinity of silver(I) and gold(III) coordination compounds with 1,6-naphthyridine. in Polyhedron, 244(1), 116585.
https://doi.org/10.1016/j.poly.2023.116585

Ašanin D, Andrejević T, Nenadović M, Rodić M, Vojnović S, Djuran M, Glišić B. Comparative study of antimicrobial potential and DNA/BSA binding affinity of silver(I) and gold(III) coordination compounds with 1,6-naphthyridine. in Polyhedron. 2023;244(1):116585.
doi:10.1016/j.poly.2023.116585 .

Ašanin, Darko, Andrejević, Tina, Nenadović, Marija, Rodić, Marko, Vojnović, Sandra, Djuran, Miloš, Glišić, Biljana, "Comparative study of antimicrobial potential and DNA/BSA binding affinity of silver(I) and gold(III) coordination compounds with 1,6-naphthyridine" in Polyhedron, 244, no. 1 (2023):116585,
https://doi.org/10.1016/j.poly.2023.116585 . .

TY  - JOUR
AU  - Svircev, Milos
AU  - Popsavin, Mirjana
AU  - Pavić, Aleksandar
AU  - Vasiljević, Branka
AU  - Rodić, Marko V.
AU  - Đokić, Sanja
AU  - Kesić, Jelena
AU  - Sreco Zelenović, Bojana
AU  - Popsavin, Velimir
AU  - Kojić, Vesna
PY  - 2022
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1561
AB  - The synthesis of several new goniofufurone bioisosteres was achieved in which the phenyl residue was replaced by a thiazole ring. The key steps of the synthesis included the initial condensation of cyanohydrin benzoates with cysteine ethyl ester hydrochloride, followed by the subsequent reaction of resulting C-4 ' epimeric thiazolines with DBU, to introduce 5-deoxy functionality and to elaborate the thiazole ring in one step. Synthesized compounds showed potent growth inhibitory effects against selected human tumour cell lines, especially bioisostere 4, which in the culture of MCF-7 cells displayed the highest activity (IC50 = 0.19 nM) of all compounds under evaluation. This molecule exhibited 64474-fold higher antiproliferative activity than lead 2 and was1053-fold more active than the commercial antitumour agent doxorubicin in the culture of MCF-7 cells. The structural features of the tested compounds responsible for their antiproliferative activity have been identified by preliminary SAR analysis. The toxicity of the most active compound 4 was assessed by an in vivo experiment in a zebrafish model (Danio rerio), whereupon it was found non-toxic at any of the tested concentrations up to 125 mu M.
PB  - Academic Press Inc Elsevier Science, San Diego
T2  - Bioorganic Chemistry
T1  - Design, synthesis, and biological evaluation of thiazole bioisosteres of goniofufurone through in vitro antiproliferative activity and in vivo toxicity
VL  - 121
DO  - 10.1016/j.bioorg.2022.105691
ER  - 

@article{
author = "Svircev, Milos and Popsavin, Mirjana and Pavić, Aleksandar and Vasiljević, Branka and Rodić, Marko V. and Đokić, Sanja and Kesić, Jelena and Sreco Zelenović, Bojana and Popsavin, Velimir and Kojić, Vesna",
year = "2022",
abstract = "The synthesis of several new goniofufurone bioisosteres was achieved in which the phenyl residue was replaced by a thiazole ring. The key steps of the synthesis included the initial condensation of cyanohydrin benzoates with cysteine ethyl ester hydrochloride, followed by the subsequent reaction of resulting C-4 ' epimeric thiazolines with DBU, to introduce 5-deoxy functionality and to elaborate the thiazole ring in one step. Synthesized compounds showed potent growth inhibitory effects against selected human tumour cell lines, especially bioisostere 4, which in the culture of MCF-7 cells displayed the highest activity (IC50 = 0.19 nM) of all compounds under evaluation. This molecule exhibited 64474-fold higher antiproliferative activity than lead 2 and was1053-fold more active than the commercial antitumour agent doxorubicin in the culture of MCF-7 cells. The structural features of the tested compounds responsible for their antiproliferative activity have been identified by preliminary SAR analysis. The toxicity of the most active compound 4 was assessed by an in vivo experiment in a zebrafish model (Danio rerio), whereupon it was found non-toxic at any of the tested concentrations up to 125 mu M.",
publisher = "Academic Press Inc Elsevier Science, San Diego",
journal = "Bioorganic Chemistry",
title = "Design, synthesis, and biological evaluation of thiazole bioisosteres of goniofufurone through in vitro antiproliferative activity and in vivo toxicity",
volume = "121",
doi = "10.1016/j.bioorg.2022.105691"
}

Svircev, M., Popsavin, M., Pavić, A., Vasiljević, B., Rodić, M. V., Đokić, S., Kesić, J., Sreco Zelenović, B., Popsavin, V.,& Kojić, V.. (2022). Design, synthesis, and biological evaluation of thiazole bioisosteres of goniofufurone through in vitro antiproliferative activity and in vivo toxicity. in Bioorganic Chemistry
Academic Press Inc Elsevier Science, San Diego., 121.
https://doi.org/10.1016/j.bioorg.2022.105691

Svircev M, Popsavin M, Pavić A, Vasiljević B, Rodić MV, Đokić S, Kesić J, Sreco Zelenović B, Popsavin V, Kojić V. Design, synthesis, and biological evaluation of thiazole bioisosteres of goniofufurone through in vitro antiproliferative activity and in vivo toxicity. in Bioorganic Chemistry. 2022;121.
doi:10.1016/j.bioorg.2022.105691 .

Svircev, Milos, Popsavin, Mirjana, Pavić, Aleksandar, Vasiljević, Branka, Rodić, Marko V., Đokić, Sanja, Kesić, Jelena, Sreco Zelenović, Bojana, Popsavin, Velimir, Kojić, Vesna, "Design, synthesis, and biological evaluation of thiazole bioisosteres of goniofufurone through in vitro antiproliferative activity and in vivo toxicity" in Bioorganic Chemistry, 121 (2022),
https://doi.org/10.1016/j.bioorg.2022.105691 . .

TY  - JOUR
AU  - Đokić, S.
AU  - Francuz, J.
AU  - Popsavin, M.
AU  - Rodić, M.V.
AU  - Kojić, V.
AU  - Stevanović, Milena
AU  - Popsavin, V.
PY  - 2022
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1546
AB  - Synthesis of protulactone A (PLA, 1) and twelve of its analogues have been achieved starting from D-galactose. PLA was isolated in the crystalline state, and its crystal structure was determined utilizing X-ray crystallography, which confirmed the assumed stereochemistry at all stereocenters. All tested compounds displayed antiproliferative activity against a panel of tumour cell lines, and all of them were non-cytotoxic toward the normal cells (MRC-5). Natural product PLA (1) was the most active against the K562 and MCF-7 cell lines (IC50 6.52 and 2.20 μM, respectively). Some of the synthesized derivatives showed very potent cytotoxicity, especially analogues 11, 13 and 15 (IC50 1.08–1.14 μM against MCF-7), and 9 and 14 (IC50 1.29 and 1.64 μM against K562). SAR analysis indicated important structural motifs for antiproliferative activity. Unfortunately, PLA (1), its C-7 epimer (2) and demethylated analogue (3) did not display a significant antimicrobial activity (two Gram-positive and two Gram-negative bacteria and one fungal strain) and they also cannot affect the ability to modulate bacterial communication.
PB  - Academic Press Inc.
T2  - Bioorganic Chemistry
T1  - Natural product protulactone A: Total synthesis from D-galactose, X-ray analysis and biological evaluation
VL  - 127
DO  - 10.1016/j.bioorg.2022.105980
ER  - 

@article{
author = "Đokić, S. and Francuz, J. and Popsavin, M. and Rodić, M.V. and Kojić, V. and Stevanović, Milena and Popsavin, V.",
year = "2022",
abstract = "Synthesis of protulactone A (PLA, 1) and twelve of its analogues have been achieved starting from D-galactose. PLA was isolated in the crystalline state, and its crystal structure was determined utilizing X-ray crystallography, which confirmed the assumed stereochemistry at all stereocenters. All tested compounds displayed antiproliferative activity against a panel of tumour cell lines, and all of them were non-cytotoxic toward the normal cells (MRC-5). Natural product PLA (1) was the most active against the K562 and MCF-7 cell lines (IC50 6.52 and 2.20 μM, respectively). Some of the synthesized derivatives showed very potent cytotoxicity, especially analogues 11, 13 and 15 (IC50 1.08–1.14 μM against MCF-7), and 9 and 14 (IC50 1.29 and 1.64 μM against K562). SAR analysis indicated important structural motifs for antiproliferative activity. Unfortunately, PLA (1), its C-7 epimer (2) and demethylated analogue (3) did not display a significant antimicrobial activity (two Gram-positive and two Gram-negative bacteria and one fungal strain) and they also cannot affect the ability to modulate bacterial communication.",
publisher = "Academic Press Inc.",
journal = "Bioorganic Chemistry",
title = "Natural product protulactone A: Total synthesis from D-galactose, X-ray analysis and biological evaluation",
volume = "127",
doi = "10.1016/j.bioorg.2022.105980"
}

Đokić, S., Francuz, J., Popsavin, M., Rodić, M.V., Kojić, V., Stevanović, M.,& Popsavin, V.. (2022). Natural product protulactone A: Total synthesis from D-galactose, X-ray analysis and biological evaluation. in Bioorganic Chemistry
Academic Press Inc.., 127.
https://doi.org/10.1016/j.bioorg.2022.105980

Đokić S, Francuz J, Popsavin M, Rodić M, Kojić V, Stevanović M, Popsavin V. Natural product protulactone A: Total synthesis from D-galactose, X-ray analysis and biological evaluation. in Bioorganic Chemistry. 2022;127.
doi:10.1016/j.bioorg.2022.105980 .

Đokić, S., Francuz, J., Popsavin, M., Rodić, M.V., Kojić, V., Stevanović, Milena, Popsavin, V., "Natural product protulactone A: Total synthesis from D-galactose, X-ray analysis and biological evaluation" in Bioorganic Chemistry, 127 (2022),
https://doi.org/10.1016/j.bioorg.2022.105980 . .

TY  - CHAP
AU  - Djisalov, Mila
AU  - Knežić, Teodora
AU  - Janjušević, Ljiljana
AU  - Popović, Željko
AU  - Kosijer, Petar
AU  - Gadjanski, Ivana
PY  - 2021
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1724
AB  - Pravovremeno testiranje većeg broja ljudi na SARS-CoV-2 virus je povezano sa nižim mortalitetom od
COVID-19 oboljenja. Međutim, većina zemalja nema mogućnosti za takvo masivno testiranje putem metode
“PCR u realnom vremenu”, zbog visoke cene neophodne opreme i potrebe za stručnim osobljem.
Zbog toga se razvijaju brze i ekonomičnije metode, koje se najčešće zasnivaju na izotermalnim metodama
amplifikacije DNK. Za ove metode nije potreban ciklični termostat, zbog čega su primenljivije za
terensku upotrebu. Fokus je na izotermalnoj amplifikaciji posredovanoj petljom (lamP), zbog njene
visoke specifičnosti, mogućnosti za upotrebu neprečišćenih uzoraka i jednostavnosti merenja signala. Autori
predstavljaju pregled najvažnijih radova o LAMP metodi za detekciju SARS-CoV-2 virusa objavljenih
tokom 2020. godine, kao i opise nekoliko komercijalnih kompleta na bazi LAMP metode za COVID-19 testiranje.
AB  - Massive testing for SARS-CoV-2 virus is related to lower mortality rates of COVID-19. Most countries face
challenges to perform massive testing with the currently available methods (real-time PCR), due to expensive
equipment and requirement of highly skilled personnel. To overcome these challenges, faster
and cost-effective alternative detection methods are being developed, primarily based on isothermal
methods of nucleic acid amplification (isoNAAs). PCR depends on precision instruments, high cleanliness
of operating conditions and cannot be easily used on-site, while isoNAAs, which do not require
thermal cyclers, are more applicable for point-of-care (PoC) use. Loop-mediated isothermal amplification
(LAMP) is one of the isoNAA most in focus for COVID-19 tests due to its high specificity and possibility to
use unpurified specimens in combination with simplified detection setup. The article gives a review of
the most significant publications on use of LAMP for SARS-CoV-2 detection and of the several commercial
LAMP-based COVID-19 testing kits.
PB  - Beograd : Institut za molekularnu genetiku i genetičko inženjerstvo
T2  - Trendovi u molekularnoj Biologiji
T1  - Izotermalna amplifikacija posredovana petljom (lamP) kao metoda za terensku detekciju SarS-cov- virusa
T1  - loop-mediated isothermal amplification (lamP) as a point-of-care SarS-covdetection method
EP  - 32
SP  - 21
VL  - 1
UR  - https://hdl.handle.net/21.15107/rcub_imagine_1724
ER  - 

@inbook{
author = "Djisalov, Mila and Knežić, Teodora and Janjušević, Ljiljana and Popović, Željko and Kosijer, Petar and Gadjanski, Ivana",
year = "2021",
abstract = "Pravovremeno testiranje većeg broja ljudi na SARS-CoV-2 virus je povezano sa nižim mortalitetom od
COVID-19 oboljenja. Međutim, većina zemalja nema mogućnosti za takvo masivno testiranje putem metode
“PCR u realnom vremenu”, zbog visoke cene neophodne opreme i potrebe za stručnim osobljem.
Zbog toga se razvijaju brze i ekonomičnije metode, koje se najčešće zasnivaju na izotermalnim metodama
amplifikacije DNK. Za ove metode nije potreban ciklični termostat, zbog čega su primenljivije za
terensku upotrebu. Fokus je na izotermalnoj amplifikaciji posredovanoj petljom (lamP), zbog njene
visoke specifičnosti, mogućnosti za upotrebu neprečišćenih uzoraka i jednostavnosti merenja signala. Autori
predstavljaju pregled najvažnijih radova o LAMP metodi za detekciju SARS-CoV-2 virusa objavljenih
tokom 2020. godine, kao i opise nekoliko komercijalnih kompleta na bazi LAMP metode za COVID-19 testiranje., Massive testing for SARS-CoV-2 virus is related to lower mortality rates of COVID-19. Most countries face
challenges to perform massive testing with the currently available methods (real-time PCR), due to expensive
equipment and requirement of highly skilled personnel. To overcome these challenges, faster
and cost-effective alternative detection methods are being developed, primarily based on isothermal
methods of nucleic acid amplification (isoNAAs). PCR depends on precision instruments, high cleanliness
of operating conditions and cannot be easily used on-site, while isoNAAs, which do not require
thermal cyclers, are more applicable for point-of-care (PoC) use. Loop-mediated isothermal amplification
(LAMP) is one of the isoNAA most in focus for COVID-19 tests due to its high specificity and possibility to
use unpurified specimens in combination with simplified detection setup. The article gives a review of
the most significant publications on use of LAMP for SARS-CoV-2 detection and of the several commercial
LAMP-based COVID-19 testing kits.",
publisher = "Beograd : Institut za molekularnu genetiku i genetičko inženjerstvo",
journal = "Trendovi u molekularnoj Biologiji",
booktitle = "Izotermalna amplifikacija posredovana petljom (lamP) kao metoda za terensku detekciju SarS-cov- virusa, loop-mediated isothermal amplification (lamP) as a point-of-care SarS-covdetection method",
pages = "32-21",
volume = "1",
url = "https://hdl.handle.net/21.15107/rcub_imagine_1724"
}

Djisalov, M., Knežić, T., Janjušević, L., Popović, Ž., Kosijer, P.,& Gadjanski, I.. (2021). Izotermalna amplifikacija posredovana petljom (lamP) kao metoda za terensku detekciju SarS-cov- virusa. in Trendovi u molekularnoj Biologiji
Beograd : Institut za molekularnu genetiku i genetičko inženjerstvo., 1, 21-32.
https://hdl.handle.net/21.15107/rcub_imagine_1724

Djisalov M, Knežić T, Janjušević L, Popović Ž, Kosijer P, Gadjanski I. Izotermalna amplifikacija posredovana petljom (lamP) kao metoda za terensku detekciju SarS-cov- virusa. in Trendovi u molekularnoj Biologiji. 2021;1:21-32.
https://hdl.handle.net/21.15107/rcub_imagine_1724 .

Djisalov, Mila, Knežić, Teodora, Janjušević, Ljiljana, Popović, Željko, Kosijer, Petar, Gadjanski, Ivana, "Izotermalna amplifikacija posredovana petljom (lamP) kao metoda za terensku detekciju SarS-cov- virusa" in Trendovi u molekularnoj Biologiji, 1 (2021):21-32,
https://hdl.handle.net/21.15107/rcub_imagine_1724 .

TY  - JOUR
AU  - Stanić, Petar B.
AU  - Rodić, Marko, V
AU  - Soldatović, Tanja, V
AU  - Pavić, Aleksandar
AU  - Radaković, Nataša
AU  - Smit, Biljana M.
AU  - Živković, Marija D.
PY  - 2020
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1317
AB  - The 3-arylidene-2-thiohydantoin derivative, 3-[(2-hydroxybenzylidene)amino]-2-thioxoimidazolidin-4-one, was synthesized in a two-step condensation reaction of 2-hydroxybenzaldehyde, thiosemicarbazide and ethyl chloroacetate. The ligand was structurally characterized by NMR and IR spectroscopy, as well as by elemental analysis. In the reaction of the well-known polymeric trans-[CuCl2(DMSO)(2)](n) complex with the polydentate thiohydantoin type ligand, instead of the corresponding copper thiohydantoin complex, unexpectedly, the dinuclear cis-[{CuCl(DMSO)(2)}(mu-Cl)](2) complex (1) was formed predominantly as the final stable product. The structure of the complex 1 was confirmed by single crystal X-ray diffraction analysis. The cis-complex is obtained through assisted isomerization of the trans-form, in which the thiohydantoin derivative has a crucial role.
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - Reaction of a 3-aryilidene-2-thiohydantoin derivative with polymeric trans-[CuCl2(DMSO)(2)](n) complex: unexpected isomerization to dinuclear cis-[{CuCl(DMSO)(2)}(mu-Cl)](2)
EP  - 1603
IS  - 12
SP  - 1591
VL  - 85
DO  - 10.2298/JSC200917060S
ER  - 

@article{
author = "Stanić, Petar B. and Rodić, Marko, V and Soldatović, Tanja, V and Pavić, Aleksandar and Radaković, Nataša and Smit, Biljana M. and Živković, Marija D.",
year = "2020",
abstract = "The 3-arylidene-2-thiohydantoin derivative, 3-[(2-hydroxybenzylidene)amino]-2-thioxoimidazolidin-4-one, was synthesized in a two-step condensation reaction of 2-hydroxybenzaldehyde, thiosemicarbazide and ethyl chloroacetate. The ligand was structurally characterized by NMR and IR spectroscopy, as well as by elemental analysis. In the reaction of the well-known polymeric trans-[CuCl2(DMSO)(2)](n) complex with the polydentate thiohydantoin type ligand, instead of the corresponding copper thiohydantoin complex, unexpectedly, the dinuclear cis-[{CuCl(DMSO)(2)}(mu-Cl)](2) complex (1) was formed predominantly as the final stable product. The structure of the complex 1 was confirmed by single crystal X-ray diffraction analysis. The cis-complex is obtained through assisted isomerization of the trans-form, in which the thiohydantoin derivative has a crucial role.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "Reaction of a 3-aryilidene-2-thiohydantoin derivative with polymeric trans-[CuCl2(DMSO)(2)](n) complex: unexpected isomerization to dinuclear cis-[{CuCl(DMSO)(2)}(mu-Cl)](2)",
pages = "1603-1591",
number = "12",
volume = "85",
doi = "10.2298/JSC200917060S"
}

Stanić, P. B., Rodić, M. V., Soldatović, T. V., Pavić, A., Radaković, N., Smit, B. M.,& Živković, M. D.. (2020). Reaction of a 3-aryilidene-2-thiohydantoin derivative with polymeric trans-[CuCl2(DMSO)(2)](n) complex: unexpected isomerization to dinuclear cis-[{CuCl(DMSO)(2)}(mu-Cl)](2). in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 85(12), 1591-1603.
https://doi.org/10.2298/JSC200917060S

Stanić PB, Rodić MV, Soldatović TV, Pavić A, Radaković N, Smit BM, Živković MD. Reaction of a 3-aryilidene-2-thiohydantoin derivative with polymeric trans-[CuCl2(DMSO)(2)](n) complex: unexpected isomerization to dinuclear cis-[{CuCl(DMSO)(2)}(mu-Cl)](2). in Journal of the Serbian Chemical Society. 2020;85(12):1591-1603.
doi:10.2298/JSC200917060S .

Stanić, Petar B., Rodić, Marko, V, Soldatović, Tanja, V, Pavić, Aleksandar, Radaković, Nataša, Smit, Biljana M., Živković, Marija D., "Reaction of a 3-aryilidene-2-thiohydantoin derivative with polymeric trans-[CuCl2(DMSO)(2)](n) complex: unexpected isomerization to dinuclear cis-[{CuCl(DMSO)(2)}(mu-Cl)](2)" in Journal of the Serbian Chemical Society, 85, no. 12 (2020):1591-1603,
https://doi.org/10.2298/JSC200917060S . .

TY  - JOUR
AU  - Gitarić, Jelena
AU  - Stanojević, Ivana M.
AU  - Rodić, Marko, V
AU  - Drasković, Nenad S.
AU  - Stevanović, Milena
AU  - Vojnović, Sandra
AU  - Djuran, Milos
AU  - Glišić, Biljana
PY  - 2020
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1352
AB  - New polynuclear manganese(II) and cadmium(II) complexes with 2,2-dimethyl-1,3-propanediamine-N,N, N',N'-tetraacetato ligand (2,2-diMe-1,3-pdta), {Ba[M(2,2-diMe-1,3-pdta)]center dot 3H(2)O}(n) (M = Mn (1) or Cd (2)) were synthesized and characterized by IR spectroscopy and single-crystal X-ray diffraction analysis. In addition, complex 2 was characterized by solution H-1 and C-13 NMR spectroscopy. Crystallographic analysis showed that 2,2-diMe-1,3-pdta ligand is hexadentately coordinated to each M(II) ion through the two nitrogen and four carboxylate oxygen atoms, whereas the one of these oxygen atoms is also involved in coordination to the second M(II) ion of the dinuclear [M-2(2,2-diMe-1,3-pdta)(2)](4-) unit in polymeric structures. Moreover, three of four carboxylic groups of 2,2-diMe-1,3-pdta ligand are additionally bonded to four Ba(II) ions, in three distinctive bridging coordination modes. Each Ba(II) ion is surrounded by ten oxygen atoms, seven belonging to carboxylate groups of 2,2-diMe-1,3-pdta, and three belonging to water molecules. The coordination environment around Mn(II) and Cd(II) ions could be assigned as a face capped octahedron, while coordination polyhedron around Ba(II) ion in these two complexes was described as a distorted sphenocorona. The antimicrobial potential of complexes 1 and 2 and corresponding metal salts used for their synthesis was evaluated against different bacterial and Candida spp. Both complexes showed selective antifungal activity against the tested Candida spp. compared to the bacterial strains, with the minimal inhibitory concentration (MIC) values in the range 3.12 - 12.50 mu M. Moreover, complex 1 caused the slightly decrease of hyphae length, while no significant influence on hyphal length of complex 2 was observed. With aim to assess the therapeutic profile of the complexes, their cytotoxicity was evaluated against the normal human lung fibroblast cell line (MRC-5).
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Polyhedron
T1  - Structural characterization and biological evaluation of polynuclear Mn (II) and Cd(II) complexes with 2,2-dimethyl-1,3-propanediamine-N,N,N ', N '-tetraacetate. The influence of ligand structure and counter cation on the complex nuclearity
VL  - 188
DO  - 10.1016/j.poly.2020.114688
ER  - 

@article{
author = "Gitarić, Jelena and Stanojević, Ivana M. and Rodić, Marko, V and Drasković, Nenad S. and Stevanović, Milena and Vojnović, Sandra and Djuran, Milos and Glišić, Biljana",
year = "2020",
abstract = "New polynuclear manganese(II) and cadmium(II) complexes with 2,2-dimethyl-1,3-propanediamine-N,N, N',N'-tetraacetato ligand (2,2-diMe-1,3-pdta), {Ba[M(2,2-diMe-1,3-pdta)]center dot 3H(2)O}(n) (M = Mn (1) or Cd (2)) were synthesized and characterized by IR spectroscopy and single-crystal X-ray diffraction analysis. In addition, complex 2 was characterized by solution H-1 and C-13 NMR spectroscopy. Crystallographic analysis showed that 2,2-diMe-1,3-pdta ligand is hexadentately coordinated to each M(II) ion through the two nitrogen and four carboxylate oxygen atoms, whereas the one of these oxygen atoms is also involved in coordination to the second M(II) ion of the dinuclear [M-2(2,2-diMe-1,3-pdta)(2)](4-) unit in polymeric structures. Moreover, three of four carboxylic groups of 2,2-diMe-1,3-pdta ligand are additionally bonded to four Ba(II) ions, in three distinctive bridging coordination modes. Each Ba(II) ion is surrounded by ten oxygen atoms, seven belonging to carboxylate groups of 2,2-diMe-1,3-pdta, and three belonging to water molecules. The coordination environment around Mn(II) and Cd(II) ions could be assigned as a face capped octahedron, while coordination polyhedron around Ba(II) ion in these two complexes was described as a distorted sphenocorona. The antimicrobial potential of complexes 1 and 2 and corresponding metal salts used for their synthesis was evaluated against different bacterial and Candida spp. Both complexes showed selective antifungal activity against the tested Candida spp. compared to the bacterial strains, with the minimal inhibitory concentration (MIC) values in the range 3.12 - 12.50 mu M. Moreover, complex 1 caused the slightly decrease of hyphae length, while no significant influence on hyphal length of complex 2 was observed. With aim to assess the therapeutic profile of the complexes, their cytotoxicity was evaluated against the normal human lung fibroblast cell line (MRC-5).",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Polyhedron",
title = "Structural characterization and biological evaluation of polynuclear Mn (II) and Cd(II) complexes with 2,2-dimethyl-1,3-propanediamine-N,N,N ', N '-tetraacetate. The influence of ligand structure and counter cation on the complex nuclearity",
volume = "188",
doi = "10.1016/j.poly.2020.114688"
}

Gitarić, J., Stanojević, I. M., Rodić, M. V., Drasković, N. S., Stevanović, M., Vojnović, S., Djuran, M.,& Glišić, B.. (2020). Structural characterization and biological evaluation of polynuclear Mn (II) and Cd(II) complexes with 2,2-dimethyl-1,3-propanediamine-N,N,N ', N '-tetraacetate. The influence of ligand structure and counter cation on the complex nuclearity. in Polyhedron
Pergamon-Elsevier Science Ltd, Oxford., 188.
https://doi.org/10.1016/j.poly.2020.114688

Gitarić J, Stanojević IM, Rodić MV, Drasković NS, Stevanović M, Vojnović S, Djuran M, Glišić B. Structural characterization and biological evaluation of polynuclear Mn (II) and Cd(II) complexes with 2,2-dimethyl-1,3-propanediamine-N,N,N ', N '-tetraacetate. The influence of ligand structure and counter cation on the complex nuclearity. in Polyhedron. 2020;188.
doi:10.1016/j.poly.2020.114688 .

Gitarić, Jelena, Stanojević, Ivana M., Rodić, Marko, V, Drasković, Nenad S., Stevanović, Milena, Vojnović, Sandra, Djuran, Milos, Glišić, Biljana, "Structural characterization and biological evaluation of polynuclear Mn (II) and Cd(II) complexes with 2,2-dimethyl-1,3-propanediamine-N,N,N ', N '-tetraacetate. The influence of ligand structure and counter cation on the complex nuclearity" in Polyhedron, 188 (2020),
https://doi.org/10.1016/j.poly.2020.114688 . .