Search
Now showing items 1-7 of 7
Cytotoxic effect of Reseda lutea L.: A case of forgotten remedy
(Elsevier Ireland Ltd, Clare, 2014)
Ethnopharmacological relevance: Reseda lutea L (Resedaceae) or Wild Mignonette is a widely distributed plant species. Pliny the Elder (AD 23-AD 79), a Roman scholar and naturalist, reported the use of R. lutea for reducing ...
Induction of caspase-independent apoptotic-like cell death of mouse mammary tumor TA3Ha cells in vitro and reduction of their lethality in vivo by the novel chemotherapeutic agent GIT-27NO
(Elsevier Science Inc, New York, 2010)
The new chemical entity GIT-27NO was created by the covalent linkage of a NO moiety to the antiinflammatory isoxazoline VGX-1027 The compound has been shown to possess powerful anticancer effects both in vitro and in vivo ...
Targeting autophagy to modulate cell survival: a comparative analysis in cancer, normal and embryonic cells
(Springer, New York, 2017)
Autophagy is linked to multiple cancer-related signaling pathways, and represents a defense mechanism for cancer cells under therapeutic stress. The crosstalk between apoptosis and autophagy is essential for both tumorigenesis ...
Overexpression of the novel member of the BCL2 gene family, BCL2L12, is associated with the disease outcome in patients with acute myeloid leukemia
(Pergamon-Elsevier Science Ltd, Oxford, 2012)
Objectives: BCL2L12 is a recently discovered and cloned gene from members of our research team. It is a novel member of the BCL2 gene family, members of which are implicated in different hematological malignancies. In the ...
Pd(II) complexes with N-heteroaromatic hydrazone ligands: Anticancer activity, in silico and experimental target identification
(Elsevier Science Inc, New York, 2019)
Anticancer activity of Pd complexes 1-5 with bidentate N-heteroaromatic hydrazone ligands was investigated on human acute monocytic leukemia (THP-1; cells in a suspension) and human mammary adenocarcinoma (MCF-7; two-dimensional ...
Targeting autophagy to modulate cell survival: a comparative analysis in cancer, normal and embryonic cells
(Springer, New York, 2017)
Autophagy is linked to multiple cancer-related signaling pathways, and represents a defense mechanism for cancer cells under therapeutic stress. The crosstalk between apoptosis and autophagy is essential for both tumorigenesis ...
Chemical composition of the mushroom Meripilus giganteus Karst. and bioactive properties of its methanolic extract
(Elsevier Science Bv, Amsterdam, 2017)
Wild Meripilus giganteus Karst belongs to the order Polyporales, in which some members are known to possess a wide range of pharmacological properties. M. giganteus showed to be rich in carbohydrates (74.49 g/100 g) and ...