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Amide containing NBTI antibacterials with reduced hERG inhibition, retained antimicrobial activity against gram-positive bacteria and in vivo efficacy
(European Journal of Medicinal ChemistryEuropean Journal of Medicinal ChemistryEuropean Journal of Medicinal Chemistry, 2023)
Novel bacterial topoisomerase inhibitors (NBTIs) are new promising antimicrobials for the treatment of multidrug-resistant bacterial infections. In recent years, many new NBTIs have been discovered, however most of them ...