Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites
Аутори
Malagurski, IvanaLević, Steva
Pantić, Milena
Matijašević, Danka
Mitrić, Miodrag
Pavlović, Vladimir
Dimitrijević-Branković, Suzana
Чланак у часопису (Рецензирана верзија)
Метаподаци
Приказ свих података о документуАпстракт
New bioactive and antimicrobial biomaterials were produced by alginate-mediated biomineralization with Zn-mineral phase. The synthesis procedure is simple, cost-effective and resulted in. two different Zn-mineralized alginate nanocomposites, Zn-carbonate/Zn-alginate and Zn-phosphate/Zn-alginate. The presence of Zn-mineral phase and its type, have significantly affected nanocomposite morphology, stability, total metallic loading and potential to release Zn(II) in physiological environment. Antimicrobial experiments showed that both types of Zn-mineralized nanocomposites exhibit strong antimicrobial effect against Escherichia coli, Staphylococcus aureus and Candida albicans. These results suggest that alginate biomineralization, where minerals are salts of essential metallic ions like Zn(II), represents a'good strategy for designing multifunctional biomaterials for potential biomedical applications.
Кључне речи:
Zinc / Nanocomposite / Biomineralization / Antimicrobial activity / AlginateИзвор:
Carbohydrate Polymers, 2017, 165, 313-321Издавач:
- Elsevier Sci Ltd, Oxford
Финансирање / пројекти:
- Синтеза, развој технологија добијања и примена наноструктурних мултифункционалних материјала дефинисаних својстава (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45019)
- Усмерена синтеза, структура и својства мултифункционалних материјала (RS-MESTD-Basic Research (BR or ON)-172057)
Напомена:
- This is the peer reviewed version of the paper: Malagurski, I., Levic, S., Pantic, M., Matijasevic, D., Mitric, M., Pavlovic, V., & Dimitrijevic-Brankovic, S. (2017). Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites. Carbohydrate Polymers, 165, 313–321. https://doi.org/10.1016/j.carbpol.2017.02.064
Повезане информације:
- Друга верзија
https://doi.org/10.1016/j.carbpol.2017.02.064
DOI: 10.1016/j.carbpol.2017.02.064
ISSN: 0144-8617
PubMed: 28363555
WoS: 000399261900035
Scopus: 2-s2.0-85013763459
Институција/група
Institut za molekularnu genetiku i genetičko inženjerstvoTY - JOUR AU - Malagurski, Ivana AU - Lević, Steva AU - Pantić, Milena AU - Matijašević, Danka AU - Mitrić, Miodrag AU - Pavlović, Vladimir AU - Dimitrijević-Branković, Suzana PY - 2017 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/1054 AB - New bioactive and antimicrobial biomaterials were produced by alginate-mediated biomineralization with Zn-mineral phase. The synthesis procedure is simple, cost-effective and resulted in. two different Zn-mineralized alginate nanocomposites, Zn-carbonate/Zn-alginate and Zn-phosphate/Zn-alginate. The presence of Zn-mineral phase and its type, have significantly affected nanocomposite morphology, stability, total metallic loading and potential to release Zn(II) in physiological environment. Antimicrobial experiments showed that both types of Zn-mineralized nanocomposites exhibit strong antimicrobial effect against Escherichia coli, Staphylococcus aureus and Candida albicans. These results suggest that alginate biomineralization, where minerals are salts of essential metallic ions like Zn(II), represents a'good strategy for designing multifunctional biomaterials for potential biomedical applications. PB - Elsevier Sci Ltd, Oxford T2 - Carbohydrate Polymers T1 - Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites EP - 321 SP - 313 VL - 165 DO - 10.1016/j.carbpol.2017.02.064 ER -
@article{ author = "Malagurski, Ivana and Lević, Steva and Pantić, Milena and Matijašević, Danka and Mitrić, Miodrag and Pavlović, Vladimir and Dimitrijević-Branković, Suzana", year = "2017", abstract = "New bioactive and antimicrobial biomaterials were produced by alginate-mediated biomineralization with Zn-mineral phase. The synthesis procedure is simple, cost-effective and resulted in. two different Zn-mineralized alginate nanocomposites, Zn-carbonate/Zn-alginate and Zn-phosphate/Zn-alginate. The presence of Zn-mineral phase and its type, have significantly affected nanocomposite morphology, stability, total metallic loading and potential to release Zn(II) in physiological environment. Antimicrobial experiments showed that both types of Zn-mineralized nanocomposites exhibit strong antimicrobial effect against Escherichia coli, Staphylococcus aureus and Candida albicans. These results suggest that alginate biomineralization, where minerals are salts of essential metallic ions like Zn(II), represents a'good strategy for designing multifunctional biomaterials for potential biomedical applications.", publisher = "Elsevier Sci Ltd, Oxford", journal = "Carbohydrate Polymers", title = "Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites", pages = "321-313", volume = "165", doi = "10.1016/j.carbpol.2017.02.064" }
Malagurski, I., Lević, S., Pantić, M., Matijašević, D., Mitrić, M., Pavlović, V.,& Dimitrijević-Branković, S.. (2017). Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites. in Carbohydrate Polymers Elsevier Sci Ltd, Oxford., 165, 313-321. https://doi.org/10.1016/j.carbpol.2017.02.064
Malagurski I, Lević S, Pantić M, Matijašević D, Mitrić M, Pavlović V, Dimitrijević-Branković S. Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites. in Carbohydrate Polymers. 2017;165:313-321. doi:10.1016/j.carbpol.2017.02.064 .
Malagurski, Ivana, Lević, Steva, Pantić, Milena, Matijašević, Danka, Mitrić, Miodrag, Pavlović, Vladimir, Dimitrijević-Branković, Suzana, "Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites" in Carbohydrate Polymers, 165 (2017):313-321, https://doi.org/10.1016/j.carbpol.2017.02.064 . .