Positioning Europe for the EPITRANSCRIPTOMICS challenge
2018
Preuzimanje 🢃
Autori
Jantsch, Michael F.Quattrone, Alessandro
O'Connell, Mary
Helm, Mark
Frye, Michaela
Macias-Gonzales, Manuel
Ohman, Marie
Ameres, Stefan
Willems, Luc
Fuks, Francois
Oulas, Anastasis
Vanacova, Stepanka
Nielsen, Henrik
Bousquet-Antonelli, Cecile
Motorin, Yuri
Roignant, Jean-Yves
Balatsos, Nikolaos
Dinnyes, Andras
Baranov, Pavel
Kelly, Vincent
Lamm, Ayelet
Rechavi, Gideon
Pelizzola, Mattia
Liepins, Janis
Kholodnyuk, Irina Holodnuka
Zammit, Vanessa
Ayers, Duncan
Drablos, Finn
Dahl, John Arne
Bujnicki, Janusz
Jeronimo, Carmen
Almeida, Raquel
Neagu, Monica
Costache, Marieta
Banković, Jasna
Banović Đeri, Bojana
Kyselovic, Jan
Valor, Luis Miguel
Selbert, Stefan
Pir, Pinar
Demircan, Turan
Cowling, Victoria
Schaefer, Matthias
Rossmanith, Walter
Lafontaine, Denis
David, Alexandre
Carre, Clement
Lyko, Frank
Schaffrath, Raffael
Schwartz, Schraga
Verdel, Andre
Klungland, Arne
Purta, Elzbieta
Timotijević, Gordana
Cardona, Fernando
Davalos, Alberto
Ballana, Ester
O'Carroll, Donal
Ule, Jernej
Fray, Rupert
Informativni prilog (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The genetic alphabet consists of the four letters: C, A, G, and T in DNA and C,A,G, and U in RNA. Triplets of these four letters jointly encode 20 different amino acids out of which proteins of all organisms are built. This system is universal and is found in all kingdoms of life. However, bases in DNA and RNA can be chemically modified. In DNA, around 10 different modifications are known, and those have been studied intensively over the past 20years. Scientific studies on DNA modifications and proteins that recognize them gave rise to the large field of epigenetic and epigenomic research. The outcome of this intense research field is the discovery that development, ageing, and stem-cell dependent regeneration but also several diseases including cancer are largely controlled by the epigenetic state of cells. Consequently, this research has already led to the first FDA approved drugs that exploit the gained knowledge to combat disease. In recent years, the similar to 150 modifications f...ound in RNA have come to the focus of intense research. Here we provide a perspective on necessary and expected developments in the fast expanding area of RNA modifications, termed epitranscriptomics.
Ključne reči:
model systems / European funding / epitranscriptomics / detection of RNA modification / database of ModificationIzvor:
RNA Biology, 2018, 15, 6, 829-831Izdavač:
- Taylor & Francis Inc, Philadelphia
Finansiranje / projekti:
- COST Action [CA16120]
- MRC [MR/M01939X/1, G0801904, MR/K024213/1] Funding Source: UKRI
DOI: 10.1080/15476286.2018.1460996
ISSN: 1547-6286
PubMed: 29671387
WoS: 000444092300018
Scopus: 2-s2.0-85046696156
Institucija/grupa
Institut za molekularnu genetiku i genetičko inženjerstvoTY - JOUR AU - Jantsch, Michael F. AU - Quattrone, Alessandro AU - O'Connell, Mary AU - Helm, Mark AU - Frye, Michaela AU - Macias-Gonzales, Manuel AU - Ohman, Marie AU - Ameres, Stefan AU - Willems, Luc AU - Fuks, Francois AU - Oulas, Anastasis AU - Vanacova, Stepanka AU - Nielsen, Henrik AU - Bousquet-Antonelli, Cecile AU - Motorin, Yuri AU - Roignant, Jean-Yves AU - Balatsos, Nikolaos AU - Dinnyes, Andras AU - Baranov, Pavel AU - Kelly, Vincent AU - Lamm, Ayelet AU - Rechavi, Gideon AU - Pelizzola, Mattia AU - Liepins, Janis AU - Kholodnyuk, Irina Holodnuka AU - Zammit, Vanessa AU - Ayers, Duncan AU - Drablos, Finn AU - Dahl, John Arne AU - Bujnicki, Janusz AU - Jeronimo, Carmen AU - Almeida, Raquel AU - Neagu, Monica AU - Costache, Marieta AU - Banković, Jasna AU - Banović Đeri, Bojana AU - Kyselovic, Jan AU - Valor, Luis Miguel AU - Selbert, Stefan AU - Pir, Pinar AU - Demircan, Turan AU - Cowling, Victoria AU - Schaefer, Matthias AU - Rossmanith, Walter AU - Lafontaine, Denis AU - David, Alexandre AU - Carre, Clement AU - Lyko, Frank AU - Schaffrath, Raffael AU - Schwartz, Schraga AU - Verdel, Andre AU - Klungland, Arne AU - Purta, Elzbieta AU - Timotijević, Gordana AU - Cardona, Fernando AU - Davalos, Alberto AU - Ballana, Ester AU - O'Carroll, Donal AU - Ule, Jernej AU - Fray, Rupert PY - 2018 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/1100 AB - The genetic alphabet consists of the four letters: C, A, G, and T in DNA and C,A,G, and U in RNA. Triplets of these four letters jointly encode 20 different amino acids out of which proteins of all organisms are built. This system is universal and is found in all kingdoms of life. However, bases in DNA and RNA can be chemically modified. In DNA, around 10 different modifications are known, and those have been studied intensively over the past 20years. Scientific studies on DNA modifications and proteins that recognize them gave rise to the large field of epigenetic and epigenomic research. The outcome of this intense research field is the discovery that development, ageing, and stem-cell dependent regeneration but also several diseases including cancer are largely controlled by the epigenetic state of cells. Consequently, this research has already led to the first FDA approved drugs that exploit the gained knowledge to combat disease. In recent years, the similar to 150 modifications found in RNA have come to the focus of intense research. Here we provide a perspective on necessary and expected developments in the fast expanding area of RNA modifications, termed epitranscriptomics. PB - Taylor & Francis Inc, Philadelphia T2 - RNA Biology T1 - Positioning Europe for the EPITRANSCRIPTOMICS challenge EP - 831 IS - 6 SP - 829 VL - 15 DO - 10.1080/15476286.2018.1460996 ER -
@article{ author = "Jantsch, Michael F. and Quattrone, Alessandro and O'Connell, Mary and Helm, Mark and Frye, Michaela and Macias-Gonzales, Manuel and Ohman, Marie and Ameres, Stefan and Willems, Luc and Fuks, Francois and Oulas, Anastasis and Vanacova, Stepanka and Nielsen, Henrik and Bousquet-Antonelli, Cecile and Motorin, Yuri and Roignant, Jean-Yves and Balatsos, Nikolaos and Dinnyes, Andras and Baranov, Pavel and Kelly, Vincent and Lamm, Ayelet and Rechavi, Gideon and Pelizzola, Mattia and Liepins, Janis and Kholodnyuk, Irina Holodnuka and Zammit, Vanessa and Ayers, Duncan and Drablos, Finn and Dahl, John Arne and Bujnicki, Janusz and Jeronimo, Carmen and Almeida, Raquel and Neagu, Monica and Costache, Marieta and Banković, Jasna and Banović Đeri, Bojana and Kyselovic, Jan and Valor, Luis Miguel and Selbert, Stefan and Pir, Pinar and Demircan, Turan and Cowling, Victoria and Schaefer, Matthias and Rossmanith, Walter and Lafontaine, Denis and David, Alexandre and Carre, Clement and Lyko, Frank and Schaffrath, Raffael and Schwartz, Schraga and Verdel, Andre and Klungland, Arne and Purta, Elzbieta and Timotijević, Gordana and Cardona, Fernando and Davalos, Alberto and Ballana, Ester and O'Carroll, Donal and Ule, Jernej and Fray, Rupert", year = "2018", abstract = "The genetic alphabet consists of the four letters: C, A, G, and T in DNA and C,A,G, and U in RNA. Triplets of these four letters jointly encode 20 different amino acids out of which proteins of all organisms are built. This system is universal and is found in all kingdoms of life. However, bases in DNA and RNA can be chemically modified. In DNA, around 10 different modifications are known, and those have been studied intensively over the past 20years. Scientific studies on DNA modifications and proteins that recognize them gave rise to the large field of epigenetic and epigenomic research. The outcome of this intense research field is the discovery that development, ageing, and stem-cell dependent regeneration but also several diseases including cancer are largely controlled by the epigenetic state of cells. Consequently, this research has already led to the first FDA approved drugs that exploit the gained knowledge to combat disease. In recent years, the similar to 150 modifications found in RNA have come to the focus of intense research. Here we provide a perspective on necessary and expected developments in the fast expanding area of RNA modifications, termed epitranscriptomics.", publisher = "Taylor & Francis Inc, Philadelphia", journal = "RNA Biology", title = "Positioning Europe for the EPITRANSCRIPTOMICS challenge", pages = "831-829", number = "6", volume = "15", doi = "10.1080/15476286.2018.1460996" }
Jantsch, M. F., Quattrone, A., O'Connell, M., Helm, M., Frye, M., Macias-Gonzales, M., Ohman, M., Ameres, S., Willems, L., Fuks, F., Oulas, A., Vanacova, S., Nielsen, H., Bousquet-Antonelli, C., Motorin, Y., Roignant, J., Balatsos, N., Dinnyes, A., Baranov, P., Kelly, V., Lamm, A., Rechavi, G., Pelizzola, M., Liepins, J., Kholodnyuk, I. H., Zammit, V., Ayers, D., Drablos, F., Dahl, J. A., Bujnicki, J., Jeronimo, C., Almeida, R., Neagu, M., Costache, M., Banković, J., Banović Đeri, B., Kyselovic, J., Valor, L. M., Selbert, S., Pir, P., Demircan, T., Cowling, V., Schaefer, M., Rossmanith, W., Lafontaine, D., David, A., Carre, C., Lyko, F., Schaffrath, R., Schwartz, S., Verdel, A., Klungland, A., Purta, E., Timotijević, G., Cardona, F., Davalos, A., Ballana, E., O'Carroll, D., Ule, J.,& Fray, R.. (2018). Positioning Europe for the EPITRANSCRIPTOMICS challenge. in RNA Biology Taylor & Francis Inc, Philadelphia., 15(6), 829-831. https://doi.org/10.1080/15476286.2018.1460996
Jantsch MF, Quattrone A, O'Connell M, Helm M, Frye M, Macias-Gonzales M, Ohman M, Ameres S, Willems L, Fuks F, Oulas A, Vanacova S, Nielsen H, Bousquet-Antonelli C, Motorin Y, Roignant J, Balatsos N, Dinnyes A, Baranov P, Kelly V, Lamm A, Rechavi G, Pelizzola M, Liepins J, Kholodnyuk IH, Zammit V, Ayers D, Drablos F, Dahl JA, Bujnicki J, Jeronimo C, Almeida R, Neagu M, Costache M, Banković J, Banović Đeri B, Kyselovic J, Valor LM, Selbert S, Pir P, Demircan T, Cowling V, Schaefer M, Rossmanith W, Lafontaine D, David A, Carre C, Lyko F, Schaffrath R, Schwartz S, Verdel A, Klungland A, Purta E, Timotijević G, Cardona F, Davalos A, Ballana E, O'Carroll D, Ule J, Fray R. Positioning Europe for the EPITRANSCRIPTOMICS challenge. in RNA Biology. 2018;15(6):829-831. doi:10.1080/15476286.2018.1460996 .
Jantsch, Michael F., Quattrone, Alessandro, O'Connell, Mary, Helm, Mark, Frye, Michaela, Macias-Gonzales, Manuel, Ohman, Marie, Ameres, Stefan, Willems, Luc, Fuks, Francois, Oulas, Anastasis, Vanacova, Stepanka, Nielsen, Henrik, Bousquet-Antonelli, Cecile, Motorin, Yuri, Roignant, Jean-Yves, Balatsos, Nikolaos, Dinnyes, Andras, Baranov, Pavel, Kelly, Vincent, Lamm, Ayelet, Rechavi, Gideon, Pelizzola, Mattia, Liepins, Janis, Kholodnyuk, Irina Holodnuka, Zammit, Vanessa, Ayers, Duncan, Drablos, Finn, Dahl, John Arne, Bujnicki, Janusz, Jeronimo, Carmen, Almeida, Raquel, Neagu, Monica, Costache, Marieta, Banković, Jasna, Banović Đeri, Bojana, Kyselovic, Jan, Valor, Luis Miguel, Selbert, Stefan, Pir, Pinar, Demircan, Turan, Cowling, Victoria, Schaefer, Matthias, Rossmanith, Walter, Lafontaine, Denis, David, Alexandre, Carre, Clement, Lyko, Frank, Schaffrath, Raffael, Schwartz, Schraga, Verdel, Andre, Klungland, Arne, Purta, Elzbieta, Timotijević, Gordana, Cardona, Fernando, Davalos, Alberto, Ballana, Ester, O'Carroll, Donal, Ule, Jernej, Fray, Rupert, "Positioning Europe for the EPITRANSCRIPTOMICS challenge" in RNA Biology, 15, no. 6 (2018):829-831, https://doi.org/10.1080/15476286.2018.1460996 . .