Optimization of ultrasound-assisted extraction of total polyphenolic compounds from Juglans nigra L. leaves
Аутори
Gavrilović, MarijanaRajković, Katarina M.
Simić, Valentina
Jeremić, Sanja
Mirković, Snjezana
Jevtić, Aleksandra S.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The ultrasound-assisted extraction of Juglans nigra L. leaves was optimized with respect to total phenolic content (TP) of the extracts by varying the concentration of aqueous ethanol solution (E) and different solvent-to-solid ratio (S). The influence and optimum of the operating parameters (E and S) was examined using response surface methodology (RSM). The statistical criteria indicated the adequacy, reliability and precision of the developed RSM model. RSM showed that maximum extraction yield of TP 28.59 mg g(-1) of draw plant was achieved at the optimal values of 50% E and 20 kg kg(-1) S. Using the modelled optimized conditions, the detected relative difference between the predicted and the experimental yield was +/- 2.3 %. The determined TP content in the extracts varied from 12.54 to 29.26 mg GAE g(-1) of dry plant indicated that J. nigra is a valuable source of phenolic substances. The extracts of J. nigra leaves obtained under optimal conditions showed good antioxidant activit...y (IC50 = = 18.91 +/- 0.03 mu g cm(-3)) which was determined by the scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radical. The optimization of the TP extraction process is the important step in improving techno-economics of the potential commercial preparation of J. nigra extracts, as natural source of antioxidants.
Кључне речи:
response surface methodology / polyphenols / black walnutИзвор:
Journal of the Serbian Chemical Society, 2018, 83, 11, 1273-1284Издавач:
- Srpsko hemijsko društvo, Beograd
Финансирање / пројекти:
- Значај доказивања раних лабораторијских биомаркера за исход инвазивних гљивичних инфекција код нас (RS-MESTD-Basic Research (BR or ON)-175034)
DOI: 10.2298/JSC180321069G
ISSN: 0352-5139
WoS: 000452167500007
Scopus: 2-s2.0-85058976921
Институција/група
Institut za molekularnu genetiku i genetičko inženjerstvoTY - JOUR AU - Gavrilović, Marijana AU - Rajković, Katarina M. AU - Simić, Valentina AU - Jeremić, Sanja AU - Mirković, Snjezana AU - Jevtić, Aleksandra S. PY - 2018 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/1128 AB - The ultrasound-assisted extraction of Juglans nigra L. leaves was optimized with respect to total phenolic content (TP) of the extracts by varying the concentration of aqueous ethanol solution (E) and different solvent-to-solid ratio (S). The influence and optimum of the operating parameters (E and S) was examined using response surface methodology (RSM). The statistical criteria indicated the adequacy, reliability and precision of the developed RSM model. RSM showed that maximum extraction yield of TP 28.59 mg g(-1) of draw plant was achieved at the optimal values of 50% E and 20 kg kg(-1) S. Using the modelled optimized conditions, the detected relative difference between the predicted and the experimental yield was +/- 2.3 %. The determined TP content in the extracts varied from 12.54 to 29.26 mg GAE g(-1) of dry plant indicated that J. nigra is a valuable source of phenolic substances. The extracts of J. nigra leaves obtained under optimal conditions showed good antioxidant activity (IC50 = = 18.91 +/- 0.03 mu g cm(-3)) which was determined by the scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radical. The optimization of the TP extraction process is the important step in improving techno-economics of the potential commercial preparation of J. nigra extracts, as natural source of antioxidants. PB - Srpsko hemijsko društvo, Beograd T2 - Journal of the Serbian Chemical Society T1 - Optimization of ultrasound-assisted extraction of total polyphenolic compounds from Juglans nigra L. leaves EP - 1284 IS - 11 SP - 1273 VL - 83 DO - 10.2298/JSC180321069G ER -
@article{ author = "Gavrilović, Marijana and Rajković, Katarina M. and Simić, Valentina and Jeremić, Sanja and Mirković, Snjezana and Jevtić, Aleksandra S.", year = "2018", abstract = "The ultrasound-assisted extraction of Juglans nigra L. leaves was optimized with respect to total phenolic content (TP) of the extracts by varying the concentration of aqueous ethanol solution (E) and different solvent-to-solid ratio (S). The influence and optimum of the operating parameters (E and S) was examined using response surface methodology (RSM). The statistical criteria indicated the adequacy, reliability and precision of the developed RSM model. RSM showed that maximum extraction yield of TP 28.59 mg g(-1) of draw plant was achieved at the optimal values of 50% E and 20 kg kg(-1) S. Using the modelled optimized conditions, the detected relative difference between the predicted and the experimental yield was +/- 2.3 %. The determined TP content in the extracts varied from 12.54 to 29.26 mg GAE g(-1) of dry plant indicated that J. nigra is a valuable source of phenolic substances. The extracts of J. nigra leaves obtained under optimal conditions showed good antioxidant activity (IC50 = = 18.91 +/- 0.03 mu g cm(-3)) which was determined by the scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radical. The optimization of the TP extraction process is the important step in improving techno-economics of the potential commercial preparation of J. nigra extracts, as natural source of antioxidants.", publisher = "Srpsko hemijsko društvo, Beograd", journal = "Journal of the Serbian Chemical Society", title = "Optimization of ultrasound-assisted extraction of total polyphenolic compounds from Juglans nigra L. leaves", pages = "1284-1273", number = "11", volume = "83", doi = "10.2298/JSC180321069G" }
Gavrilović, M., Rajković, K. M., Simić, V., Jeremić, S., Mirković, S.,& Jevtić, A. S.. (2018). Optimization of ultrasound-assisted extraction of total polyphenolic compounds from Juglans nigra L. leaves. in Journal of the Serbian Chemical Society Srpsko hemijsko društvo, Beograd., 83(11), 1273-1284. https://doi.org/10.2298/JSC180321069G
Gavrilović M, Rajković KM, Simić V, Jeremić S, Mirković S, Jevtić AS. Optimization of ultrasound-assisted extraction of total polyphenolic compounds from Juglans nigra L. leaves. in Journal of the Serbian Chemical Society. 2018;83(11):1273-1284. doi:10.2298/JSC180321069G .
Gavrilović, Marijana, Rajković, Katarina M., Simić, Valentina, Jeremić, Sanja, Mirković, Snjezana, Jevtić, Aleksandra S., "Optimization of ultrasound-assisted extraction of total polyphenolic compounds from Juglans nigra L. leaves" in Journal of the Serbian Chemical Society, 83, no. 11 (2018):1273-1284, https://doi.org/10.2298/JSC180321069G . .