High-resolution human/goat comparative map of the goat polled/intersex syndrome (PIS): The human homologue is contained in a human YAC from HSA3q23
1999
Аутори
Vaiman, DSchibler, L
Oustry-Vaiman, A
Pailhoux, E
Goldammer, T
Stevanović, Milena
Furet, JP
Schwerin, M
Cotinot, C
Fellous, M
Cribiu, EP
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The genetic and cytogenetic map around the chromosome 1 region shown to be linked with polledness and intersexuality (PIS) in the domestic goat (Capra hircus) was refined. For this purpose, a goat BAC library was systematically screened with primers from human coding sequences, scraped chromosome 1 DNA, bovine microsatellites from the region, and BAC ends. All the BACs (n = 30) were mapped by fluorescence in. situ hybridization (FISH) on goat chromosome 1q41-q45. The genetic mapping of 30 new goat polymorphic markers, isolated from these BACs, made it possible to reduce the PIS interval to a region of less than 1 cM on goat chromosome 1q43. The PIS locus is now located between the two genes ATP1B and COP, which both map to 3q23 in humans. Genetic, cytogenetic, and comparative data suggest that the PIS region is now probably circumscribed to an similar to 1-Mb DNA segment for which construction of a BAC contig is in progress. In addition, a human YAC contig encompassing the blepharophim...osis-ptosis-epicanthus-inversus region was mapped by FISH to goat chromosome 1q43. This human disease, mapped to HSA 3q23 and affecting the development and maintenance of ovarian function, could be a potential candidate for goat PIS.
Извор:
Genomics, 1999, 56, 1, 31-39Издавач:
- Academic Press Inc Elsevier Science, San Diego
DOI: 10.1006/geno.1998.5691
ISSN: 0888-7543
PubMed: 10036183
WoS: 000078850100004
Scopus: 2-s2.0-0033557826
Институција/група
Institut za molekularnu genetiku i genetičko inženjerstvoTY - JOUR AU - Vaiman, D AU - Schibler, L AU - Oustry-Vaiman, A AU - Pailhoux, E AU - Goldammer, T AU - Stevanović, Milena AU - Furet, JP AU - Schwerin, M AU - Cotinot, C AU - Fellous, M AU - Cribiu, EP PY - 1999 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/120 AB - The genetic and cytogenetic map around the chromosome 1 region shown to be linked with polledness and intersexuality (PIS) in the domestic goat (Capra hircus) was refined. For this purpose, a goat BAC library was systematically screened with primers from human coding sequences, scraped chromosome 1 DNA, bovine microsatellites from the region, and BAC ends. All the BACs (n = 30) were mapped by fluorescence in. situ hybridization (FISH) on goat chromosome 1q41-q45. The genetic mapping of 30 new goat polymorphic markers, isolated from these BACs, made it possible to reduce the PIS interval to a region of less than 1 cM on goat chromosome 1q43. The PIS locus is now located between the two genes ATP1B and COP, which both map to 3q23 in humans. Genetic, cytogenetic, and comparative data suggest that the PIS region is now probably circumscribed to an similar to 1-Mb DNA segment for which construction of a BAC contig is in progress. In addition, a human YAC contig encompassing the blepharophimosis-ptosis-epicanthus-inversus region was mapped by FISH to goat chromosome 1q43. This human disease, mapped to HSA 3q23 and affecting the development and maintenance of ovarian function, could be a potential candidate for goat PIS. PB - Academic Press Inc Elsevier Science, San Diego T2 - Genomics T1 - High-resolution human/goat comparative map of the goat polled/intersex syndrome (PIS): The human homologue is contained in a human YAC from HSA3q23 EP - 39 IS - 1 SP - 31 VL - 56 DO - 10.1006/geno.1998.5691 ER -
@article{ author = "Vaiman, D and Schibler, L and Oustry-Vaiman, A and Pailhoux, E and Goldammer, T and Stevanović, Milena and Furet, JP and Schwerin, M and Cotinot, C and Fellous, M and Cribiu, EP", year = "1999", abstract = "The genetic and cytogenetic map around the chromosome 1 region shown to be linked with polledness and intersexuality (PIS) in the domestic goat (Capra hircus) was refined. For this purpose, a goat BAC library was systematically screened with primers from human coding sequences, scraped chromosome 1 DNA, bovine microsatellites from the region, and BAC ends. All the BACs (n = 30) were mapped by fluorescence in. situ hybridization (FISH) on goat chromosome 1q41-q45. The genetic mapping of 30 new goat polymorphic markers, isolated from these BACs, made it possible to reduce the PIS interval to a region of less than 1 cM on goat chromosome 1q43. The PIS locus is now located between the two genes ATP1B and COP, which both map to 3q23 in humans. Genetic, cytogenetic, and comparative data suggest that the PIS region is now probably circumscribed to an similar to 1-Mb DNA segment for which construction of a BAC contig is in progress. In addition, a human YAC contig encompassing the blepharophimosis-ptosis-epicanthus-inversus region was mapped by FISH to goat chromosome 1q43. This human disease, mapped to HSA 3q23 and affecting the development and maintenance of ovarian function, could be a potential candidate for goat PIS.", publisher = "Academic Press Inc Elsevier Science, San Diego", journal = "Genomics", title = "High-resolution human/goat comparative map of the goat polled/intersex syndrome (PIS): The human homologue is contained in a human YAC from HSA3q23", pages = "39-31", number = "1", volume = "56", doi = "10.1006/geno.1998.5691" }
Vaiman, D., Schibler, L., Oustry-Vaiman, A., Pailhoux, E., Goldammer, T., Stevanović, M., Furet, J., Schwerin, M., Cotinot, C., Fellous, M.,& Cribiu, E.. (1999). High-resolution human/goat comparative map of the goat polled/intersex syndrome (PIS): The human homologue is contained in a human YAC from HSA3q23. in Genomics Academic Press Inc Elsevier Science, San Diego., 56(1), 31-39. https://doi.org/10.1006/geno.1998.5691
Vaiman D, Schibler L, Oustry-Vaiman A, Pailhoux E, Goldammer T, Stevanović M, Furet J, Schwerin M, Cotinot C, Fellous M, Cribiu E. High-resolution human/goat comparative map of the goat polled/intersex syndrome (PIS): The human homologue is contained in a human YAC from HSA3q23. in Genomics. 1999;56(1):31-39. doi:10.1006/geno.1998.5691 .
Vaiman, D, Schibler, L, Oustry-Vaiman, A, Pailhoux, E, Goldammer, T, Stevanović, Milena, Furet, JP, Schwerin, M, Cotinot, C, Fellous, M, Cribiu, EP, "High-resolution human/goat comparative map of the goat polled/intersex syndrome (PIS): The human homologue is contained in a human YAC from HSA3q23" in Genomics, 56, no. 1 (1999):31-39, https://doi.org/10.1006/geno.1998.5691 . .