Complete mitogenome data for the Serbian population: the contribution to high-quality forensic databases
Samo za registrovane korisnike
2020
Autori
Davidović, SlobodanMalyarchuk, Boris
Grzybowski, Tomasz
Aleksić, Jelena M.
Derenko, Miroslava
Litvinov, Andrey
Rogalla-Ladniak, Urszula
Stevanović, Milena
Kovačević Grujičić, Nataša
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Mitochondrial genome (mtDNA) is a valuable resource in resolving various human forensic casework. The usage of variability of complete mtDNA genomes increases their discriminatory power to the maximum and enables ultimate resolution of distinct maternal lineages. However, their wider employment in forensic casework is nowadays limited by the lack of appropriate reference database. In order to fill in the gap in the reference data, which, considering Slavic-speaking populations, currently comprises only mitogenomes of East and West Slavs, we present mitogenome data for 226 Serbians, representatives of South Slavs from the Balkan Peninsula. We found 143 (sub)haplogroups among which West Eurasian ones were dominant. The percentage of unique haplotypes was 85%, and the random match probability was as low as 0.53%. We support previous findings on both high levels of genetic diversity in the Serbian population and patterns of genetic differentiation among this and ten studied European popula...tions. However, our high-resolution data supported more pronounced genetic differentiation among Serbians and two Slavic populations (Russians and Poles) as well as expansion of the Serbian population after the Last Glacial Maximum and during the Migration period (fourth to ninth century A.D.), as inferred from the Bayesian skyline analysis. Phylogenetic analysis of haplotypes found in Serbians contributed towards the improvement of the worldwide mtDNA phylogeny, which is essential for the interpretation of the mtDNA casework.
Ključne reči:
Serbian population / Molecular phylogeography / Demographic changes / Complete mitogenomesIzvor:
International Journal of Legal Medicine, 2020, 134, 5, 1581-1590Izdavač:
- New York : Springer
Finansiranje / projekti:
- Russian Foundation for Basic Research [14-04-00131, 16-34-00014]
- Etnogeneza Srba u srednjem veku: Uporedna analiza istorijsko-kulturnog nasleđa, genetičkog materijala i predmeta materijalne kulture sa aspekta analitičke hemije (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-47025)
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200042 (Univerzitet u Beogradu, Institut za molekularnu genetiku i genetičko inženjerstvo) (RS-MESTD-inst-2020-200042)
DOI: 10.1007/s00414-020-02324-x
ISSN: 0937-9827
PubMed: 32504149
WoS: 000538242000001
Scopus: 2-s2.0-85086108468
Institucija/grupa
Institut za molekularnu genetiku i genetičko inženjerstvoTY - JOUR AU - Davidović, Slobodan AU - Malyarchuk, Boris AU - Grzybowski, Tomasz AU - Aleksić, Jelena M. AU - Derenko, Miroslava AU - Litvinov, Andrey AU - Rogalla-Ladniak, Urszula AU - Stevanović, Milena AU - Kovačević Grujičić, Nataša PY - 2020 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/1324 AB - Mitochondrial genome (mtDNA) is a valuable resource in resolving various human forensic casework. The usage of variability of complete mtDNA genomes increases their discriminatory power to the maximum and enables ultimate resolution of distinct maternal lineages. However, their wider employment in forensic casework is nowadays limited by the lack of appropriate reference database. In order to fill in the gap in the reference data, which, considering Slavic-speaking populations, currently comprises only mitogenomes of East and West Slavs, we present mitogenome data for 226 Serbians, representatives of South Slavs from the Balkan Peninsula. We found 143 (sub)haplogroups among which West Eurasian ones were dominant. The percentage of unique haplotypes was 85%, and the random match probability was as low as 0.53%. We support previous findings on both high levels of genetic diversity in the Serbian population and patterns of genetic differentiation among this and ten studied European populations. However, our high-resolution data supported more pronounced genetic differentiation among Serbians and two Slavic populations (Russians and Poles) as well as expansion of the Serbian population after the Last Glacial Maximum and during the Migration period (fourth to ninth century A.D.), as inferred from the Bayesian skyline analysis. Phylogenetic analysis of haplotypes found in Serbians contributed towards the improvement of the worldwide mtDNA phylogeny, which is essential for the interpretation of the mtDNA casework. PB - New York : Springer T2 - International Journal of Legal Medicine T1 - Complete mitogenome data for the Serbian population: the contribution to high-quality forensic databases EP - 1590 IS - 5 SP - 1581 VL - 134 DO - 10.1007/s00414-020-02324-x ER -
@article{ author = "Davidović, Slobodan and Malyarchuk, Boris and Grzybowski, Tomasz and Aleksić, Jelena M. and Derenko, Miroslava and Litvinov, Andrey and Rogalla-Ladniak, Urszula and Stevanović, Milena and Kovačević Grujičić, Nataša", year = "2020", abstract = "Mitochondrial genome (mtDNA) is a valuable resource in resolving various human forensic casework. The usage of variability of complete mtDNA genomes increases their discriminatory power to the maximum and enables ultimate resolution of distinct maternal lineages. However, their wider employment in forensic casework is nowadays limited by the lack of appropriate reference database. In order to fill in the gap in the reference data, which, considering Slavic-speaking populations, currently comprises only mitogenomes of East and West Slavs, we present mitogenome data for 226 Serbians, representatives of South Slavs from the Balkan Peninsula. We found 143 (sub)haplogroups among which West Eurasian ones were dominant. The percentage of unique haplotypes was 85%, and the random match probability was as low as 0.53%. We support previous findings on both high levels of genetic diversity in the Serbian population and patterns of genetic differentiation among this and ten studied European populations. However, our high-resolution data supported more pronounced genetic differentiation among Serbians and two Slavic populations (Russians and Poles) as well as expansion of the Serbian population after the Last Glacial Maximum and during the Migration period (fourth to ninth century A.D.), as inferred from the Bayesian skyline analysis. Phylogenetic analysis of haplotypes found in Serbians contributed towards the improvement of the worldwide mtDNA phylogeny, which is essential for the interpretation of the mtDNA casework.", publisher = "New York : Springer", journal = "International Journal of Legal Medicine", title = "Complete mitogenome data for the Serbian population: the contribution to high-quality forensic databases", pages = "1590-1581", number = "5", volume = "134", doi = "10.1007/s00414-020-02324-x" }
Davidović, S., Malyarchuk, B., Grzybowski, T., Aleksić, J. M., Derenko, M., Litvinov, A., Rogalla-Ladniak, U., Stevanović, M.,& Kovačević Grujičić, N.. (2020). Complete mitogenome data for the Serbian population: the contribution to high-quality forensic databases. in International Journal of Legal Medicine New York : Springer., 134(5), 1581-1590. https://doi.org/10.1007/s00414-020-02324-x
Davidović S, Malyarchuk B, Grzybowski T, Aleksić JM, Derenko M, Litvinov A, Rogalla-Ladniak U, Stevanović M, Kovačević Grujičić N. Complete mitogenome data for the Serbian population: the contribution to high-quality forensic databases. in International Journal of Legal Medicine. 2020;134(5):1581-1590. doi:10.1007/s00414-020-02324-x .
Davidović, Slobodan, Malyarchuk, Boris, Grzybowski, Tomasz, Aleksić, Jelena M., Derenko, Miroslava, Litvinov, Andrey, Rogalla-Ladniak, Urszula, Stevanović, Milena, Kovačević Grujičić, Nataša, "Complete mitogenome data for the Serbian population: the contribution to high-quality forensic databases" in International Journal of Legal Medicine, 134, no. 5 (2020):1581-1590, https://doi.org/10.1007/s00414-020-02324-x . .