First whole-genome analysis of the novel coronavirus (SARS-CoV-2) obtained from COVID-19 patients from five districts in Western Serbia
Authors
Vidanović, DejanTesović, Bojana
Volkening, Jeremy D.
Afonso, Claudio L.
Quick, Joshua
Sekler, Milanko
Knezević, Aleksandra
Janković, Marko
Jovanović, Tanja
Petrović, Tamas
Banović Đeri, Bojana
Article (Published version)
Metadata
Show full item recordAbstract
This study was endeavoured to contribute in furthering our understanding of the molecular epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by sequencing and analysing the first full-length genome sequences obtained from 48 coronavirus disease-2019 (COVID-19) patients in five districts in Western Serbia in the period April 2020-July 2020. SARS-CoV-2 sequences in Western Serbia distinguished from the Wuhan sequence in 128 SNPs in total. The phylogenetic structure of local SARS-CoV-2 isolates suggested the existence of at least four distinct groups of SARS-CoV-2 strains in Western Serbia. The first group is the most similar to the strain from Italy. These isolates included two 20A sequences and 15-30 20B sequences that displayed a newly occurring set of four conjoined mutations. The second group is the most similar to the strain from France, carrying two mutations and belonged to 20A clade. The third group is the most similar to the strain from Switzerland carr...ying four co-occurring mutations and belonging to 20B clade. The fourth group is the most similar to another strain from France, displaying one mutation that gave rise to a single local isolate that belonged to 20A clade.
Keywords:
whole-genome sequencing / Serbia / SARS-CoV-2 / COVID-19 / CoronavirusSource:
Epidemiology and Infection, 2021, 149Publisher:
- Cambridge Univ Press, New York
Funding / projects:
- Government of Republic of Serbia [53-3455/2020-3]
- Veterinary Specialized Institute Kraljevo
DOI: 10.1017/S095026882100220X
ISSN: 0950-2688
WoS: 000724739000001
Scopus: 2-s2.0-85119173781
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Institution/Community
Institut za molekularnu genetiku i genetičko inženjerstvoTY - JOUR AU - Vidanović, Dejan AU - Tesović, Bojana AU - Volkening, Jeremy D. AU - Afonso, Claudio L. AU - Quick, Joshua AU - Sekler, Milanko AU - Knezević, Aleksandra AU - Janković, Marko AU - Jovanović, Tanja AU - Petrović, Tamas AU - Banović Đeri, Bojana PY - 2021 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/1453 AB - This study was endeavoured to contribute in furthering our understanding of the molecular epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by sequencing and analysing the first full-length genome sequences obtained from 48 coronavirus disease-2019 (COVID-19) patients in five districts in Western Serbia in the period April 2020-July 2020. SARS-CoV-2 sequences in Western Serbia distinguished from the Wuhan sequence in 128 SNPs in total. The phylogenetic structure of local SARS-CoV-2 isolates suggested the existence of at least four distinct groups of SARS-CoV-2 strains in Western Serbia. The first group is the most similar to the strain from Italy. These isolates included two 20A sequences and 15-30 20B sequences that displayed a newly occurring set of four conjoined mutations. The second group is the most similar to the strain from France, carrying two mutations and belonged to 20A clade. The third group is the most similar to the strain from Switzerland carrying four co-occurring mutations and belonging to 20B clade. The fourth group is the most similar to another strain from France, displaying one mutation that gave rise to a single local isolate that belonged to 20A clade. PB - Cambridge Univ Press, New York T2 - Epidemiology and Infection T1 - First whole-genome analysis of the novel coronavirus (SARS-CoV-2) obtained from COVID-19 patients from five districts in Western Serbia VL - 149 DO - 10.1017/S095026882100220X ER -
@article{ author = "Vidanović, Dejan and Tesović, Bojana and Volkening, Jeremy D. and Afonso, Claudio L. and Quick, Joshua and Sekler, Milanko and Knezević, Aleksandra and Janković, Marko and Jovanović, Tanja and Petrović, Tamas and Banović Đeri, Bojana", year = "2021", abstract = "This study was endeavoured to contribute in furthering our understanding of the molecular epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by sequencing and analysing the first full-length genome sequences obtained from 48 coronavirus disease-2019 (COVID-19) patients in five districts in Western Serbia in the period April 2020-July 2020. SARS-CoV-2 sequences in Western Serbia distinguished from the Wuhan sequence in 128 SNPs in total. The phylogenetic structure of local SARS-CoV-2 isolates suggested the existence of at least four distinct groups of SARS-CoV-2 strains in Western Serbia. The first group is the most similar to the strain from Italy. These isolates included two 20A sequences and 15-30 20B sequences that displayed a newly occurring set of four conjoined mutations. The second group is the most similar to the strain from France, carrying two mutations and belonged to 20A clade. The third group is the most similar to the strain from Switzerland carrying four co-occurring mutations and belonging to 20B clade. The fourth group is the most similar to another strain from France, displaying one mutation that gave rise to a single local isolate that belonged to 20A clade.", publisher = "Cambridge Univ Press, New York", journal = "Epidemiology and Infection", title = "First whole-genome analysis of the novel coronavirus (SARS-CoV-2) obtained from COVID-19 patients from five districts in Western Serbia", volume = "149", doi = "10.1017/S095026882100220X" }
Vidanović, D., Tesović, B., Volkening, J. D., Afonso, C. L., Quick, J., Sekler, M., Knezević, A., Janković, M., Jovanović, T., Petrović, T.,& Banović Đeri, B.. (2021). First whole-genome analysis of the novel coronavirus (SARS-CoV-2) obtained from COVID-19 patients from five districts in Western Serbia. in Epidemiology and Infection Cambridge Univ Press, New York., 149. https://doi.org/10.1017/S095026882100220X
Vidanović D, Tesović B, Volkening JD, Afonso CL, Quick J, Sekler M, Knezević A, Janković M, Jovanović T, Petrović T, Banović Đeri B. First whole-genome analysis of the novel coronavirus (SARS-CoV-2) obtained from COVID-19 patients from five districts in Western Serbia. in Epidemiology and Infection. 2021;149. doi:10.1017/S095026882100220X .
Vidanović, Dejan, Tesović, Bojana, Volkening, Jeremy D., Afonso, Claudio L., Quick, Joshua, Sekler, Milanko, Knezević, Aleksandra, Janković, Marko, Jovanović, Tanja, Petrović, Tamas, Banović Đeri, Bojana, "First whole-genome analysis of the novel coronavirus (SARS-CoV-2) obtained from COVID-19 patients from five districts in Western Serbia" in Epidemiology and Infection, 149 (2021), https://doi.org/10.1017/S095026882100220X . .