Consumption of walnuts suppresses the conversion of palmitic to palmitoleic acid and enhances omega-3 fatty acid metabolism in the heart of fructose-fed rats
Nema prikaza
Autori
Romić, S.Tepavčević, S.
Popović, T.
Zec, M.
Stojiljković, Mojca
Ćulafić, T.
Bošković, M.
Korićanac, G.
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Walnut consumption mostly has a positive implication for cardiovascular health. Walnut diet effects on the cardiac fatty acid (FA) metabolism of healthy rats and those with fructose diet-induced metabolic burden were analysed. Both walnuts and fructose increased CD36 transporter level and the nuclear content of some/all of Lipin 1/PPARα/PGC-1 complex partners, as well as cytosolic and nuclear FOXO1. However, fructose, independently of walnuts, increased the content of palmitic (PA), oleic, and vaccenic acid (VA), while in walnut-fed rats failed to increase palmitoleic acid (POA) level and the POA/PA ratio, as well as total MUFA content. In opposite, walnuts reduced the level of PA and VA and increased alpha-linolenic, eicosapentaenoic and docosapentaenoic acid level, regardless of fructose. In conclusion, both fructose and walnuts stimulated the uptake and oxidation of FA in the heart, but the walnuts, opposite to fructose, favourably altered cardiac FA profile in healthy and metabolic...ally compromised rats.
Ključne reči:
Walnut (Juglans regia) / heart / Fructose-rich diet / fatty acid metabolismIzvor:
International Journal of Food Sciences and Nutrition, 2022Izdavač:
- Taylor and Francis Ltd.
DOI: 10.1080/09637486.2022.2107186
ISSN: 0963-7486
WoS: 00083601010000
Scopus: 2-s2.0-85135304774
Institucija/grupa
Institut za molekularnu genetiku i genetičko inženjerstvoTY - JOUR AU - Romić, S. AU - Tepavčević, S. AU - Popović, T. AU - Zec, M. AU - Stojiljković, Mojca AU - Ćulafić, T. AU - Bošković, M. AU - Korićanac, G. PY - 2022 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/1541 AB - Walnut consumption mostly has a positive implication for cardiovascular health. Walnut diet effects on the cardiac fatty acid (FA) metabolism of healthy rats and those with fructose diet-induced metabolic burden were analysed. Both walnuts and fructose increased CD36 transporter level and the nuclear content of some/all of Lipin 1/PPARα/PGC-1 complex partners, as well as cytosolic and nuclear FOXO1. However, fructose, independently of walnuts, increased the content of palmitic (PA), oleic, and vaccenic acid (VA), while in walnut-fed rats failed to increase palmitoleic acid (POA) level and the POA/PA ratio, as well as total MUFA content. In opposite, walnuts reduced the level of PA and VA and increased alpha-linolenic, eicosapentaenoic and docosapentaenoic acid level, regardless of fructose. In conclusion, both fructose and walnuts stimulated the uptake and oxidation of FA in the heart, but the walnuts, opposite to fructose, favourably altered cardiac FA profile in healthy and metabolically compromised rats. PB - Taylor and Francis Ltd. T2 - International Journal of Food Sciences and Nutrition T1 - Consumption of walnuts suppresses the conversion of palmitic to palmitoleic acid and enhances omega-3 fatty acid metabolism in the heart of fructose-fed rats DO - 10.1080/09637486.2022.2107186 ER -
@article{ author = "Romić, S. and Tepavčević, S. and Popović, T. and Zec, M. and Stojiljković, Mojca and Ćulafić, T. and Bošković, M. and Korićanac, G.", year = "2022", abstract = "Walnut consumption mostly has a positive implication for cardiovascular health. Walnut diet effects on the cardiac fatty acid (FA) metabolism of healthy rats and those with fructose diet-induced metabolic burden were analysed. Both walnuts and fructose increased CD36 transporter level and the nuclear content of some/all of Lipin 1/PPARα/PGC-1 complex partners, as well as cytosolic and nuclear FOXO1. However, fructose, independently of walnuts, increased the content of palmitic (PA), oleic, and vaccenic acid (VA), while in walnut-fed rats failed to increase palmitoleic acid (POA) level and the POA/PA ratio, as well as total MUFA content. In opposite, walnuts reduced the level of PA and VA and increased alpha-linolenic, eicosapentaenoic and docosapentaenoic acid level, regardless of fructose. In conclusion, both fructose and walnuts stimulated the uptake and oxidation of FA in the heart, but the walnuts, opposite to fructose, favourably altered cardiac FA profile in healthy and metabolically compromised rats.", publisher = "Taylor and Francis Ltd.", journal = "International Journal of Food Sciences and Nutrition", title = "Consumption of walnuts suppresses the conversion of palmitic to palmitoleic acid and enhances omega-3 fatty acid metabolism in the heart of fructose-fed rats", doi = "10.1080/09637486.2022.2107186" }
Romić, S., Tepavčević, S., Popović, T., Zec, M., Stojiljković, M., Ćulafić, T., Bošković, M.,& Korićanac, G.. (2022). Consumption of walnuts suppresses the conversion of palmitic to palmitoleic acid and enhances omega-3 fatty acid metabolism in the heart of fructose-fed rats. in International Journal of Food Sciences and Nutrition Taylor and Francis Ltd... https://doi.org/10.1080/09637486.2022.2107186
Romić S, Tepavčević S, Popović T, Zec M, Stojiljković M, Ćulafić T, Bošković M, Korićanac G. Consumption of walnuts suppresses the conversion of palmitic to palmitoleic acid and enhances omega-3 fatty acid metabolism in the heart of fructose-fed rats. in International Journal of Food Sciences and Nutrition. 2022;. doi:10.1080/09637486.2022.2107186 .
Romić, S., Tepavčević, S., Popović, T., Zec, M., Stojiljković, Mojca, Ćulafić, T., Bošković, M., Korićanac, G., "Consumption of walnuts suppresses the conversion of palmitic to palmitoleic acid and enhances omega-3 fatty acid metabolism in the heart of fructose-fed rats" in International Journal of Food Sciences and Nutrition (2022), https://doi.org/10.1080/09637486.2022.2107186 . .