Hydrogel Scaffolds Based on Alginate, Gelatin, and 2-Hydroxyethyl Methacrylate for Tissue Regeneration
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Tomić, Simonida Lj.Vukomanović, Marija
Nikodinović-Runić, Jasmina
Babić, Marija M.
Vuković, Jovana S.
Jana, Sougata
Jana, Subrata
Book part (Published version)
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The design of bioactive scaffolding materials with favorable properties is paramount for successful application in biomedical engineering. Polymeric hydrogels attract significant attention as leading candidates for scaffold engineering due to their specific compositional and structural similarities to the natural extracellular matrix. The ability to control porosity, surface morphology, and size of hydrogel scaffolds has created new approaches to overcome various issues in tissue engineering such as vascularization, tissue architecture, and simultaneous multiple cells seeding. This review imparts an overview of hydrogel scaffolds based on synthetic and natural polymeric components (alginate, gelatin, and 2-hydroxyethyl methacrylate). We made hydrogel scaffolds with unique properties. Their in vitro and in vivo biological response, morphology, mechanical properties, porosity, hydrophilicity, and degradability were tested to find optimal patterns of tissue regeneration.
Keywords:
2-Hydroxyethyl methacrylate / Alginate / Gelatin / Hydrogel scaffolds / Tissue regenerationSource:
Marine Biomaterials: Therapeutic Potential, 2022, 173-204Publisher:
- Springer Nature
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Institut za molekularnu genetiku i genetičko inženjerstvoTY - CHAP AU - Tomić, Simonida Lj. AU - Vukomanović, Marija AU - Nikodinović-Runić, Jasmina AU - Babić, Marija M. AU - Vuković, Jovana S. AU - Jana, Sougata AU - Jana, Subrata PY - 2022 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/1655 AB - The design of bioactive scaffolding materials with favorable properties is paramount for successful application in biomedical engineering. Polymeric hydrogels attract significant attention as leading candidates for scaffold engineering due to their specific compositional and structural similarities to the natural extracellular matrix. The ability to control porosity, surface morphology, and size of hydrogel scaffolds has created new approaches to overcome various issues in tissue engineering such as vascularization, tissue architecture, and simultaneous multiple cells seeding. This review imparts an overview of hydrogel scaffolds based on synthetic and natural polymeric components (alginate, gelatin, and 2-hydroxyethyl methacrylate). We made hydrogel scaffolds with unique properties. Their in vitro and in vivo biological response, morphology, mechanical properties, porosity, hydrophilicity, and degradability were tested to find optimal patterns of tissue regeneration. PB - Springer Nature T2 - Marine Biomaterials: Therapeutic Potential T2 - Marine Biomaterials : Therapeutic Potential T1 - Hydrogel Scaffolds Based on Alginate, Gelatin, and 2-Hydroxyethyl Methacrylate for Tissue Regeneration EP - 204 SP - 173 DO - 10.1007/978-981-16-5374-2_6 ER -
@inbook{ author = "Tomić, Simonida Lj. and Vukomanović, Marija and Nikodinović-Runić, Jasmina and Babić, Marija M. and Vuković, Jovana S. and Jana, Sougata and Jana, Subrata", year = "2022", abstract = "The design of bioactive scaffolding materials with favorable properties is paramount for successful application in biomedical engineering. Polymeric hydrogels attract significant attention as leading candidates for scaffold engineering due to their specific compositional and structural similarities to the natural extracellular matrix. The ability to control porosity, surface morphology, and size of hydrogel scaffolds has created new approaches to overcome various issues in tissue engineering such as vascularization, tissue architecture, and simultaneous multiple cells seeding. This review imparts an overview of hydrogel scaffolds based on synthetic and natural polymeric components (alginate, gelatin, and 2-hydroxyethyl methacrylate). We made hydrogel scaffolds with unique properties. Their in vitro and in vivo biological response, morphology, mechanical properties, porosity, hydrophilicity, and degradability were tested to find optimal patterns of tissue regeneration.", publisher = "Springer Nature", journal = "Marine Biomaterials: Therapeutic Potential, Marine Biomaterials : Therapeutic Potential", booktitle = "Hydrogel Scaffolds Based on Alginate, Gelatin, and 2-Hydroxyethyl Methacrylate for Tissue Regeneration", pages = "204-173", doi = "10.1007/978-981-16-5374-2_6" }
Tomić, S. Lj., Vukomanović, M., Nikodinović-Runić, J., Babić, M. M., Vuković, J. S., Jana, S.,& Jana, S.. (2022). Hydrogel Scaffolds Based on Alginate, Gelatin, and 2-Hydroxyethyl Methacrylate for Tissue Regeneration. in Marine Biomaterials: Therapeutic Potential Springer Nature., 173-204. https://doi.org/10.1007/978-981-16-5374-2_6
Tomić SL, Vukomanović M, Nikodinović-Runić J, Babić MM, Vuković JS, Jana S, Jana S. Hydrogel Scaffolds Based on Alginate, Gelatin, and 2-Hydroxyethyl Methacrylate for Tissue Regeneration. in Marine Biomaterials: Therapeutic Potential. 2022;:173-204. doi:10.1007/978-981-16-5374-2_6 .
Tomić, Simonida Lj., Vukomanović, Marija, Nikodinović-Runić, Jasmina, Babić, Marija M., Vuković, Jovana S., Jana, Sougata, Jana, Subrata, "Hydrogel Scaffolds Based on Alginate, Gelatin, and 2-Hydroxyethyl Methacrylate for Tissue Regeneration" in Marine Biomaterials: Therapeutic Potential (2022):173-204, https://doi.org/10.1007/978-981-16-5374-2_6 . .