Prognostic potential of circulating miR-93-5p in patients with colorectal liver metastases
Authors
Despotović, JovanaBogdanović, Aleksandar
Dragičević, Sandra
Galun, Danijel
Krivokapić, Zoran
Nikolić, Aleksandra
Conference object (Published version)
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Show full item recordAbstract
Approximately half of colorectal cancer (CRC) patients will develop liver metastases
(CRLM) during the course of the disease. Even with the use of modern adjuvant systemic treatment,
almost two thirds of metastatic colorectal cancer (mCRC) patients will eventually develop recurrent
disease after curative-intent surgery, thus the new prognostic biomarkers are necessary. The expression
signatures of microRNAs (miRNAs), a class of non-coding RNAs, have been associated with the
diagnosis, prognosis, and therapeutic response in CRC. The expression pattern and prognostic potential of
miR-93-5p has been studied previously in CRC but not in mCRC. The aim of this study was to examine
the expression pattern and prognostic potential of tumoral and circulating miR-93-5p in patients with
CRLM.
Keywords:
metastatic colorectal cancer / colorectal cancer liver metastasis / microRNA / miR-93-5p / prognostic biomarkerSource:
European Association for Cancer Research, 2021Publisher:
- EACR 2021 Virtual Congress: Innovative Cancer Science
Funding / projects:
- Molekularna osnova odgovora na hemioradioterapiju u karcinomu rektuma, Strateški projekat Srpske akademije nauka i umetnosti, F-69, 2019-2022
Note:
- EACR 2021 Virtual Congress: Innovative Cancer Science. 09-12 June 2021
URI
https://imagine.imgge.bg.ac.rs/handle/123456789/1802https://www.eacr2021.org/ https://fightcolorectalcancer.org/blog/recap-rally-on-research-eao-crc/
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Institution/Community
Institut za molekularnu genetiku i genetičko inženjerstvoTY - CONF AU - Despotović, Jovana AU - Bogdanović, Aleksandar AU - Dragičević, Sandra AU - Galun, Danijel AU - Krivokapić, Zoran AU - Nikolić, Aleksandra PY - 2021 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/1802 UR - https://www.eacr2021.org/ https://fightcolorectalcancer.org/blog/recap-rally-on-research-eao-crc/ AB - Approximately half of colorectal cancer (CRC) patients will develop liver metastases (CRLM) during the course of the disease. Even with the use of modern adjuvant systemic treatment, almost two thirds of metastatic colorectal cancer (mCRC) patients will eventually develop recurrent disease after curative-intent surgery, thus the new prognostic biomarkers are necessary. The expression signatures of microRNAs (miRNAs), a class of non-coding RNAs, have been associated with the diagnosis, prognosis, and therapeutic response in CRC. The expression pattern and prognostic potential of miR-93-5p has been studied previously in CRC but not in mCRC. The aim of this study was to examine the expression pattern and prognostic potential of tumoral and circulating miR-93-5p in patients with CRLM. PB - EACR 2021 Virtual Congress: Innovative Cancer Science C3 - European Association for Cancer Research T1 - Prognostic potential of circulating miR-93-5p in patients with colorectal liver metastases UR - https://hdl.handle.net/21.15107/rcub_imagine_1802 ER -
@conference{ author = "Despotović, Jovana and Bogdanović, Aleksandar and Dragičević, Sandra and Galun, Danijel and Krivokapić, Zoran and Nikolić, Aleksandra", year = "2021", abstract = "Approximately half of colorectal cancer (CRC) patients will develop liver metastases (CRLM) during the course of the disease. Even with the use of modern adjuvant systemic treatment, almost two thirds of metastatic colorectal cancer (mCRC) patients will eventually develop recurrent disease after curative-intent surgery, thus the new prognostic biomarkers are necessary. The expression signatures of microRNAs (miRNAs), a class of non-coding RNAs, have been associated with the diagnosis, prognosis, and therapeutic response in CRC. The expression pattern and prognostic potential of miR-93-5p has been studied previously in CRC but not in mCRC. The aim of this study was to examine the expression pattern and prognostic potential of tumoral and circulating miR-93-5p in patients with CRLM.", publisher = "EACR 2021 Virtual Congress: Innovative Cancer Science", journal = "European Association for Cancer Research", title = "Prognostic potential of circulating miR-93-5p in patients with colorectal liver metastases", url = "https://hdl.handle.net/21.15107/rcub_imagine_1802" }
Despotović, J., Bogdanović, A., Dragičević, S., Galun, D., Krivokapić, Z.,& Nikolić, A.. (2021). Prognostic potential of circulating miR-93-5p in patients with colorectal liver metastases. in European Association for Cancer Research EACR 2021 Virtual Congress: Innovative Cancer Science.. https://hdl.handle.net/21.15107/rcub_imagine_1802
Despotović J, Bogdanović A, Dragičević S, Galun D, Krivokapić Z, Nikolić A. Prognostic potential of circulating miR-93-5p in patients with colorectal liver metastases. in European Association for Cancer Research. 2021;. https://hdl.handle.net/21.15107/rcub_imagine_1802 .
Despotović, Jovana, Bogdanović, Aleksandar, Dragičević, Sandra, Galun, Danijel, Krivokapić, Zoran, Nikolić, Aleksandra, "Prognostic potential of circulating miR-93-5p in patients with colorectal liver metastases" in European Association for Cancer Research (2021), https://hdl.handle.net/21.15107/rcub_imagine_1802 .