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Alternative splicing impacts microRNA regulation within coding regions
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate post-transcriptional
gene expression by binding to specific target sites. Approximately 95% of human multi-exon
genes can be spliced alternatively, which ...
Evaluation of variant calling tools for detection of SNVs in BRCA1 and BRCA2 genes in patients from the Institute of Oncology and Radiology of Serbia
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
Serbia has one of the world’s highest incidences and mortality rates of ovarian cancer.
Germline or somatic mutations in BRCA1 and BRCA2 genes, such as single nucleotide
variants (SNVs), indels, insertions, deletions, ...
Numerical and Biological Modeling Approach in the Analysis of the Cancer Viability and Apoptosis
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
Biomedicine is a multidisciplinary branch of science that requires a clear approach to the
study and analysis of various life processes necessary for a deeper understanding of
human health. This research focuses on the ...
CADDIE - An online knowledge base for network-based mechanism exploration and drug repurposing in oncolog
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
Drug repurposing is the use of previously developed and tested pharmaceutical agents in new
application cases and lately often used as a solution to the increasing drug development costs.
Cancers are extremely heterogeneous ...