Analysis of nucleotide sequence repeats in coronaviruses
Аутори
Kapunac, S.Malkov, S.
Pavlović Lažetić, G.
Stojanović, B.
Maljković, M.
Veljković, A.
Mitić, N.
Остала ауторства
Morić, IvanaĐorđević, Valentina
Конференцијски прилог (Објављена верзија)
,
© 2023 Institute of Molecular Genetics and Genetic Engineering, University of Belgrade
Метаподаци
Приказ свих података о документуАпстракт
Repeats in nucleotide sequences are connected with various genome characteristics.
RNA secondary structures are related to repeats at the primary structure level. Four
different types of nucleotide repeats may be identified: direct non-complementary,
direct complementary, inverse non-complementary and inverse complementary. Reverse
complementary tandem repeats, for example, may form hairpin secondary structures,
while reverse non-complementary may be recognized by proteins. On the other side,
direct complementary and/or non-complementary repeats may be reflected in protein
sequence repeats, if found in the same reading frame, within the protein-coding sequence.
Here we analyzed (determined and compared) all four types of nucleotide repeats in
referent sequences of SARS-CoV-1, SARS-CoV-2 and MERS-COV viruses. In addition
to the complete repeat set, we analyze different repeat subsets: repeats with the left
component within the 5’ end, repeats with the right component within t...he 3’ end, and
repeats with at least one component within the surface glycoprotein coding sequence.
We found significant differences in repeat sets corresponding to analyzed sequences
in all analyzed repeat sets. In this moment we can only speculate what are the real
consequences of the discovered differences
Кључне речи:
SARS-COV / MERS-COV / SARS-COV-2 / nucleotide repeatsИзвор:
4th Belgrade Bioinformatics Conference, 2023, 4, 80-80Издавач:
- Belgrade : Institute of molecular genetics and genetic engineering
Напомена:
- Book of abstract: 4th Belgrade Bioinformatics Conference, June 19-23, 2023
Колекције
Институција/група
Institut za molekularnu genetiku i genetičko inženjerstvoTY - CONF AU - Kapunac, S. AU - Malkov, S. AU - Pavlović Lažetić, G. AU - Stojanović, B. AU - Maljković, M. AU - Veljković, A. AU - Mitić, N. PY - 2023 UR - https://belbi.bg.ac.rs/ UR - https://imagine.imgge.bg.ac.rs/handle/123456789/2020 AB - Repeats in nucleotide sequences are connected with various genome characteristics. RNA secondary structures are related to repeats at the primary structure level. Four different types of nucleotide repeats may be identified: direct non-complementary, direct complementary, inverse non-complementary and inverse complementary. Reverse complementary tandem repeats, for example, may form hairpin secondary structures, while reverse non-complementary may be recognized by proteins. On the other side, direct complementary and/or non-complementary repeats may be reflected in protein sequence repeats, if found in the same reading frame, within the protein-coding sequence. Here we analyzed (determined and compared) all four types of nucleotide repeats in referent sequences of SARS-CoV-1, SARS-CoV-2 and MERS-COV viruses. In addition to the complete repeat set, we analyze different repeat subsets: repeats with the left component within the 5’ end, repeats with the right component within the 3’ end, and repeats with at least one component within the surface glycoprotein coding sequence. We found significant differences in repeat sets corresponding to analyzed sequences in all analyzed repeat sets. In this moment we can only speculate what are the real consequences of the discovered differences PB - Belgrade : Institute of molecular genetics and genetic engineering C3 - 4th Belgrade Bioinformatics Conference T1 - Analysis of nucleotide sequence repeats in coronaviruses EP - 80 SP - 80 VL - 4 UR - https://hdl.handle.net/21.15107/rcub_imagine_2020 ER -
@conference{ author = "Kapunac, S. and Malkov, S. and Pavlović Lažetić, G. and Stojanović, B. and Maljković, M. and Veljković, A. and Mitić, N.", year = "2023", abstract = "Repeats in nucleotide sequences are connected with various genome characteristics. RNA secondary structures are related to repeats at the primary structure level. Four different types of nucleotide repeats may be identified: direct non-complementary, direct complementary, inverse non-complementary and inverse complementary. Reverse complementary tandem repeats, for example, may form hairpin secondary structures, while reverse non-complementary may be recognized by proteins. On the other side, direct complementary and/or non-complementary repeats may be reflected in protein sequence repeats, if found in the same reading frame, within the protein-coding sequence. Here we analyzed (determined and compared) all four types of nucleotide repeats in referent sequences of SARS-CoV-1, SARS-CoV-2 and MERS-COV viruses. In addition to the complete repeat set, we analyze different repeat subsets: repeats with the left component within the 5’ end, repeats with the right component within the 3’ end, and repeats with at least one component within the surface glycoprotein coding sequence. We found significant differences in repeat sets corresponding to analyzed sequences in all analyzed repeat sets. In this moment we can only speculate what are the real consequences of the discovered differences", publisher = "Belgrade : Institute of molecular genetics and genetic engineering", journal = "4th Belgrade Bioinformatics Conference", title = "Analysis of nucleotide sequence repeats in coronaviruses", pages = "80-80", volume = "4", url = "https://hdl.handle.net/21.15107/rcub_imagine_2020" }
Kapunac, S., Malkov, S., Pavlović Lažetić, G., Stojanović, B., Maljković, M., Veljković, A.,& Mitić, N.. (2023). Analysis of nucleotide sequence repeats in coronaviruses. in 4th Belgrade Bioinformatics Conference Belgrade : Institute of molecular genetics and genetic engineering., 4, 80-80. https://hdl.handle.net/21.15107/rcub_imagine_2020
Kapunac S, Malkov S, Pavlović Lažetić G, Stojanović B, Maljković M, Veljković A, Mitić N. Analysis of nucleotide sequence repeats in coronaviruses. in 4th Belgrade Bioinformatics Conference. 2023;4:80-80. https://hdl.handle.net/21.15107/rcub_imagine_2020 .
Kapunac, S., Malkov, S., Pavlović Lažetić, G., Stojanović, B., Maljković, M., Veljković, A., Mitić, N., "Analysis of nucleotide sequence repeats in coronaviruses" in 4th Belgrade Bioinformatics Conference, 4 (2023):80-80, https://hdl.handle.net/21.15107/rcub_imagine_2020 .