STRENGTHENING THE NEXT-GENERATION SEQUENCING AND BIOINFORMATICS CAPACITIES IN THE REPUBLIC OF SERBIA
Apstrakt
Bioinformatics was established at the IMGGE
in collaboration with the Beijing Genomics Institute
(BGI) and with the support of the Government of
the Republic of Serbia. The Center was founded
with the aim of accelerating the implementation
of 4P medicine (Preventive, Predictive, Personalized,
and Participatory), in our country by using the
cutting-edge tools of molecular biology and information
technology. As such, the center is unique in
Serbia and the South East Europe region.
The state-of-the-art equipment existing at the
Center (DNBSEQ-G400 (BGI), NextSeq 550Dx,
2000 and MiSeq (Illumina) Sequencing Systems;
MinION (OxfordNanopore); MGISP-9600
High-throughput Automated Sample Preparation
System) offered a wide range of application: the
whole genome and whole exome sequencing, targeted
sequencing, transcriptome sequencing and
more. The analysis of data was facilitated by the
access to the National Platform for Artificial Intelligence providing space for secure data... storage, and
to a supercomputer (Nvidia), critical for processing
and analyzing Big Data.
Since its establishment more than 2000
SARS-CoV2 genomes were sequenced, 300 patient
samples undervent diagnostic work-up. Pilot project
for NIFTYPro screening was finished encompasing
58 pregnant women. First transcriptomes
and metagenomes were analyzed.
Further implementation of NGS methodology
in research and for diagnostics, and intensive
development of bioinformatics, by strengthening
the hardware and software capacities and the education
of the bioinformatics team, will lead us in
becoming driving force of the development of biomedicine
and biotechnology in Serbia, extending
collaboration beyond our borders.
Ključne reči:
NGS / 4P medicine / molecular diagnostics / NIPT / bioinformatics / genetic technologiesIzvor:
International Journal of Medical Genetics, 2023, 26, Supplement, 75-75Izdavač:
- Macedonian Academy of Sciences and Arts
Napomena:
- ABSTRACT BOOK: “Genetic Diseases from Diagnostics to Prevention and Therapy” October 05-14th Balkan Congress of Human Genetics & 9th Rare Disease SEE Meeting 2023; Skopje, October 05-07, 2023
Institucija/grupa
Institut za molekularnu genetiku i genetičko inženjerstvoTY - CONF AU - Divac Rankov, Aleksandra AU - Kušić-Tišma, Jelena AU - Đorđević, Valentina PY - 2023 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/2177 AB - Bioinformatics was established at the IMGGE in collaboration with the Beijing Genomics Institute (BGI) and with the support of the Government of the Republic of Serbia. The Center was founded with the aim of accelerating the implementation of 4P medicine (Preventive, Predictive, Personalized, and Participatory), in our country by using the cutting-edge tools of molecular biology and information technology. As such, the center is unique in Serbia and the South East Europe region. The state-of-the-art equipment existing at the Center (DNBSEQ-G400 (BGI), NextSeq 550Dx, 2000 and MiSeq (Illumina) Sequencing Systems; MinION (OxfordNanopore); MGISP-9600 High-throughput Automated Sample Preparation System) offered a wide range of application: the whole genome and whole exome sequencing, targeted sequencing, transcriptome sequencing and more. The analysis of data was facilitated by the access to the National Platform for Artificial Intelligence providing space for secure data storage, and to a supercomputer (Nvidia), critical for processing and analyzing Big Data. Since its establishment more than 2000 SARS-CoV2 genomes were sequenced, 300 patient samples undervent diagnostic work-up. Pilot project for NIFTYPro screening was finished encompasing 58 pregnant women. First transcriptomes and metagenomes were analyzed. Further implementation of NGS methodology in research and for diagnostics, and intensive development of bioinformatics, by strengthening the hardware and software capacities and the education of the bioinformatics team, will lead us in becoming driving force of the development of biomedicine and biotechnology in Serbia, extending collaboration beyond our borders. PB - Macedonian Academy of Sciences and Arts C3 - International Journal of Medical Genetics T1 - STRENGTHENING THE NEXT-GENERATION SEQUENCING AND BIOINFORMATICS CAPACITIES IN THE REPUBLIC OF SERBIA EP - 75 IS - Supplement SP - 75 VL - 26 UR - https://hdl.handle.net/21.15107/rcub_imagine_2177 ER -
@conference{ author = "Divac Rankov, Aleksandra and Kušić-Tišma, Jelena and Đorđević, Valentina", year = "2023", abstract = "Bioinformatics was established at the IMGGE in collaboration with the Beijing Genomics Institute (BGI) and with the support of the Government of the Republic of Serbia. The Center was founded with the aim of accelerating the implementation of 4P medicine (Preventive, Predictive, Personalized, and Participatory), in our country by using the cutting-edge tools of molecular biology and information technology. As such, the center is unique in Serbia and the South East Europe region. The state-of-the-art equipment existing at the Center (DNBSEQ-G400 (BGI), NextSeq 550Dx, 2000 and MiSeq (Illumina) Sequencing Systems; MinION (OxfordNanopore); MGISP-9600 High-throughput Automated Sample Preparation System) offered a wide range of application: the whole genome and whole exome sequencing, targeted sequencing, transcriptome sequencing and more. The analysis of data was facilitated by the access to the National Platform for Artificial Intelligence providing space for secure data storage, and to a supercomputer (Nvidia), critical for processing and analyzing Big Data. Since its establishment more than 2000 SARS-CoV2 genomes were sequenced, 300 patient samples undervent diagnostic work-up. Pilot project for NIFTYPro screening was finished encompasing 58 pregnant women. First transcriptomes and metagenomes were analyzed. Further implementation of NGS methodology in research and for diagnostics, and intensive development of bioinformatics, by strengthening the hardware and software capacities and the education of the bioinformatics team, will lead us in becoming driving force of the development of biomedicine and biotechnology in Serbia, extending collaboration beyond our borders.", publisher = "Macedonian Academy of Sciences and Arts", journal = "International Journal of Medical Genetics", title = "STRENGTHENING THE NEXT-GENERATION SEQUENCING AND BIOINFORMATICS CAPACITIES IN THE REPUBLIC OF SERBIA", pages = "75-75", number = "Supplement", volume = "26", url = "https://hdl.handle.net/21.15107/rcub_imagine_2177" }
Divac Rankov, A., Kušić-Tišma, J.,& Đorđević, V.. (2023). STRENGTHENING THE NEXT-GENERATION SEQUENCING AND BIOINFORMATICS CAPACITIES IN THE REPUBLIC OF SERBIA. in International Journal of Medical Genetics Macedonian Academy of Sciences and Arts., 26(Supplement), 75-75. https://hdl.handle.net/21.15107/rcub_imagine_2177
Divac Rankov A, Kušić-Tišma J, Đorđević V. STRENGTHENING THE NEXT-GENERATION SEQUENCING AND BIOINFORMATICS CAPACITIES IN THE REPUBLIC OF SERBIA. in International Journal of Medical Genetics. 2023;26(Supplement):75-75. https://hdl.handle.net/21.15107/rcub_imagine_2177 .
Divac Rankov, Aleksandra, Kušić-Tišma, Jelena, Đorđević, Valentina, "STRENGTHENING THE NEXT-GENERATION SEQUENCING AND BIOINFORMATICS CAPACITIES IN THE REPUBLIC OF SERBIA" in International Journal of Medical Genetics, 26, no. Supplement (2023):75-75, https://hdl.handle.net/21.15107/rcub_imagine_2177 .