Adaptable alginate-based microfibers for 3D in vitro cultures of cancer cells: an anticancer drug testing model
Аутори
Petrović, JelenaPańczyszyn, Elżbieta
Corazzari, Marco
Banićević, Ivana
Milivojević, Milena
Bojić, Luka
Stevanović, Milena
Dragoj, Miodrag
Pešić, Milica
Janković, Radmila
Obradović, Bojana
Stojkovska, Jasmina
Конференцијски прилог
Метаподаци
Приказ свих података о документуАпстракт
The slow advance in anticancer drug development can be attributed to the limitations of conventional models, predominantly monolayer cell (2D) cultures and animal models, which inadequately recapitulate the complex nature of human malignant tumors. Three-dimensional (3D) in vitro models are invaluable tools in drug screening; however, creating a universal model for all cancer types poses challenges due to the diverse nature of cancers. The aim of this work was to develop a single, versatile model using alginate microfibers to accommodate cultivation of various cancer cells.
Кључне речи:
preclinical drug screening / Hydrogel / 3D cancer model / hydroxyapatite / preclinical drug screeningИзвор:
Hemijska industrija (Chemical Industry), 2024, 78, 1S, 21-21Финансирање / пројекти:
- European Union’s Horizon 2020 research and innovation programme, grant no.952033
URI
https://www.ache-pub.org.rs/index.php/HemInd/article/view/1264https://imagine.imgge.bg.ac.rs/handle/123456789/2364
Колекције
Институција/група
Institut za molekularnu genetiku i genetičko inženjerstvoTY - CONF AU - Petrović, Jelena AU - Pańczyszyn, Elżbieta AU - Corazzari, Marco AU - Banićević, Ivana AU - Milivojević, Milena AU - Bojić, Luka AU - Stevanović, Milena AU - Dragoj, Miodrag AU - Pešić, Milica AU - Janković, Radmila AU - Obradović, Bojana AU - Stojkovska, Jasmina PY - 2024 UR - https://www.ache-pub.org.rs/index.php/HemInd/article/view/1264 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/2364 AB - The slow advance in anticancer drug development can be attributed to the limitations of conventional models, predominantly monolayer cell (2D) cultures and animal models, which inadequately recapitulate the complex nature of human malignant tumors. Three-dimensional (3D) in vitro models are invaluable tools in drug screening; however, creating a universal model for all cancer types poses challenges due to the diverse nature of cancers. The aim of this work was to develop a single, versatile model using alginate microfibers to accommodate cultivation of various cancer cells. C3 - Hemijska industrija (Chemical Industry) T1 - Adaptable alginate-based microfibers for 3D in vitro cultures of cancer cells: an anticancer drug testing model EP - 21 IS - 1S SP - 21 VL - 78 UR - https://hdl.handle.net/21.15107/rcub_imagine_2364 ER -
@conference{ author = "Petrović, Jelena and Pańczyszyn, Elżbieta and Corazzari, Marco and Banićević, Ivana and Milivojević, Milena and Bojić, Luka and Stevanović, Milena and Dragoj, Miodrag and Pešić, Milica and Janković, Radmila and Obradović, Bojana and Stojkovska, Jasmina", year = "2024", abstract = "The slow advance in anticancer drug development can be attributed to the limitations of conventional models, predominantly monolayer cell (2D) cultures and animal models, which inadequately recapitulate the complex nature of human malignant tumors. Three-dimensional (3D) in vitro models are invaluable tools in drug screening; however, creating a universal model for all cancer types poses challenges due to the diverse nature of cancers. The aim of this work was to develop a single, versatile model using alginate microfibers to accommodate cultivation of various cancer cells.", journal = "Hemijska industrija (Chemical Industry)", title = "Adaptable alginate-based microfibers for 3D in vitro cultures of cancer cells: an anticancer drug testing model", pages = "21-21", number = "1S", volume = "78", url = "https://hdl.handle.net/21.15107/rcub_imagine_2364" }
Petrović, J., Pańczyszyn, E., Corazzari, M., Banićević, I., Milivojević, M., Bojić, L., Stevanović, M., Dragoj, M., Pešić, M., Janković, R., Obradović, B.,& Stojkovska, J.. (2024). Adaptable alginate-based microfibers for 3D in vitro cultures of cancer cells: an anticancer drug testing model. in Hemijska industrija (Chemical Industry), 78(1S), 21-21. https://hdl.handle.net/21.15107/rcub_imagine_2364
Petrović J, Pańczyszyn E, Corazzari M, Banićević I, Milivojević M, Bojić L, Stevanović M, Dragoj M, Pešić M, Janković R, Obradović B, Stojkovska J. Adaptable alginate-based microfibers for 3D in vitro cultures of cancer cells: an anticancer drug testing model. in Hemijska industrija (Chemical Industry). 2024;78(1S):21-21. https://hdl.handle.net/21.15107/rcub_imagine_2364 .
Petrović, Jelena, Pańczyszyn, Elżbieta, Corazzari, Marco, Banićević, Ivana, Milivojević, Milena, Bojić, Luka, Stevanović, Milena, Dragoj, Miodrag, Pešić, Milica, Janković, Radmila, Obradović, Bojana, Stojkovska, Jasmina, "Adaptable alginate-based microfibers for 3D in vitro cultures of cancer cells: an anticancer drug testing model" in Hemijska industrija (Chemical Industry), 78, no. 1S (2024):21-21, https://hdl.handle.net/21.15107/rcub_imagine_2364 .