dc.contributor | Kovačević, Zoran | |
dc.creator | Novović, Katarina | |
dc.creator | Matijašević, Danka | |
dc.creator | Malešević, Milka | |
dc.date.accessioned | 2024-06-11T19:14:06Z | |
dc.date.available | 2024-06-11T19:14:06Z | |
dc.date.issued | 2024 | |
dc.identifier.isbn | 978-86-7520-610-1 | |
dc.identifier.uri | https://imagine.imgge.bg.ac.rs/handle/123456789/2398 | |
dc.description.abstract | Antimicrobial resistance (AMR) and air pollution have been
identified as one of the most serious threats to human health
worldwide. The scarce data demonstrating their interdependence
indicates a need to obtain evidence from a broader global area,
especially from regions exposed to high air pollution. Considering
that Serbia is a country struggling with excessive antibiotics use and
misuse, a high percentage of multidrug-resistant bacterial isolates,
and poor air quality, the Serbian capital Belgrade has been recognized
as an interesting research model for the effects of air pollution on the
airborne transmission of AMR. Hence, this abstract aims to present the concept of an ongoing project (AirPollRes) that points to the
additional risk dimension of air pollution to human, animal, and
environmental health. After optimization of air sampling and DNA
extraction protocol, the air samples will be collected at nine locations
in the Belgrade metropolitan area selected according to air pollution
level during four seasons. The state-of-the-art shotgun metagenomic
sequencing and bioinformatic analysis of obtained sequences will
provide information about microbial community composition of
airborne metagenomes. In addition, sequenced airborne
metagenomes will be analyzed for the abundance and diversity of
resistomes (antibiotic and biocide/metal resistance genes) and
mobilomes using several databases and tools. Correlation analyses
will offer us insight into the effect of air pollution and seasonal
variations on abundance and diversity of airborne pathogens,
resistome and mobilome in the Belgrade metropolitan area. In-depth
approach of the AirPollRes project will provide the first insights into
intersection of AMR and air pollution in the Belgrade metropolitan
area, which is highly vulnerable to these health threats. As the AirPollRes is a pioneering project in this field, the expected shortterm
impact is the introduction of routine monitoring of pathogenic
microbes and resistance determinants in the air in Belgrade, while the
longer-term impact will be reflected in the improvement of human
and animal health, allowing for a longer life with higher quality. | sr |
dc.language.iso | en | sr |
dc.publisher | Novi Sad : Faculty of Agriculture | sr |
dc.relation | info:eu-repo/grantAgreement/ScienceFundRS/Promis2023/10933/RS// | sr |
dc.rights | openAccess | sr |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.source | 3nd International conference Antimicrobial Resistance – current state and perspectives | sr |
dc.subject | antimicrobial resistance | sr |
dc.subject | air pollution | sr |
dc.subject | airborne metagenome | sr |
dc.subject | resistome | sr |
dc.subject | mobilome | sr |
dc.subject | Belgrade | sr |
dc.title | ASSESSMENT OF SEASONAL AIRBORNE RESISTOME DYNAMICS IN RESPONSE TO AIR POLLUTION EXPOSURE IN THE BELGRADE METRPOLITAN AREA | sr |
dc.type | conferenceObject | sr |
dc.rights.license | BY-NC-ND | sr |
dc.citation.epage | 122 | |
dc.citation.spage | 120 | |
dc.description.other | Book of abstracts and conference proceedings / 3rd International Conference Antimicrobial Resistance - Current State and Perspectives, 16-18. May 2024, Novi Sad, Serbia | sr |
dc.identifier.fulltext | https://imagine.imgge.bg.ac.rs/bitstream/id/845494/bitstream_845494.pdf | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_imagine_2398 | |
dc.type.version | publishedVersion | sr |