ANTIOXIDANT AND ANTIPROLIFERATIVE ACTIVITY OF PLANT BIOACTIVE COMPOUNDS DURING IN VITRO SIMULATED DIGESTION IN THE PRESENCE OF FOOD MATRIX
Autori
Samardžić, JelenaŠavikin, Katarina
Golić, Nataša
Soković Bajić, Svetlana
Stanisavljević, Nemanja
Ostala autorstva
Bajrović, KasimKonferencijski prilog (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
One of the key factors that can hinder the beneficial effects of bioactive compounds found in food is
their bioavailability, which is contingent upon their digestive stability, release from the food matrix,
and efficiency in passing through the epithelial barrier. Our study investigated the impact of in vitro
digestion and the food matrix on polyphenols from chokeberry fruits and organosulfur compounds from
ramsons. Our results indicate that despite the significant transformation of chokeberry phenolics during
digestion in the presence of the food matrix, they retain their potency as antioxidants and
antiproliferative agents. Research on ramsons (Allium ursinum) suggests that its consumption may
provide health benefits, particularly regarding potential anticancer properties. The safety characteristics
of Lactobacillus fermentum strains associated with A. ursinum, including the absence of gelatinase and
hemolytic activity, susceptibility to clinically relevant antibiotics, and ...beneficial properties such as
survival in the simulated gastrointestinal environment, colonization of the intestinal mucosa, and
immunomodulatory effects, indicate their potential use as probiotics for human consumption. This
study represents the first comprehensive analysis of ramsons' antioxidant and antiproliferative
properties, followed by an investigation into its microbiota and the health-promoting effects of lactic
acid bacteria (LAB).
Ključne reči:
bioactive compounds / bioavailability / in vitro digestion / food matrix / lactic acid bacteriaIzvor:
Genetics&Applications, 2024, Special Edition, 11-11Izdavač:
- Sarajevo : Institute for Genetic Engineering and Biotechnology, University of Sarajevo
Napomena:
- Book of abstracts: 2nd European Symposium on Phytochemicals in Medicine and Food 2-EuSPMF June, 2024
Kolekcije
- Radovi istraživača / Researchers’ publications
- Grupa za molekularnu mikrobiologiju/ Group for Molecular Microbiology 06
- Grupa za molekularnu biologiju biljaka/ Group for Plant Molecular Biology 08
- Grupa za interakcije probiotika i mikrobiote sa domaćinom/ Group for Probiotics and Microbiota-Host Interaction 09
Institucija/grupa
Institut za molekularnu genetiku i genetičko inženjerstvoTY - CONF AU - Samardžić, Jelena AU - Šavikin, Katarina AU - Golić, Nataša AU - Soković Bajić, Svetlana AU - Stanisavljević, Nemanja PY - 2024 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/2499 AB - One of the key factors that can hinder the beneficial effects of bioactive compounds found in food is their bioavailability, which is contingent upon their digestive stability, release from the food matrix, and efficiency in passing through the epithelial barrier. Our study investigated the impact of in vitro digestion and the food matrix on polyphenols from chokeberry fruits and organosulfur compounds from ramsons. Our results indicate that despite the significant transformation of chokeberry phenolics during digestion in the presence of the food matrix, they retain their potency as antioxidants and antiproliferative agents. Research on ramsons (Allium ursinum) suggests that its consumption may provide health benefits, particularly regarding potential anticancer properties. The safety characteristics of Lactobacillus fermentum strains associated with A. ursinum, including the absence of gelatinase and hemolytic activity, susceptibility to clinically relevant antibiotics, and beneficial properties such as survival in the simulated gastrointestinal environment, colonization of the intestinal mucosa, and immunomodulatory effects, indicate their potential use as probiotics for human consumption. This study represents the first comprehensive analysis of ramsons' antioxidant and antiproliferative properties, followed by an investigation into its microbiota and the health-promoting effects of lactic acid bacteria (LAB). PB - Sarajevo : Institute for Genetic Engineering and Biotechnology, University of Sarajevo C3 - Genetics&Applications T1 - ANTIOXIDANT AND ANTIPROLIFERATIVE ACTIVITY OF PLANT BIOACTIVE COMPOUNDS DURING IN VITRO SIMULATED DIGESTION IN THE PRESENCE OF FOOD MATRIX EP - 11 IS - Special Edition SP - 11 UR - https://hdl.handle.net/21.15107/rcub_imagine_2499 ER -
@conference{ author = "Samardžić, Jelena and Šavikin, Katarina and Golić, Nataša and Soković Bajić, Svetlana and Stanisavljević, Nemanja", year = "2024", abstract = "One of the key factors that can hinder the beneficial effects of bioactive compounds found in food is their bioavailability, which is contingent upon their digestive stability, release from the food matrix, and efficiency in passing through the epithelial barrier. Our study investigated the impact of in vitro digestion and the food matrix on polyphenols from chokeberry fruits and organosulfur compounds from ramsons. Our results indicate that despite the significant transformation of chokeberry phenolics during digestion in the presence of the food matrix, they retain their potency as antioxidants and antiproliferative agents. Research on ramsons (Allium ursinum) suggests that its consumption may provide health benefits, particularly regarding potential anticancer properties. The safety characteristics of Lactobacillus fermentum strains associated with A. ursinum, including the absence of gelatinase and hemolytic activity, susceptibility to clinically relevant antibiotics, and beneficial properties such as survival in the simulated gastrointestinal environment, colonization of the intestinal mucosa, and immunomodulatory effects, indicate their potential use as probiotics for human consumption. This study represents the first comprehensive analysis of ramsons' antioxidant and antiproliferative properties, followed by an investigation into its microbiota and the health-promoting effects of lactic acid bacteria (LAB).", publisher = "Sarajevo : Institute for Genetic Engineering and Biotechnology, University of Sarajevo", journal = "Genetics&Applications", title = "ANTIOXIDANT AND ANTIPROLIFERATIVE ACTIVITY OF PLANT BIOACTIVE COMPOUNDS DURING IN VITRO SIMULATED DIGESTION IN THE PRESENCE OF FOOD MATRIX", pages = "11-11", number = "Special Edition", url = "https://hdl.handle.net/21.15107/rcub_imagine_2499" }
Samardžić, J., Šavikin, K., Golić, N., Soković Bajić, S.,& Stanisavljević, N.. (2024). ANTIOXIDANT AND ANTIPROLIFERATIVE ACTIVITY OF PLANT BIOACTIVE COMPOUNDS DURING IN VITRO SIMULATED DIGESTION IN THE PRESENCE OF FOOD MATRIX. in Genetics&Applications Sarajevo : Institute for Genetic Engineering and Biotechnology, University of Sarajevo.(Special Edition), 11-11. https://hdl.handle.net/21.15107/rcub_imagine_2499
Samardžić J, Šavikin K, Golić N, Soković Bajić S, Stanisavljević N. ANTIOXIDANT AND ANTIPROLIFERATIVE ACTIVITY OF PLANT BIOACTIVE COMPOUNDS DURING IN VITRO SIMULATED DIGESTION IN THE PRESENCE OF FOOD MATRIX. in Genetics&Applications. 2024;(Special Edition):11-11. https://hdl.handle.net/21.15107/rcub_imagine_2499 .
Samardžić, Jelena, Šavikin, Katarina, Golić, Nataša, Soković Bajić, Svetlana, Stanisavljević, Nemanja, "ANTIOXIDANT AND ANTIPROLIFERATIVE ACTIVITY OF PLANT BIOACTIVE COMPOUNDS DURING IN VITRO SIMULATED DIGESTION IN THE PRESENCE OF FOOD MATRIX" in Genetics&Applications, no. Special Edition (2024):11-11, https://hdl.handle.net/21.15107/rcub_imagine_2499 .