Diffuse osteolytic lesions in leukemic transformation of myelofibrosis
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Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Myelofibrosis is a clonal myeloproliferative disorder characterized by splenomegaly, abnormal deposition of reticulin and collagen in the bone marrow, extramedullary hematopoiesis, dacryocytosis and leukoerythroblastic blood smear. Development and sustainment of fibrosis are mediated by complex network of several cytokines. Osteosclerosis is the most frequently observed bone change in myelofibrosis. We present an atypical case of leukemic transformation in myelofibrosis associated with diffuse osteolytic lesions and extremely elevated lactate dehydrogenase in serum, which indicates high bone turnover during leukemic infiltration and bone destruction.
Ključne reči:
parathyroid hormone / osteolysis / neoplastic / myeloid / myelofibrosis / leukemia / lactate dehydrogenases / cell transformationIzvor:
Archive of Oncology, 2007, 15, 1-2, 45-47Izdavač:
- Institut za onkologiju, Sremska Kamenica
Institucija/grupa
Institut za molekularnu genetiku i genetičko inženjerstvoTY - JOUR AU - Jurišić, Vladimir AU - Čolović, Nataša AU - Pavlović, Sonja AU - Čolović, Milica PY - 2007 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/292 AB - Myelofibrosis is a clonal myeloproliferative disorder characterized by splenomegaly, abnormal deposition of reticulin and collagen in the bone marrow, extramedullary hematopoiesis, dacryocytosis and leukoerythroblastic blood smear. Development and sustainment of fibrosis are mediated by complex network of several cytokines. Osteosclerosis is the most frequently observed bone change in myelofibrosis. We present an atypical case of leukemic transformation in myelofibrosis associated with diffuse osteolytic lesions and extremely elevated lactate dehydrogenase in serum, which indicates high bone turnover during leukemic infiltration and bone destruction. PB - Institut za onkologiju, Sremska Kamenica T2 - Archive of Oncology T1 - Diffuse osteolytic lesions in leukemic transformation of myelofibrosis EP - 47 IS - 1-2 SP - 45 VL - 15 DO - 10.2298/AOO0702045J ER -
@article{ author = "Jurišić, Vladimir and Čolović, Nataša and Pavlović, Sonja and Čolović, Milica", year = "2007", abstract = "Myelofibrosis is a clonal myeloproliferative disorder characterized by splenomegaly, abnormal deposition of reticulin and collagen in the bone marrow, extramedullary hematopoiesis, dacryocytosis and leukoerythroblastic blood smear. Development and sustainment of fibrosis are mediated by complex network of several cytokines. Osteosclerosis is the most frequently observed bone change in myelofibrosis. We present an atypical case of leukemic transformation in myelofibrosis associated with diffuse osteolytic lesions and extremely elevated lactate dehydrogenase in serum, which indicates high bone turnover during leukemic infiltration and bone destruction.", publisher = "Institut za onkologiju, Sremska Kamenica", journal = "Archive of Oncology", title = "Diffuse osteolytic lesions in leukemic transformation of myelofibrosis", pages = "47-45", number = "1-2", volume = "15", doi = "10.2298/AOO0702045J" }
Jurišić, V., Čolović, N., Pavlović, S.,& Čolović, M.. (2007). Diffuse osteolytic lesions in leukemic transformation of myelofibrosis. in Archive of Oncology Institut za onkologiju, Sremska Kamenica., 15(1-2), 45-47. https://doi.org/10.2298/AOO0702045J
Jurišić V, Čolović N, Pavlović S, Čolović M. Diffuse osteolytic lesions in leukemic transformation of myelofibrosis. in Archive of Oncology. 2007;15(1-2):45-47. doi:10.2298/AOO0702045J .
Jurišić, Vladimir, Čolović, Nataša, Pavlović, Sonja, Čolović, Milica, "Diffuse osteolytic lesions in leukemic transformation of myelofibrosis" in Archive of Oncology, 15, no. 1-2 (2007):45-47, https://doi.org/10.2298/AOO0702045J . .