Model-based evolutionary analysis: the natural history of phage-shock stress response
Само за регистроване кориснике
2009
Аутори
Huvet, MaximeToni, Tina
Tan, Hui
Jovanović, Goran
Engl, Christoph
Buck, Martin
Stumpf, Michael P. H.
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The evolution of proteins is inseparably linked to their function. Because most biological processes involve a number of different proteins, it may become impossible to study the evolutionary properties of proteins in isolation. In the present article, we show how simple mechanistic models of biological processes can complement conventional comparative analyses of biological traits. We use the specific example of the phage-shock stress response, which has been well characterized in Escherichia coli, to elucidate patterns of gene sharing and sequence conservation across bacterial species.
Кључне речи:
sequence conservation / phage-shock stress response / gene sharing / evolutionary analysis / bacteriumИзвор:
Biochemical Society Transactions, 2009, 37, 762-767Издавач:
- Portland Press Ltd, London
Финансирање / пројекти:
- Biotechnology and Biological Sciences Research Council [BB/C519670/1, BB/F005210/1, BB/G00594X/1, BB/F013566/1] Funding Source: Medline
- Medical Research Council Funding Source: Medline
- Wellcome Trust [080000] Funding Source: Medline
- BBSRC [BB/F005210/1, BB/F013566/1, BB/G00594X/1] Funding Source: UKRI
DOI: 10.1042/BST0370762
ISSN: 0300-5127
PubMed: 19614590
WoS: 000268902800024
Scopus: 2-s2.0-70349329177
Институција/група
Institut za molekularnu genetiku i genetičko inženjerstvoTY - CONF AU - Huvet, Maxime AU - Toni, Tina AU - Tan, Hui AU - Jovanović, Goran AU - Engl, Christoph AU - Buck, Martin AU - Stumpf, Michael P. H. PY - 2009 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/351 AB - The evolution of proteins is inseparably linked to their function. Because most biological processes involve a number of different proteins, it may become impossible to study the evolutionary properties of proteins in isolation. In the present article, we show how simple mechanistic models of biological processes can complement conventional comparative analyses of biological traits. We use the specific example of the phage-shock stress response, which has been well characterized in Escherichia coli, to elucidate patterns of gene sharing and sequence conservation across bacterial species. PB - Portland Press Ltd, London C3 - Biochemical Society Transactions T1 - Model-based evolutionary analysis: the natural history of phage-shock stress response EP - 767 SP - 762 VL - 37 DO - 10.1042/BST0370762 ER -
@conference{ author = "Huvet, Maxime and Toni, Tina and Tan, Hui and Jovanović, Goran and Engl, Christoph and Buck, Martin and Stumpf, Michael P. H.", year = "2009", abstract = "The evolution of proteins is inseparably linked to their function. Because most biological processes involve a number of different proteins, it may become impossible to study the evolutionary properties of proteins in isolation. In the present article, we show how simple mechanistic models of biological processes can complement conventional comparative analyses of biological traits. We use the specific example of the phage-shock stress response, which has been well characterized in Escherichia coli, to elucidate patterns of gene sharing and sequence conservation across bacterial species.", publisher = "Portland Press Ltd, London", journal = "Biochemical Society Transactions", title = "Model-based evolutionary analysis: the natural history of phage-shock stress response", pages = "767-762", volume = "37", doi = "10.1042/BST0370762" }
Huvet, M., Toni, T., Tan, H., Jovanović, G., Engl, C., Buck, M.,& Stumpf, M. P. H.. (2009). Model-based evolutionary analysis: the natural history of phage-shock stress response. in Biochemical Society Transactions Portland Press Ltd, London., 37, 762-767. https://doi.org/10.1042/BST0370762
Huvet M, Toni T, Tan H, Jovanović G, Engl C, Buck M, Stumpf MPH. Model-based evolutionary analysis: the natural history of phage-shock stress response. in Biochemical Society Transactions. 2009;37:762-767. doi:10.1042/BST0370762 .
Huvet, Maxime, Toni, Tina, Tan, Hui, Jovanović, Goran, Engl, Christoph, Buck, Martin, Stumpf, Michael P. H., "Model-based evolutionary analysis: the natural history of phage-shock stress response" in Biochemical Society Transactions, 37 (2009):762-767, https://doi.org/10.1042/BST0370762 . .