Molecular response to imatinib in patient with Ph negative p190 BCR-ABL transcript positive chronic myeloid leukemia with cyclic leukocytosis
Само за регистроване кориснике
2009
Информативни прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
An atypical case of Philadelphia (Ph) negative, e1a2 BCR-ABL transcript positive chronic myeloid leukemia (CML) characterized with cyclic periodic leukocytosis and spontaneous remissions is reported. The patient was treated with imatinib and good hematology response with molecular remission was achieved. So far, only few Ph positive CML patients expressing p190 BCR-ABL protein and different clinical characteristics and treatment have been described in the literature. This is the first report of Philadelphia negative, p190 BCR-ABL positive CML with cyclic spontaneous oscillation of white blood cell count (WBC), and excellent response to imatinib treatment.
Кључне речи:
Ph negative CML / Imatinib / BCR-ABL e1a2Извор:
Leukemia Research, 2009, 33, 6, e10-e12Финансирање / пројекти:
- Молекуларно генетски маркери клонског преображаја матичних ћелија хематопоезе (RS-MESTD-MPN2006-2010-145061)
DOI: 10.1016/j.leukres.2008.10.028
ISSN: 0145-2126
PubMed: 19091403
Scopus: 2-s2.0-63649112380
Институција/група
Institut za molekularnu genetiku i genetičko inženjerstvoTY - JOUR AU - Radojković, M. AU - Ristić, S. AU - Pavlović, Sonja AU - Colović, M. PY - 2009 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/388 AB - An atypical case of Philadelphia (Ph) negative, e1a2 BCR-ABL transcript positive chronic myeloid leukemia (CML) characterized with cyclic periodic leukocytosis and spontaneous remissions is reported. The patient was treated with imatinib and good hematology response with molecular remission was achieved. So far, only few Ph positive CML patients expressing p190 BCR-ABL protein and different clinical characteristics and treatment have been described in the literature. This is the first report of Philadelphia negative, p190 BCR-ABL positive CML with cyclic spontaneous oscillation of white blood cell count (WBC), and excellent response to imatinib treatment. T2 - Leukemia Research T1 - Molecular response to imatinib in patient with Ph negative p190 BCR-ABL transcript positive chronic myeloid leukemia with cyclic leukocytosis EP - e12 IS - 6 SP - e10 VL - 33 DO - 10.1016/j.leukres.2008.10.028 ER -
@article{ author = "Radojković, M. and Ristić, S. and Pavlović, Sonja and Colović, M.", year = "2009", abstract = "An atypical case of Philadelphia (Ph) negative, e1a2 BCR-ABL transcript positive chronic myeloid leukemia (CML) characterized with cyclic periodic leukocytosis and spontaneous remissions is reported. The patient was treated with imatinib and good hematology response with molecular remission was achieved. So far, only few Ph positive CML patients expressing p190 BCR-ABL protein and different clinical characteristics and treatment have been described in the literature. This is the first report of Philadelphia negative, p190 BCR-ABL positive CML with cyclic spontaneous oscillation of white blood cell count (WBC), and excellent response to imatinib treatment.", journal = "Leukemia Research", title = "Molecular response to imatinib in patient with Ph negative p190 BCR-ABL transcript positive chronic myeloid leukemia with cyclic leukocytosis", pages = "e12-e10", number = "6", volume = "33", doi = "10.1016/j.leukres.2008.10.028" }
Radojković, M., Ristić, S., Pavlović, S.,& Colović, M.. (2009). Molecular response to imatinib in patient with Ph negative p190 BCR-ABL transcript positive chronic myeloid leukemia with cyclic leukocytosis. in Leukemia Research, 33(6), e10-e12. https://doi.org/10.1016/j.leukres.2008.10.028
Radojković M, Ristić S, Pavlović S, Colović M. Molecular response to imatinib in patient with Ph negative p190 BCR-ABL transcript positive chronic myeloid leukemia with cyclic leukocytosis. in Leukemia Research. 2009;33(6):e10-e12. doi:10.1016/j.leukres.2008.10.028 .
Radojković, M., Ristić, S., Pavlović, Sonja, Colović, M., "Molecular response to imatinib in patient with Ph negative p190 BCR-ABL transcript positive chronic myeloid leukemia with cyclic leukocytosis" in Leukemia Research, 33, no. 6 (2009):e10-e12, https://doi.org/10.1016/j.leukres.2008.10.028 . .