The in vitro antioxidative and cytotoxic effects of selected Salvia species water extracts
2015
Аутори
Alimpić, AnaKotur, Nikola
Stanković, Biljana
Marin, Petar D.
Matevski, Vlado
Al Sheef, Najat Beleed
Duletić-Lausević, Sonja
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The current paper presents antioxidant and cytotoxic activities and total phenolic and flavonoid content of the selected species of genus Salvia (Lamiaceae) growing wild in Macedonia (S. jurisicii Kosanin, S. amplexicaulis Lam., S. ringens Sibth. & Sm.) and Libya (S. fruticosa Mill. and S. lanigera Poir.). Crude water extracts, obtained from aerial parts, were yielded from 6.50 to 14.32%. Total phenolic content was the highest in water extracts of S. amplexicaulis and S. ringens (226.30 and 189.01 mg GAE/g, respectively), while the flavonoids were the most abundant in S. jurisicii extract (32.36 mg QE/g). Antioxidant activities of extracts were measured using DPPH, ABTS and FRAP assays. S. amplexicaulis and S. ringens extracts showed the strongest antioxidant activity, measured using DPPH (14.21 and 23.44 mu g/mL, respectively) and ABTS assays (2.91 and 2.42 mg AAE/g, respectively). In FRAP assay, S. amplexicaulis and S. fruticosa extracts exhibited strongest activity (1406.73 and 1191....51 mu mol Fe(II)/g). Water extract of S. amplexicaulis and S. ringens performed the strongest cytotoxic activity against K562 cells (151.07 and 173.06 mu g/mL, respectively). Based on these findings, it can be concluded that S. amplexicaulis and S. ringens water extracts could be considered as possible source of antioxidant and cytotoxic agents.
Извор:
Journal of Applied Botany and Food Quality, 2015, 88, 115-119Издавач:
- Druckerei Liddy Halm, Gottingen
Финансирање / пројекти:
- Микроморфолошка, фитохемијска и молекуларна истраживања биљака - систематски, еколошки и применљиви аспекти (RS-MESTD-Basic Research (BR or ON)-173029)
- Ретке болести: молекуларна патофизиологија, дијагностички и терапијски модалитети и социјални, етички и правни аспекти (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41004)
DOI: 10.5073/JABFQ.2015.088.016
ISSN: 1439-040X
WoS: 000357932400006
Scopus: 2-s2.0-84945189845
Институција/група
Institut za molekularnu genetiku i genetičko inženjerstvoTY - JOUR AU - Alimpić, Ana AU - Kotur, Nikola AU - Stanković, Biljana AU - Marin, Petar D. AU - Matevski, Vlado AU - Al Sheef, Najat Beleed AU - Duletić-Lausević, Sonja PY - 2015 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/795 AB - The current paper presents antioxidant and cytotoxic activities and total phenolic and flavonoid content of the selected species of genus Salvia (Lamiaceae) growing wild in Macedonia (S. jurisicii Kosanin, S. amplexicaulis Lam., S. ringens Sibth. & Sm.) and Libya (S. fruticosa Mill. and S. lanigera Poir.). Crude water extracts, obtained from aerial parts, were yielded from 6.50 to 14.32%. Total phenolic content was the highest in water extracts of S. amplexicaulis and S. ringens (226.30 and 189.01 mg GAE/g, respectively), while the flavonoids were the most abundant in S. jurisicii extract (32.36 mg QE/g). Antioxidant activities of extracts were measured using DPPH, ABTS and FRAP assays. S. amplexicaulis and S. ringens extracts showed the strongest antioxidant activity, measured using DPPH (14.21 and 23.44 mu g/mL, respectively) and ABTS assays (2.91 and 2.42 mg AAE/g, respectively). In FRAP assay, S. amplexicaulis and S. fruticosa extracts exhibited strongest activity (1406.73 and 1191.51 mu mol Fe(II)/g). Water extract of S. amplexicaulis and S. ringens performed the strongest cytotoxic activity against K562 cells (151.07 and 173.06 mu g/mL, respectively). Based on these findings, it can be concluded that S. amplexicaulis and S. ringens water extracts could be considered as possible source of antioxidant and cytotoxic agents. PB - Druckerei Liddy Halm, Gottingen T2 - Journal of Applied Botany and Food Quality T1 - The in vitro antioxidative and cytotoxic effects of selected Salvia species water extracts EP - 119 SP - 115 VL - 88 DO - 10.5073/JABFQ.2015.088.016 ER -
@article{ author = "Alimpić, Ana and Kotur, Nikola and Stanković, Biljana and Marin, Petar D. and Matevski, Vlado and Al Sheef, Najat Beleed and Duletić-Lausević, Sonja", year = "2015", abstract = "The current paper presents antioxidant and cytotoxic activities and total phenolic and flavonoid content of the selected species of genus Salvia (Lamiaceae) growing wild in Macedonia (S. jurisicii Kosanin, S. amplexicaulis Lam., S. ringens Sibth. & Sm.) and Libya (S. fruticosa Mill. and S. lanigera Poir.). Crude water extracts, obtained from aerial parts, were yielded from 6.50 to 14.32%. Total phenolic content was the highest in water extracts of S. amplexicaulis and S. ringens (226.30 and 189.01 mg GAE/g, respectively), while the flavonoids were the most abundant in S. jurisicii extract (32.36 mg QE/g). Antioxidant activities of extracts were measured using DPPH, ABTS and FRAP assays. S. amplexicaulis and S. ringens extracts showed the strongest antioxidant activity, measured using DPPH (14.21 and 23.44 mu g/mL, respectively) and ABTS assays (2.91 and 2.42 mg AAE/g, respectively). In FRAP assay, S. amplexicaulis and S. fruticosa extracts exhibited strongest activity (1406.73 and 1191.51 mu mol Fe(II)/g). Water extract of S. amplexicaulis and S. ringens performed the strongest cytotoxic activity against K562 cells (151.07 and 173.06 mu g/mL, respectively). Based on these findings, it can be concluded that S. amplexicaulis and S. ringens water extracts could be considered as possible source of antioxidant and cytotoxic agents.", publisher = "Druckerei Liddy Halm, Gottingen", journal = "Journal of Applied Botany and Food Quality", title = "The in vitro antioxidative and cytotoxic effects of selected Salvia species water extracts", pages = "119-115", volume = "88", doi = "10.5073/JABFQ.2015.088.016" }
Alimpić, A., Kotur, N., Stanković, B., Marin, P. D., Matevski, V., Al Sheef, N. B.,& Duletić-Lausević, S.. (2015). The in vitro antioxidative and cytotoxic effects of selected Salvia species water extracts. in Journal of Applied Botany and Food Quality Druckerei Liddy Halm, Gottingen., 88, 115-119. https://doi.org/10.5073/JABFQ.2015.088.016
Alimpić A, Kotur N, Stanković B, Marin PD, Matevski V, Al Sheef NB, Duletić-Lausević S. The in vitro antioxidative and cytotoxic effects of selected Salvia species water extracts. in Journal of Applied Botany and Food Quality. 2015;88:115-119. doi:10.5073/JABFQ.2015.088.016 .
Alimpić, Ana, Kotur, Nikola, Stanković, Biljana, Marin, Petar D., Matevski, Vlado, Al Sheef, Najat Beleed, Duletić-Lausević, Sonja, "The in vitro antioxidative and cytotoxic effects of selected Salvia species water extracts" in Journal of Applied Botany and Food Quality, 88 (2015):115-119, https://doi.org/10.5073/JABFQ.2015.088.016 . .