Promoter order strategy and bacterial PspF regulon evolution
Само за регистроване кориснике
2015
Поглавље у монографији (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Successful gene regulation that governs the information flow from DNA underpins programs of differentiation and adaptation across all kingdoms of life. Transcription in bacteria is controlled by RNA polymerase containing the housekeeping sigma factor(s) or the alternative, e.g. sigma54 factor, its function being regulated via bacterial enhancer binding proteins. Elaboration of the enhancer DNA sequence acting in cis with the RNA polymerase is believed to drive species diversification through enlargement and finessing of regulons that help cells survive stresses and become more complex. The cellular adaptation and associated gene expression can translate to heterogeneity across cell populations, potentially causing physiological diversity that leads to successful and stable colonisation of ecological niches under unstable changing environments typically faced by bacteria. Here, we present the Phage shock protein F (PspF) regulon as a model system to describe the actions and dynamics of ...cis- and trans-regulatory elements that govern the control of sigma54-dependent transcription of psp genes leading to adaptation of enterobacteria to the inner membrane stress. We discuss how the interplay of psp expression control elements may influence the evolution of bacterial regulon.
Извор:
Evolutionary Biology: Biodiversification from Genotype to Phenotype, 2015, 263-283Издавач:
- Springer International Publishing
Институција/група
Institut za molekularnu genetiku i genetičko inženjerstvoTY - CHAP AU - Jovanović, Goran AU - Mehta, P. AU - McDonald, C. AU - Buck, M. PY - 2015 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/864 AB - Successful gene regulation that governs the information flow from DNA underpins programs of differentiation and adaptation across all kingdoms of life. Transcription in bacteria is controlled by RNA polymerase containing the housekeeping sigma factor(s) or the alternative, e.g. sigma54 factor, its function being regulated via bacterial enhancer binding proteins. Elaboration of the enhancer DNA sequence acting in cis with the RNA polymerase is believed to drive species diversification through enlargement and finessing of regulons that help cells survive stresses and become more complex. The cellular adaptation and associated gene expression can translate to heterogeneity across cell populations, potentially causing physiological diversity that leads to successful and stable colonisation of ecological niches under unstable changing environments typically faced by bacteria. Here, we present the Phage shock protein F (PspF) regulon as a model system to describe the actions and dynamics of cis- and trans-regulatory elements that govern the control of sigma54-dependent transcription of psp genes leading to adaptation of enterobacteria to the inner membrane stress. We discuss how the interplay of psp expression control elements may influence the evolution of bacterial regulon. PB - Springer International Publishing T2 - Evolutionary Biology: Biodiversification from Genotype to Phenotype T1 - Promoter order strategy and bacterial PspF regulon evolution EP - 283 SP - 263 DO - 10.1007/978-3-319-19932-0_14 ER -
@inbook{ author = "Jovanović, Goran and Mehta, P. and McDonald, C. and Buck, M.", year = "2015", abstract = "Successful gene regulation that governs the information flow from DNA underpins programs of differentiation and adaptation across all kingdoms of life. Transcription in bacteria is controlled by RNA polymerase containing the housekeeping sigma factor(s) or the alternative, e.g. sigma54 factor, its function being regulated via bacterial enhancer binding proteins. Elaboration of the enhancer DNA sequence acting in cis with the RNA polymerase is believed to drive species diversification through enlargement and finessing of regulons that help cells survive stresses and become more complex. The cellular adaptation and associated gene expression can translate to heterogeneity across cell populations, potentially causing physiological diversity that leads to successful and stable colonisation of ecological niches under unstable changing environments typically faced by bacteria. Here, we present the Phage shock protein F (PspF) regulon as a model system to describe the actions and dynamics of cis- and trans-regulatory elements that govern the control of sigma54-dependent transcription of psp genes leading to adaptation of enterobacteria to the inner membrane stress. We discuss how the interplay of psp expression control elements may influence the evolution of bacterial regulon.", publisher = "Springer International Publishing", journal = "Evolutionary Biology: Biodiversification from Genotype to Phenotype", booktitle = "Promoter order strategy and bacterial PspF regulon evolution", pages = "283-263", doi = "10.1007/978-3-319-19932-0_14" }
Jovanović, G., Mehta, P., McDonald, C.,& Buck, M.. (2015). Promoter order strategy and bacterial PspF regulon evolution. in Evolutionary Biology: Biodiversification from Genotype to Phenotype Springer International Publishing., 263-283. https://doi.org/10.1007/978-3-319-19932-0_14
Jovanović G, Mehta P, McDonald C, Buck M. Promoter order strategy and bacterial PspF regulon evolution. in Evolutionary Biology: Biodiversification from Genotype to Phenotype. 2015;:263-283. doi:10.1007/978-3-319-19932-0_14 .
Jovanović, Goran, Mehta, P., McDonald, C., Buck, M., "Promoter order strategy and bacterial PspF regulon evolution" in Evolutionary Biology: Biodiversification from Genotype to Phenotype (2015):263-283, https://doi.org/10.1007/978-3-319-19932-0_14 . .