The Disbalance of α- and β-Globins in Anemic Belgrade Rat Red Blood Cells
Само за регистроване кориснике
1994
Аутори
Marjanoviċ, J.Savkoviċ, S.
Nikčević, Gordana
Glišin, V.
Ivanoviċ, Z.
Milenkoviċ, P.
Popoviċ, Z.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The Belgrade Laboratory (b/b) rat has an autosomal mutation which in homozygous state induces severe anemia. This study was based on solubilization of total rat globin chains and their separation into α- and β-globins using a 20% SDS polyacrilamide gel. These analyses demonstrated that the disbalance of α/β globins in b/b red blood cells (RBC) is due to decreased level of α-globins. Iron-dextran administration corrected the level and globin ratio in b/b RBC thus confirming that the iron deficiency is the primary defect in b/b rats.
Извор:
Biochemical and Biophysical Research Communications, 1994, 201, 1, 115-122
DOI: 10.1006/bbrc.1994.1676
ISSN: 0006-291X
PubMed: 8198563
Scopus: 2-s2.0-0028240833
Институција/група
Institut za molekularnu genetiku i genetičko inženjerstvoTY - JOUR AU - Marjanoviċ, J. AU - Savkoviċ, S. AU - Nikčević, Gordana AU - Glišin, V. AU - Ivanoviċ, Z. AU - Milenkoviċ, P. AU - Popoviċ, Z. PY - 1994 UR - https://imagine.imgge.bg.ac.rs/handle/123456789/88 AB - The Belgrade Laboratory (b/b) rat has an autosomal mutation which in homozygous state induces severe anemia. This study was based on solubilization of total rat globin chains and their separation into α- and β-globins using a 20% SDS polyacrilamide gel. These analyses demonstrated that the disbalance of α/β globins in b/b red blood cells (RBC) is due to decreased level of α-globins. Iron-dextran administration corrected the level and globin ratio in b/b RBC thus confirming that the iron deficiency is the primary defect in b/b rats. T2 - Biochemical and Biophysical Research Communications T1 - The Disbalance of α- and β-Globins in Anemic Belgrade Rat Red Blood Cells EP - 122 IS - 1 SP - 115 VL - 201 DO - 10.1006/bbrc.1994.1676 ER -
@article{ author = "Marjanoviċ, J. and Savkoviċ, S. and Nikčević, Gordana and Glišin, V. and Ivanoviċ, Z. and Milenkoviċ, P. and Popoviċ, Z.", year = "1994", abstract = "The Belgrade Laboratory (b/b) rat has an autosomal mutation which in homozygous state induces severe anemia. This study was based on solubilization of total rat globin chains and their separation into α- and β-globins using a 20% SDS polyacrilamide gel. These analyses demonstrated that the disbalance of α/β globins in b/b red blood cells (RBC) is due to decreased level of α-globins. Iron-dextran administration corrected the level and globin ratio in b/b RBC thus confirming that the iron deficiency is the primary defect in b/b rats.", journal = "Biochemical and Biophysical Research Communications", title = "The Disbalance of α- and β-Globins in Anemic Belgrade Rat Red Blood Cells", pages = "122-115", number = "1", volume = "201", doi = "10.1006/bbrc.1994.1676" }
Marjanoviċ, J., Savkoviċ, S., Nikčević, G., Glišin, V., Ivanoviċ, Z., Milenkoviċ, P.,& Popoviċ, Z.. (1994). The Disbalance of α- and β-Globins in Anemic Belgrade Rat Red Blood Cells. in Biochemical and Biophysical Research Communications, 201(1), 115-122. https://doi.org/10.1006/bbrc.1994.1676
Marjanoviċ J, Savkoviċ S, Nikčević G, Glišin V, Ivanoviċ Z, Milenkoviċ P, Popoviċ Z. The Disbalance of α- and β-Globins in Anemic Belgrade Rat Red Blood Cells. in Biochemical and Biophysical Research Communications. 1994;201(1):115-122. doi:10.1006/bbrc.1994.1676 .
Marjanoviċ, J., Savkoviċ, S., Nikčević, Gordana, Glišin, V., Ivanoviċ, Z., Milenkoviċ, P., Popoviċ, Z., "The Disbalance of α- and β-Globins in Anemic Belgrade Rat Red Blood Cells" in Biochemical and Biophysical Research Communications, 201, no. 1 (1994):115-122, https://doi.org/10.1006/bbrc.1994.1676 . .