TY  - JOUR
AU  - Milosević, Katarina
AU  - Rsovac, Snežana
AU  - Nestorović, Branimir
AU  - Nikolić, Aleksandra
PY  - 2012
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/567
AB  - The aim of this study was to investigate response to salbutamol in children with acute asthma exacerbations in order to estimate the efficiency and safety of its administration in pediatric population. The study included 56 children with asthma (age range 5-12) who were diagnosed and treated over a period of two years. In all children, salbutamol was administered via nebulization, in doses of 1.25 mg in children aged 5-6 and 2.5 mg in children aged 7-12. Respiratory and blood parameters were monitored before and 30 minutes after salbutamol administration. In children with acute asthma exacerbations, respiratory frequency, potassium level, sodium level and PaCO, decreased significantly after salbutamol administration, while PEF, PEF%, glycemia, PaO2 and SatO(2) significantly increased. Hypokalemia due to salbutanzol effect occurred in 15 (26.8%) children. Most significant improvement in oxygenation, with increase of PEF, PEF%, PaO2 and SatO(2), after salbutamol administration was achieved in patients with mild acute exacerbations. Salbulanzol administered via nebulization leads to the occurrence of adverse metabolic elfe cts, hypokalemia and hyperglycemia. Howevez; it can be safely used in the treatment of acute asthma exacerbations and demonstrates high clinical efficacy in the management of acute bronchospasm. The most effective salbutamol treatment is achieved in patients with mild exacerbations.
T2  - Paediatria Croatica
T1  - Response to salbutamol in children with acute asthma exacerbations
EP  - 208
IS  - 3
SP  - 205
VL  - 56
UR  - https://hdl.handle.net/21.15107/rcub_imagine_567
ER  - 

@article{
author = "Milosević, Katarina and Rsovac, Snežana and Nestorović, Branimir and Nikolić, Aleksandra",
year = "2012",
abstract = "The aim of this study was to investigate response to salbutamol in children with acute asthma exacerbations in order to estimate the efficiency and safety of its administration in pediatric population. The study included 56 children with asthma (age range 5-12) who were diagnosed and treated over a period of two years. In all children, salbutamol was administered via nebulization, in doses of 1.25 mg in children aged 5-6 and 2.5 mg in children aged 7-12. Respiratory and blood parameters were monitored before and 30 minutes after salbutamol administration. In children with acute asthma exacerbations, respiratory frequency, potassium level, sodium level and PaCO, decreased significantly after salbutamol administration, while PEF, PEF%, glycemia, PaO2 and SatO(2) significantly increased. Hypokalemia due to salbutanzol effect occurred in 15 (26.8%) children. Most significant improvement in oxygenation, with increase of PEF, PEF%, PaO2 and SatO(2), after salbutamol administration was achieved in patients with mild acute exacerbations. Salbulanzol administered via nebulization leads to the occurrence of adverse metabolic elfe cts, hypokalemia and hyperglycemia. Howevez; it can be safely used in the treatment of acute asthma exacerbations and demonstrates high clinical efficacy in the management of acute bronchospasm. The most effective salbutamol treatment is achieved in patients with mild exacerbations.",
journal = "Paediatria Croatica",
title = "Response to salbutamol in children with acute asthma exacerbations",
pages = "208-205",
number = "3",
volume = "56",
url = "https://hdl.handle.net/21.15107/rcub_imagine_567"
}

Milosević, K., Rsovac, S., Nestorović, B.,& Nikolić, A.. (2012). Response to salbutamol in children with acute asthma exacerbations. in Paediatria Croatica, 56(3), 205-208.
https://hdl.handle.net/21.15107/rcub_imagine_567

Milosević K, Rsovac S, Nestorović B, Nikolić A. Response to salbutamol in children with acute asthma exacerbations. in Paediatria Croatica. 2012;56(3):205-208.
https://hdl.handle.net/21.15107/rcub_imagine_567 .

Milosević, Katarina, Rsovac, Snežana, Nestorović, Branimir, Nikolić, Aleksandra, "Response to salbutamol in children with acute asthma exacerbations" in Paediatria Croatica, 56, no. 3 (2012):205-208,
https://hdl.handle.net/21.15107/rcub_imagine_567 .