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Current Opportunities for Targeting Dysregulated Neurodevelopmental Signaling Pathways in Glioblastoma
(MDPI, Basel, 2022)
Glioblastoma (GBM) is the most common and highly lethal type of brain tumor, with poor survival despite advances in understanding its complexity. After current standard therapeutic treatment, including tumor resection, ...
Electronic cigarette liquids impair metabolic cooperation and alter proteomic profiles in V79 cells
(BMC, London, 2022)
Background Although still considered a safer alternative to classical cigarettes, growing body of work points to harmful effects of electronic cigarettes (e-cigarettes) affecting a range of cellular processes. The biological ...
Meta-Analysis of Circulating Cell-Free DNA's Role in the Prognosis of Pancreatic Cancer
(MDPI, Basel, 2021)
Simple Summary Pancreatic cancer is an aggressive disease with a poor prognosis. The analysis of cell-free DNA (cfDNA) for genetic abnormalities is a promising new approach for the diagnosis and prognosis of pancreatic ...
Isolation, Characterization and Draft Genome Analysis of Bacteriophages Infecting Acidovorax citrulli
(Frontiers Media Sa, Lausanne, 2022)
Bacterial fruit blotch and seedling blight, caused by Acidovorax citrulli, is one of the most destructive diseases of melon and watermelon in many countries. Pathogen-free seed and cultural practices are major pillars of ...
Impaired Fibrinolysis Is Linked With Digital Vasculopathy and Onset of New Digital Ulcers in Systemic Sclerosis
(Toronto : J Rheumatol Publ Co., 2022)
Objective. To assess thrombin generation, fibrin formation, and structure together with the fibrinolytic status in patients with systemic sclerosis (SSc) in relation to the occurrence of digital ulcers (DUs) during the ...
Self-Generated Hypoxia Leads to Oxidative Stress and Massive Death in Ustilago maydis Populations under Extreme Starvation and Oxygen-Limited Conditions
(MDPI, Basel, 2021)
Ustilago maydis and Saccharomyces cerevisiae differ considerably in their response to water-transfer treatments. When stationary phase cells were transferred to pure water and incubated under limited supply of oxygen, the ...
Bacterial Nanocellulose as a Scaffold for In Vitro Cell Migration Assay
(MDPI, Basel, 2021)
Bacterial nanocellulose (BNC) stands out among polymers as a promising biomaterial due to its mechanical strength, hydrophilicity, biocompatibility, biodegradability, low toxicity and renewability. The use of scaffolds ...
Different Functions of Recombinantly Expressed Domains of Tenascin-C in Glial Scar Formation (vol 11, 3944, 2021)
(Frontiers Media Sa, Lausanne, 2021)
Phenomapping for classification of doxorubicin-induced cardiomyopathy in rats
(Academic Press Inc Elsevier Science, San Diego, 2021)
Cardiomyopathy resistant to treatment is the most serious adverse effect of doxorubicin (dox). The mechanisms of dox-induced cardiomyopathy (DCM) have been extensively studied in dilated forms of DCM. However, efficient ...
Interplay of SOX transcription factors and microRNAs in the brain under physiological and pathological conditions
(Wolters Kluwer Medknow Publications, Mumbai, 2022)
Precise tuning of gene expression, accomplished by regulatory networks of transcription factors, epigenetic modifiers, and microRNAs, is crucial for the proper neural development and function of the brain cells. The SOX ...