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From protein-protein to isoform-isoform interactions: the toolkit to map alternative splicing to interactome
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
Alternative splicing (AS) can impact protein structure and lead to protein-protein
interaction (PPI) rewiring. Available PPI networks neglect alternative splicing isoforms: as
interactions might happen only between a ...
Privacy-preserving Systems Medicine
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
Artificial intelligence (AI) offers game-changing opportunities to healthcare. However, it
also harbors risks to patient privacy in particular when dealing with sensitive clinical data
stored in critical healthcare IT ...
Bioinformatics pipeline for genotyping and genotype - phenotype association study in maize (Zea mays L.)
(Novi Sad : Faculty of Sciences, Department of Biology and Ecology, 2021)
Multidisciplinary research is today commonly used in plant breeding for improving important agronomic
traits. High throughput genotyping technologies and genotype – phenotype association studies as widely
used for improving ...
Combined experimental and theoretical study of Type-II toxin-antitoxin system response to antibiotics
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
Bacterial Type-II toxin-antitoxin (TA) systems, including kacAT in Klebsiella pneumoniae,
respond to antibiotics. We investigated kacAT’s regulation relevant to antibiotic
persistence, which refers to the survival of ...
The use of Active Machine Learning for Protospacer-Adjacent Motif recovery in Class 2 CRISPR-Cas systems
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
The recognition of target DNA sequences during the interference phase of prokaryotic
CRISPR-Cas immunity relies on Protospacer-Adjacent Motif (PAM) sequences, specific
for each Cas effector. PAM identification is a ...
Bioinformatics education course on gene networks reconstruction using online tools
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
Bioinformatics education requires the use of online computer tools for modeling protein-protein
interactions, visual presentation of the networks, access to open databases. The usage of online
bioinformatics tools makes ...
Personalizovana medicina i COVID-19: značaj genomskog profilisanja pacijenata i bioinformatike / Personalized medicine and COVID-19: the importance of genomic host profiling and bioinformatics
(Beograd : Institut za molekularnu genetiku i genetičko inženjerstvo, 2021)
Novi koronavirus SARS-CoV-2, uzročnik upale pluća, sposoban je da zarazi ljude i izazove novu bolest COVID- 19 koja je preopteretila zdravstvene sisteme širom planete i izazvala globalnu ekonomsku krizu. Klinička slika i ...
Precision medicine and COVID-19: importance of host genome profiling and bioinformatics
(Novi Sad : Faculty of Sciences, Department of Biology and Ecology, 2021)
Clinical picture and course of the disease in patients with COVID-19 vary from asymptomatic to lethal.
Precision medicine could discover the cause of this phenomenon by analyzing the individual genomic
profiles of the ...
Translating Bioinformatics Back To Healthcare: Facilitating the use of Artificial Intelligence at UW Medicine
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
It is an opportune time to be engaged in the research and application of informatics
in biomedicine. The increased use of electronic and personal health records and
personal mobile devices is creating many opportunities ...
Computational bioengineering for heart disease
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
In silico clinical trials are a new paradigm for development of a new drug and medical device.
SILICOFCM project is multiscale modeling of familial cardiomyopathy which considers
a comprehensive list of patient specific ...