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An agnostic analysis of the human AlphaFold2 proteome using local protein conformations
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
For more than 30 years, different computational approaches have been implemented to
propose 3D structural models of proteins from their amino acid sequence. Using deep
Learning, AlphaFold 2 obtained particularly remarkable ...
Different approaches in microRNA analysis
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
MicroRNA might serve as a predictive biomarker for treatment response in stem cell
treatment in knee osteoarthritis. Different sample types are going to be collected to
enlighten the true biological role. MicroRNA analysis ...
Integrated relational database of human protein-protein interactions
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
Protein-protein interactions’ data are stored in various publicly available databases of
different types and formats. In this work, a new database for protein-protein interactions
is created by integrating data from ...
Privacy-preserving Systems Medicine
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
Artificial intelligence (AI) offers game-changing opportunities to healthcare. However, it
also harbors risks to patient privacy in particular when dealing with sensitive clinical data
stored in critical healthcare IT ...
Bioinformatics pipeline for genotyping and genotype - phenotype association study in maize (Zea mays L.)
(Novi Sad : Faculty of Sciences, Department of Biology and Ecology, 2021)
Multidisciplinary research is today commonly used in plant breeding for improving important agronomic
traits. High throughput genotyping technologies and genotype – phenotype association studies as widely
used for improving ...
STRENGTHENING THE NEXT-GENERATION SEQUENCING AND BIOINFORMATICS CAPACITIES IN THE REPUBLIC OF SERBIA
(Macedonian Academy of Sciences and Arts, 2023)
Bioinformatics was established at the IMGGE
in collaboration with the Beijing Genomics Institute
(BGI) and with the support of the Government of
the Republic of Serbia. The Center was founded
with the aim of accelerating ...
The use of Active Machine Learning for Protospacer-Adjacent Motif recovery in Class 2 CRISPR-Cas systems
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
The recognition of target DNA sequences during the interference phase of prokaryotic
CRISPR-Cas immunity relies on Protospacer-Adjacent Motif (PAM) sequences, specific
for each Cas effector. PAM identification is a ...
From protein-protein to isoform-isoform interactions: the toolkit to map alternative splicing to interactome
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
Alternative splicing (AS) can impact protein structure and lead to protein-protein
interaction (PPI) rewiring. Available PPI networks neglect alternative splicing isoforms: as
interactions might happen only between a ...
Bioinformatics analysis of eukaryotic positively oriented single stranded RNA viruses
(Novi Sad : Faculty of Sciences, Department of Biology and Ecology, 2021)
Positively oriented single stranded RNA viruses [ssRNA(+)] persistently affect health and well-being of all
eukaryotes, including plants, animals and humans (i.e. SARS-CoV-2, yellow fever, hepatitis C, zika, West Nile,
pepper ...
Combined experimental and theoretical study of Type-II toxin-antitoxin system response to antibiotics
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
Bacterial Type-II toxin-antitoxin (TA) systems, including kacAT in Klebsiella pneumoniae,
respond to antibiotics. We investigated kacAT’s regulation relevant to antibiotic
persistence, which refers to the survival of ...