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Opposing Roles of Calcium and Intracellular ATP on Gating of the Purinergic P2X2 Receptor Channel
(MDPI, Basel, 2018)
P2X2 receptors (P2X2R) exhibit a slow desensitization during the initial ATP application and a progressive, calcium-dependent increase in rates of desensitization during repetitive stimulation. This pattern is observed in ...
Ugt1a1 (ta)(n) promoter genotype: diagnostic and population pharmacogenetic marker in Serbia
(Macedonian Acad Sciences Arts, Skopje, 2018)
The UGT1A1 enzyme is involved in the metabolism of bilirubin and numerous medications. Unconjugated hyper-bilirubinemia, commonly presented as Gilbert syndrome (GS), is a result of decreased activity of the UGT1A1 enzyme, ...
Differences in bioactivity of three endemic Nepeta species arising from main terpenoid and phenolic constituents
(Srpsko biološko društvo, Beograd, i dr., 2018)
Methanol extracts of three endemic Nepeta species were analyzed for their main secondary metabolites, terpenes and phenolics, and further investigated for antioxidant capacity and embryonic toxicity in zebrafish. UHPLC/DAD/(+/-) ...
Physiological and cell ultrastructure disturbances in wheat seedlings generated by Chenopodium murale hairy root exudate
(Springer Wien, Wien, 2018)
Chenopodium murale L. is an invasive weed species significantly interfering with wheat crop. However, the complete nature of its allelopathic influence on crops is not yet fully understood. In the present study, the focus ...
Fingerprinting of the antioxidant status in Alyssum markgrafii shoots during nickel hyperaccumulation in vitro
(Springer Heidelberg, Heidelberg, 2018)
This study investigated the role of antioxidant system of Alyssum markgrafii, during long-term exposure to 0.5 or 1 mM NiCl2 x 6H(2)O in vitro. Applied methodology included sample preparation protocol which reduces oxidation ...
Can untreated PKU patients escape from intellectual disability? A systematic review
(BMC, London, 2018)
Background: Phenylketonuria (PKU) is often considered as the classical example of a genetic disorder in which severe symptoms can nowadays successfully be prevented by early diagnosis and treatment. In contrast, untreated ...
Microbial Production of Violacein and Process Optimization for Dyeing Polyamide Fabrics With Acquired Antimicrobial Properties
(Frontiers Media Sa, Lausanne, 2018)
In the present study, crude bacterial extract containing violacein is investigated for the preparation of antimicrobial polyamide fabrics. The optimal culture conditions of Janthinobacterium lividum (JL) for maximum biomass ...
Chemical composition and antiproliferative potential of dried wild apple and pear tea before and after in vitro simulated digestion
(Srpsko hemijsko društvo, Beograd, 2018)
Decoctions obtained from dried apple and pear fruits were subjected to in vitro digestion in the presence of a food matrix in order to determine changes in the polyphenol content and antiproliferative activity. The total ...
Optimization of ultrasound-assisted extraction of total polyphenolic compounds from Juglans nigra L. leaves
(Srpsko hemijsko društvo, Beograd, 2018)
The ultrasound-assisted extraction of Juglans nigra L. leaves was optimized with respect to total phenolic content (TP) of the extracts by varying the concentration of aqueous ethanol solution (E) and different solvent-to-solid ...
Root malate efflux and expression of TaALMT1 in Serbian winter wheat cultivars differing in Al tolerance
(Sociedad Chilena de la Ciencia del Suelo, 2018)
Aluminium (Al) toxicity in acid soils is a global problem. Here, we investigated Al tolerance in high yielding winter wheat (Triticum aestivum L.) cultivars bred in Serbia. The common relative mot length (RRL) test for Al ...