Pretraživanje
Prikaz rezultata 1-6 od 6
Modulation of SOX2 and SOX3 gene expression during differentiation of human neuronal precursor cell line NTERA2
(Springer, Dordrecht, 2003)
The SOX genes comprise a family of transcriptional regulators implicated in the control of nervous system development. The developing brain is the major site of expression of many Sox genes. Sox2 and Sox3 genes are ...
Analysis of the promoter regions of disease-causing genes in maturity-onset diabetes of the young patients
(Springer, Dordrecht, 2020)
Maturity-onset diabetes of the young (MODY) is a form of monogenic diabetes caused by the variants in MODY-related genes. In addition to coding variants, variants in the promoter region of MODY-related genes can cause the ...
ZBP-89 and Sp3 down-regulate while NF-Y up-regulates SOX18 promoter activity in HeLa cells
(Springer, Dordrecht, 2009)
The aim of this study has been to identify transcription factors involved in transcriptional regulation of the human SOX18 gene expression. Structural analysis revealed that the SOX18 promoter lacks a TATA box, but is ...
Identification and profiling of conserved microRNAs in different developmental stages of crown imperial (Fritillaria imperialis L.) using high-throughput sequencing
(Springer, Dordrecht, 2022)
Background Novel strategies for improvement of ornamental plants and their properties relay on miRNA control of differential plant gene expression modulation. Still, in response to the same abiotic stresses, some conserved ...
Human initiation protein Orc4 prefers triple stranded DNA
(Springer, Dordrecht, 2010)
In higher eukaryotes mechanism of DNA replication origin recognition and binding by origin recognition complex (ORC) is still unknown. Origin transfer studies have shown that origin sites are genetically determined, ...
Functional analysis of novel alpha-1 antitrypsin variants G320R and V321F
(Springer, Dordrecht, 2014)
Alpha-1 antitrypsin (AAT) gene is highly polymorphic, with a large number of rare variants whose phenotypic consequences often remain inconclusive. Studies addressing functional characteristics of AAT variants are of ...