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Identification and validation of differentially expressed transcripts by RNA-sequencing of formalin-fixed, paraffin-embedded (FFPE) lung tissue from patients with Idiopathic Pulmonary Fibrosis
(Biomed Central Ltd, London, 2017)
Background: Idiopathic Pulmonary Fibrosis (IPF) is a lethal lung disease of unknown etiology. A major limitation in transcriptomic profiling of lung tissue in IPF has been a dependence on snap-frozen fresh tissues (FF). ...
Chemical composition and antiproliferative potential of dried wild apple and pear tea before and after in vitro simulated digestion
(Srpsko hemijsko društvo, Beograd, 2018)
Decoctions obtained from dried apple and pear fruits were subjected to in vitro digestion in the presence of a food matrix in order to determine changes in the polyphenol content and antiproliferative activity. The total ...
Optimization of ultrasound-assisted extraction of total polyphenolic compounds from Juglans nigra L. leaves
(Srpsko hemijsko društvo, Beograd, 2018)
The ultrasound-assisted extraction of Juglans nigra L. leaves was optimized with respect to total phenolic content (TP) of the extracts by varying the concentration of aqueous ethanol solution (E) and different solvent-to-solid ...
Root malate efflux and expression of TaALMT1 in Serbian winter wheat cultivars differing in Al tolerance
(Sociedad Chilena de la Ciencia del Suelo, 2018)
Aluminium (Al) toxicity in acid soils is a global problem. Here, we investigated Al tolerance in high yielding winter wheat (Triticum aestivum L.) cultivars bred in Serbia. The common relative mot length (RRL) test for Al ...
The influence of Wilms' tumor 1 gene expression level on prognosis and risk stratification of acute promyelocytic leukemia patients
(Wiley, Hoboken, 2020)
Introduction Patients with acute promyelocytic leukemia (APL) are characterized by the highest expression of Wilms' tumor 1 (WT1) gene compared with other subtypes of acute myeloid leukemia, and yet this molecular marker ...
Identification of Phenolic Compounds from Seed Coats of Differently Colored European Varieties of Pea (Pisum sativum L.) and Characterization of Their Antioxidant and In Vitro Anticancer Activities
(Routledge Journals, Taylor & Francis Ltd, Abingdon, 2016)
To date little has been done on identification of major phenolic compounds responsible for anticancer and antioxidant properties of pea (Pisum sativum L.) seed coat extracts. In the present study, phenolic profile of the ...
Application of Next-Generation Sequencing Technology and Establishment of Biobanks
(Karger, Basel, 2018)
Institute of Molecular Genetics and Genetic Engineering has
become widely recognized as an expert centre for rare diseases
(RD). It is the first institution is Serbia that applied NGS methodology in research and diagnostics ...
Precision medicine and COVID-19: Importance of host genome profiling
(Institute of Molecular Genetics and Genetic Engineering (IMGGE), University of Belgrade, 2023)
Introduction: The clinical picture and the course of the disease in COVID-19 patients, caused by coronavirus SARS-CoV-2, vary from asymptomatic to fatal outcome. As the same agent cause the disease, the
individual genomic ...
Nuclear extract from REL cells contains GATA-1 transcription factor
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 1996)
Preparation of nuclear extracts from different tissues may provide the proteins that regulate gene expression in those tissues. REL (rat erythroleukemia) cells represent a permanent erythroid cell line. They are the most ...
Ascorbate as a key player in plant abiotic stress response and tolerance
(Springer International Publishing, 2018)
During their lifespan, plants are frequently exposed to adverse environmental conditions such as high solar irradiance, drought, heat, chilling, salinity, metal excess, and nutrient deficiency. The effects of these factors ...