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The Role of SOX Transcription Factors in Ageing and Age-Related Diseases
(International Journal of Molecular SciencesInternational Journal of Molecular Sciences, 2023)
The quest for eternal youth and immortality is as old as humankind. Ageing is an inevitable physiological process accompanied by many functional declines that are driving factors for age-related diseases. Stem cell exhaustion ...
Differential Antioxidant Response to Supplemental UV-B Irradiation and Sunlight in Three Basil Varieties
(International Journal of Molecular Sciences, 2023)
Three basil plant varieties (Ocimum basilicum var. Genovese, Ocimum × citriodorum, and Ocimum basilicum var. purpurascens) were grown under moderate light (about 300 µmol photons m−2 s−1) in a glasshouse or growth chamber ...
Red-Light Transmittance Changes in Variegated Pelargonium zonale—Diurnal Variation in Chloroplast Movement and Photosystem II Efficiency
(International Journal of Molecular SciencesInternational Journal of Molecular Sciences, 2023)
Chloroplast movement rapidly ameliorates the effects of suboptimal light intensity by accumulating along the periclinal cell walls, as well as the effects of excess light by shifting to the anticlinal cell walls. These ...
Autologous Platelet and Extracellular Vesicle-Rich Plasma as Therapeutic Fluid: A Review
(MDPI, 2023)
The preparation of autologous platelet and extracellular vesicle-rich plasma (PVRP) has been explored in many medical fields with the aim to benefit from its healing potential. In parallel, efforts are being invested to ...
Sitagliptin Induces Tolerogenic Human Dendritic Cells
(MDPI, 2023)
Sitagliptin, an anti-diabetic drug, is a dipeptidyl peptidase (DPP)-4/CD26 inhibitor with additional anti-inflammatory and immunomodulatory properties. In this study, we investigated for the first time the effect of ...
Can Pharmacogenetic Variants in TPMT, MTHFR and SLCO1B1 Genes Be Used as Potential Markers of Outcome Prediction in Systemic Sclerosis Patients?
(International Journal of Molecular SciencesInternational Journal of Molecular Sciences, 2023)
Systemic sclerosis (SSc) is a rare connective tissue disorder with highest morbidity and mortality among rheumatologic diseases. Disease progression is highly heterogeneous between patients, implying a strong need for ...
Small Cellular Particles from European Spruce Needle Homogenate
(MDPI, 2023)
Small cellular particles (SCPs) are being considered for their role in cell-to-cell communication. We harvested and characterized SCPs from spruce needle homogenate. SCPs were isolated by differential ultracentrifugation. ...
RclS Sensor Kinase Modulates Virulence of Pseudomonas capeferrum
(MDPI, Basel, 2022)
Signal transduction systems are the key players of bacterial adaptation and survival. The orthodox two-component signal transduction systems perceive diverse environmental stimuli and their regulatory response leads to ...
A Machine-Learning-Based Approach to Prediction of Biogeographic Ancestry within Europe
(International Journal of Molecular Sciences, 2023)
Data obtained with the use of massive parallel sequencing (MPS) can be valuable in population genetics studies. In particular, such data harbor the potential for distinguishing samples from different populations, especially ...
Pomegranate Peel Extract Differently Modulates Gene Expression in Gingiva-Derived Mesenchymal Stromal Cells under Physiological and Inflammatory Conditions
(International Journal of Molecular SciencesInternational Journal of Molecular Sciences, 2023)
Pomegranate has shown a favorable effect on gingivitis/periodontitis, but the mechanisms involved are poorly understood. The aim of this study was to test the effect of pomegranate peel extract (PoPEx) on gingiva-derived ...