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Dissolution of copper mineral phases in biological fluids and the controlled release of copper ions from mineralized alginate hydrogels
(IOP Publishing Ltd, Bristol, 2015)
Here we investigate the dissolution behaviour of copper minerals contained within biocompatible alginate hydrogels. Copper has a number of biological effects and has most recently been evaluated as an alternative to expensive ...
Complementary approaches for the evaluation of biocompatibility of Y-90-labeled superparamagnetic citric acid (Fe,Er)(3)O-4 coated nanoparticles
(Elsevier, Amsterdam, 2017)
Magnetic nanoparticles (MNPs) are of immense interest for diagnostic and therapeutic applications in medicine. Design and development of new iron oxide-based MNPs for such applications is of rather limited breadth without ...
The antitumor properties of a nontoxic, nitric oxide-modified version of saquinavir are independent of Akt
(Amer Assoc Cancer Research, Philadelphia, 2009)
Application of the HIV protease inhibitor saquinavir (Saq) to cancer chemotherapy is limited by its numerous side effects. To overcome this toxicity, we modified the original compound by covalently attaching a nitric oxide ...
Effects of Chemotherapy for Metastatic Colorectal Cancer on the TGF-beta Signaling and Related miRNAs hsa-miR-17-5p, hsa-miR-21-5p and hsa-miR-93-5p
(Humana Press Inc, Totowa, 2021)
Metastatic colorectal cancer (mCRC) patients are treated with standard chemotherapeutic drugs in the form of FOLFOX and FOLFIRI regimens. There are no reliable markers that could predict response to chemotherapy for mCRC. ...
Controlled drug release carriers based on PCL/PEO/PCL block copolymers
(Taylor & Francis As, Oslo, 2019)
In order to create a new drug delivery system, the ibuprofen-loaded triblock copolymer PCL/PEO/PCL (PCEC) microspheres with a low PEO content ( lt 2 wt%) were prepared by oil in water (o/w) solvent evaporation technique. ...
Procarboxypeptidase U (TAFI) contributes to the risk of thrombosis in patients with hereditary thrombophilia
(Pergamon-Elsevier Science Ltd, Oxford, 2009)
Introduction: It is considered that high plasma levels of procarboxypeptidase U (proCPU or TAFI) can promote the development of thrombosis, but data comparing proCPU levels in thrombophilia carriers and healthy subjects ...
The characterisation of lactic acid bacteria during the fermentation of an artisan Serbian sausage (Petrovska Klobasa)
(Elsevier Sci Ltd, Oxford, 2011)
Petrovska Klobasa is an artisan Serbian sausage made only from meat and spices without any additives or starter cultures. In order to characterise lactic acid bacteria (LAB) microflora, a total number of 404 LAB strains ...
Factor V Leiden mutation and high FVIII are associated with an increased risk of VTE in women with breast cancer during adjuvant tamoxifen - Results from a prospective, single center, case control study
(Elsevier, Amsterdam, 2015)
Background: Estimates of the risk ratio of tamoxifen-associated venous thromboembolism(VTE) in breast cancer patients range from 2.4 to 7.1. The occurrence of thrombosis in patients with breast cancer complicates the ...
Significance of new prognostic markers in early stage chronic lymphocytic leukemia patients
(Elsevier, Amsterdam, 2011)
Effects of subacute oral warfarin administration on peripheral blood granulocytes in rats
(Pergamon-Elsevier Science Ltd, Oxford, 2012)
Warfarin affects mainly vitamin K dependent (VKD) processes, but the effects on some non-VKD-related activities such as tumor growth inhibition and mononuclear cell-mediated immune reactions were shown as well. In this ...